activin A receptor like type 1
Dernière mise à jour 20 mai 2021
Respecte les directives éditoriales
- TéléchargerTélécharger
- Partager
- Language
- Discussion
- Version audio
- Ajouter aux sources préférées sur Google
La ACVRL1 gene provides instructions for making a protein called activin receptor-like kinase 1. This protein is found on the surface of cells, especially in the lining of developing arteries.
Normal function
La ACVRL1 gene provides instructions for making a protein called activin receptor-like kinase 1. This protein is found on the surface of cells, especially in the lining of developing arteries.
The ACVRL1 protein is a receptor. It acts as a "lock" waiting for a specific protein, called its ligand, to serve as the "key." In the case of the ACVRL1 protein, the ligand is called transforming growth factor beta. The interaction between these proteins plays a role in the development of blood vessels. In particular, this protein interaction is involved in the specialization of new blood vessels into arteries or veins.
Conditions referring to this gene or chromosome
Other names
activin A receptor type II-like 1
activin A receptor type IL
Activin A receptor, type II-like kinase 1
ACVL1_HUMAN
ACVRLK1
ALK-1
ALK1
EC 2.7.1.37
HHT
HHT2
ORW2
Serine/threonine-protein kinase Receptor R3 Precursor
SKR3
TGF-B Superfamily Receptor Type I
Related patient information and medicines
Patient information leaflet
Médicament contre la nausée
Variée medicines are available to treat nausea. Listed below are some of the more commonly prescribed medicines: Cinnarizine , cyclizine , promethazine - these medicines belong to a group of medicines called antihistamines. Th... It is thought that antihistamines block histamine 1 (H1) receptors in the area of the brain which creates nausea in.
Patient information leaflet
Myasthénie grave
Myasthenia gravis (MG) est a condition where muscles become easily tired and weak. It is due to a problem with how... What causes myasthenia gravis. Myasthenia gravis is an autoimmune disease. This means that the immune system (which normally protects the body from infections) mistakenly attacks itself. (Other autoimmune diseases include type 1.
Patient information leaflet
Puis-je prendre Alogliptin et Rybelsus ensemble ?
Prendre alogliptin and Rybelsus (semaglutide) together can significantly increase the risk of your blood sugar dropping too low (hypoglycaemia). Alogliptin (a DPP-4 inhibitor) prevents the breakdown of natural hormones that lower blood sugar, while Rybelsus (a GLP-1 receptor agonist) mimics those same hormones. Using both is like 'doubling up' on.
Patient information leaflet
Diabète et maladie
. Sick day diabetes des directives Le suivant directives is provided by Diabetes UK: Contact your general practice or diabetes team who will help you if you have any queries or if you are unsure about what to do. There is also further information in the following sections on Diabète de type 1 et Type 2 diabetes. On GLP-1 receptor agonists (.
Patient information leaflet
Insuline
Insuline is a hormone made naturally in the body by the pancreas. This hormone controls the level of sugar (glucose) in the blood. People with diabetes need treatment to control the level of sugar (glucose) in their blood. There are two different types of diabetes: Type 1 diabetes Type 1 diabetes is the type of diabetes that typically develops in.
Patient information leaflet
Diabète de type 2
Type 2 diabetes can occur at any age, including during childhood, but it occurs mainly in people aged over 40. What is type 2 diabetes. Type 2 diabetes and its symptoms tend to develop gradually (over weeks or months). This is because in type 2 diabetes you still make insulin (unlike in type 1 diabetes ). However, you develop type 2 diabetes.
Lectures complémentaires et références
- activin A receptor like type 1; MedlinePlus, National Library of Medicine.
- Azuma H. Genetic and molecular pathogenesis of hereditary hemorrhagic telangiectasia. J Med Invest. 2000 Aug;47(3-4):81-90.
- Lebrin F, Deckers M, Bertolino P, Ten Dijke P. TGF-beta receptor function in the endothelium. Cardiovasc Res. 2005 Feb 15;65(3):599-608. doi: 10.1016/j.cardiores.2004.10.036.
- Lesca G, Plauchu H, Coulet F, Lefebvre S, Plessis G, Odent S, Riviere S, Leheup B, Goizet C, Carette MF, Cordier JF, Pinson S, Soubrier F, Calender A, Giraud S; French Rendu-Osler Network. Molecular screening of ALK1/ACVRL1 and ENG genes in hereditary hemorrhagic telangiectasia in France. Hum Mutat. 2004 Apr;23(4):289-99. doi: 10.1002/humu.20017.
- Letteboer TG, Zewald RA, Kamping EJ, de Haas G, Mager JJ, Snijder RJ, Lindhout D, Hennekam FA, Westermann CJ, Ploos van Amstel JK. Hereditary hemorrhagic telangiectasia: ENG and ALK-1 mutations in Dutch patients. Hum Genet. 2005 Jan;116(1-2):8-16. doi: 10.1007/s00439-004-1196-5. Epub 2004 Oct 23.
- Pawlikowska L, Tran MN, Achrol AS, Ha C, Burchard E, Choudhry S, Zaroff J, Lawton MT, Castro R, McCulloch CE, Marchuk D, Kwok PY, Young WL; UCSF BAVM Study Project. Polymorphisms in transforming growth factor-beta-related genes ALK1 and ENG are associated with sporadic brain arteriovenous malformations. Stroke. 2005 Oct;36(10):2278-80. doi: 10.1161/01.STR.0000182253.91167.fa. Epub 2005 Sep 22.
- van den Driesche S, Mummery CL, Westermann CJ. Hereditary hemorrhagic telangiectasia: an update on transforming growth factor beta signaling in vasculogenesis and angiogenesis. Cardiovasc Res. 2003 Apr 1;58(1):20-31. doi: 10.1016/s0008-6363(02)00852-0.
Participez à la conversation
Partagez vos pensées ou expériences avec les autres dans notre communautés de patients.
Demandez, partagez, connectez-vous.
Parcourez les discussions, posez des questions et partagez vos expériences sur des centaines de sujets de santé.
Inscrivez-vous à la newsletter Patient
Votre dose hebdomadaire de conseils de santé clairs et fiables - rédigés pour vous aider à vous sentir informé, confiant et maître de la situation.
En vous abonnant, vous acceptez notre Politique de confidentialité. Vous pouvez vous désabonner à tout moment. Nous ne vendons jamais vos données.