Tazarotène pour le psoriasis
Zorac
Revu par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSDernière mise à jour 5 Oct 2024
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Note de l'auteur clinique Michael Stewart 06/10/2024: Zorac® gel was discontinued in the UK in 2021. At the time of review there are no skin preparations containing tazarotene available in the UK. Tazarotene skin preparations may still be available in other countries. This medicine leaflet is based on medical information available in the UK at the time of writing and is left here for reference purposes. Please also refer to the manufacturer's information supplied with your medicine.
Apply a thin layer of tazarotene gel each evening before going to bed.
Remember to wash your hands well after using the gel. This will help prevent accidentally getting it on other areas of your skin, which could cause irritation.
En un coup d'œil
Tazarotene is a gel similar to vitamin A, used for small areas of plaque psoriasis.
It works by slowing down the overproduction of skin cells.
Apply a thin layer to affected areas before bed, remembering to wash your hands afterwards.
Do not use on more than 10% of your body, or on your face, scalp, armpits, or behind elbows and knees.
Your skin may become more sensitive to sunlight, so avoid sun exposure.
Common side-effects include skin irritation, itching, or redness.
Tazarotene can harm an unborn baby; discuss contraception with your doctor.
About tazarotene
Type de médicament | A topical retinoid (similar to vitamin A) |
Utilisé pour | Small areas of plaque psoriasis in adults |
Aussi appelé | Zorac® (discontinued) |
Disponible sous forme de | Gel |
Tazarotene is a gel which is applied to the skin to treat plaque psoriasis. Psoriasis is a condition where red scaly patches develop on your skin, called plaques. Some of the most common areas affected are over your elbows and knees and the lower part of your back. The patches may vary in size from time to time and can be itchy. Treatment for psoriasis aims to clear the plaques as much as possible.
Psoriasis is caused by cells in the outer layer of your skin multiplying faster than normal. This causes the older and dead skin cells to build up on the surface of your skin, causing the red scaly patches. Tazarotene works by slowing the overproduction of your skin cells which eases the inflamed, scaly areas.
Before using tazarotene
To make sure this is the right treatment for you, before you start using tazarotene it is important that your doctor knows:
Si vous êtes enceinte, essayez d'avoir un bébé ou allaitez.
Si vous prenez ou utilisez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et complémentaires.
Si vous avez déjà eu une réaction allergique à un médicament.
How to use tazarotene
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about applying tazarotene and will provide you with a full list of the side-effects which you could experience from using it.
Tazarotene gel is available in two strengths. Your doctor will probably prescribe the lower-strength gel for you at first to see how your skin reacts, and then may increase the strength if this is necessary. This allows your doctor to make sure that you have the strength that helps your condition but also reduces the risk of skin irritation.
Apply a thin layer of gel before going to bed each night. Apply it only to the areas of your skin which are affected. Remember to wash your hands straightaway afterwards to make sure you don't get the gel into your eyes or on any healthy areas of your skin by accident.
Do not use the gel on more than 10% of your body area (this is roughly equivalent to the total skin area of one arm). Do not use the gel on your face, scalp, armpits or behind your elbows and knees.
Tirer le meilleur parti de votre traitement
Essayez de respecter vos rendez-vous réguliers avec votre médecin. Cela permet à votre médecin de suivre vos progrès.
If your skin becomes very dry or irritated, it may help to use a moisturiser but do this at least an hour before using tazarotene. It is recommended that you do not use any moisturisers or cosmetics for at least an hour after applying tazarotene gel.
Do not cover any areas of skin that have been treated with tazarotene with a dressing or a bandage.
It is likely that your doctor will suggest a course of treatment of up to three months. You should start to see an improvement in your skin within a week or so, and this improvement will continue for several weeks. You should continue to apply the gel regularly for as long as you have been recommended in order to get the full benefit.
Tazarotene could harm an unborn baby so it is important that you do not become pregnant while you are using the gel. Please make sure you have discussed with your doctor which types of contraception are recommended for you, as some hormonal contraceptives (such as the 'mini pill') are not suitable.
Your skin may become more sensitive to sunlight than normal while you are using tazarotene. Try to avoid sitting out in the sun and do not use sunbeds.
Can tazarotene cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with tazarotene. You will find a full list in the manufacturer's information leaflet supplied with the medicine. The unwanted effects often improve as your body adjusts to the new medicine but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Very common tazarotene side-effects (these affect more than 1 in 10 people) | Que puis-je faire si je ressens cela ? |
Skin itching, irritation, redness, a burning sensation, | Try applying a thinner layer of gel and make sure you avoid getting the gel on any healthy areas of your skin. If this continues, speak with your doctor |
Common tazarotene side-effects (these affect fewer than 1 in 10 people) | Que puis-je faire si je ressens cela ? |
Peeling, rash or worsening of your condition | Try applying a thinner layer of gel and make sure you avoid getting the gel on any healthy areas of your skin. If this continues, speak with your doctor |
If you experience any other symptoms which you think may be due to the preparation, please speak with your doctor or pharmacist for further advice.
How to store tazarotene
Gardez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.
Informations importantes sur tous les médicaments
Informations importantes sur tous les médicaments
Si vous achetez des médicaments, vérifiez avec un pharmacien qu'ils sont sûrs à prendre avec vos autres médicaments.
If you are having an operation or dental treatment, please tell the person carrying out the treatment which medicines you are taking or using.
Cette préparation est à utiliser uniquement sur la peau. Si quelqu'un en avale accidentellement, rendez-vous au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.
Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Site web de Yellow Card.

