Can I take Iron supplements and Wellbutrin together?
Drug interaction guide
Originally published 25 Jan 2026
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There is no known direct interaction between iron supplements and Wellbutrin (bupropion). However, both substances can occasionally cause stomach-related side effects like nausea or constipation, which might be more noticeable if taken together.
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Why this happens
Iron supplements and bupropion are processed by the body through different pathways. Iron is absorbed in the digestive tract and does not interfere with the liver enzymes that break down bupropion. Furthermore, they do not compete for the same receptors in the brain or body.
What you should do
You can safely take these together. To reduce the risk of an upset stomach, you may wish to take your iron supplement with food (unless your doctor has told you otherwise) and take your Wellbutrin at its usual scheduled time. If you experience significant constipation, ensure you drink plenty of water and speak to a pharmacist.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Clause de non-responsabilité
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historique de l'article
Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.
25 janvier 2026 | Publié à l'origine
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