Vous n'êtes pas sûr de mélanger des médicaments ?
Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.
Questions fréquemment posées
Can tazarotene cure my plaque psoriasis permanently?
Tazarotene aims to clear the plaques as much as possible by slowing the overproduction of skin cells. While it helps to improve your skin, the article does not state that it offers a permanent cure for psoriasis. You should continue to apply the gel regularly for as long as your doctor recommends to get the full benefit.
Are there any specific types of contraception I should avoid while using tazarotene?
Yes, it is important that you do not become pregnant while using tazarotene as it could harm an unborn baby. Some hormonal contraceptives, such as the 'mini pill', are not suitable. You should discuss with your doctor which types of contraception are recommended for you.
What should I do if my skin becomes very dry or irritated after applying tazarotene?
If your skin becomes very dry or irritated, you can use a moisturiser, but apply it at least an hour before using tazarotene. It's recommended not to use any moisturisers or cosmetics for at least an hour after applying the gel. If irritation or dryness continues, you should speak with your doctor.
How long will I need to use tazarotene gel?
It is likely that your doctor will suggest a course of treatment of up to three months. You should start to see an improvement in your skin within a week or so, and this improvement should continue for several weeks. It's important to continue applying the gel regularly for as long as recommended to get the full benefit.
What should I do if I accidentally get tazarotene gel in my eyes?
The article advises to wash your hands straight away after applying the gel to make sure you don't get it into your eyes by accident. While it doesn't specify what to do if it enters your eyes, general advice for medicated gel is to rinse thoroughly with water, and contact a healthcare professional if irritation persists.
Lectures complémentaires et références
- Manufacturer's PIL, Zorac® gel; Allergan Ltd, The electronic Medicines Compendium. Dated July 2018.
- Médicaments Complets BNF 89e Édition; Association Médicale Britannique et Société Royale Pharmaceutique de Grande-Bretagne, Londres.
À propos de l'auteurVoir la biographie complète

Michael Stewart, MRPharmS
Responsable de l'examen des notices de médicaments – Contractuel, Pharmacien
BPharm (Hons), MRPharmS
Michael est un pharmacien communautaire exerçant dans les Midlands et le South Yorkshire avec plus de 20 ans d'expérience dans le conseil sur les médicaments et les conditions médicales. Il possède une solide expérience en formation dans le domaine de la santé, ayant produit et dispensé des cours de formation pour les équipes de pharmacie et le personnel des établissements de soins résidentiels, y compris les infirmières. Il a également contribué aux comités consultatifs de pharmacie pour la gestion des affections de faible gravité dans la communauté.
À propos du critique

Sid Dajani
Sultan Dajani a obtenu son diplôme à la London School of Pharmacy en 1994 et est devenu le plus jeune membre élu du conseil de la Royal Pharmaceutical Society depuis sa fondation en 1842.
Historique de l'article
Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.
Article également disponible en Anglais, Allemand, Espagnol, Français, Italien, Portugais, Hindi, Hébreu, Arabe, and Suédois.
Prochaine révision prévue : 9 oct. 2027
5 Oct 2024 | Dernière version

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