Can I take Metformin and Clopidogrel together?

Pourquoi cela se produit

Clopidogrel and metformin are processed by different pathways in the body. Clopidogrel is an antiplatelet medicine that works on blood cells to prevent clots, while metformin works on the liver and muscles to improve insulin sensitivity. They do not interfere with each other's absorption, metabolism, or effectiveness.

You can safely take these two medicines together as prescribed by your doctor. However, always monitor your blood sugar levels regularly and watch for any unusual bruising or bleeding, which are side effects of clopidogrel. If you are scheduled for surgery, ensure your doctor knows you are taking clopidogrel, as it may need to be paused.

Risque de saignement

Clopidogrel thins your blood. You are at a higher risk of serious bleeding. Seek urgent medical help if you have a fall or head injury, or if you notice signs of internal bleeding such as black, tarry stools or vomiting blood. You must tell your surgeon or dentist that you are taking clopidogrel before any procedure, as you may need to stop taking it temporarily to prevent excessive bleeding.

Acidose lactique

In rare cases, metformin can cause a serious build-up of acid in the blood. Seek immediate medical attention if you experience severe vomiting, stomach ache, muscle cramps, or a general feeling of being very unwell with extreme tiredness.

Severe kidney problems

You must not take metformin if you have severe kidney failure. Your doctor should check your kidney function before you start and at least once a year while taking it.

Déshydratation sévère ou infection

Si vous développez des vomissements sévères, de la diarrhée ou une forte fièvre, vous devez arrêter temporairement la prise de la metformine et contacter votre médecin pour éviter une surcharge rénale.

Alcool

It is best to avoid or strictly limit alcohol while taking metformin. Drinking alcohol can increase the risk of a rare but serious condition called lactic acidosis (a build-up of lactic acid in the blood) and can also increase the risk of low blood sugar (hypoglycaemia).

It is best to avoid or strictly limit alcohol while taking clopidogrel. Both alcohol and clopidogrel can irritate the stomach lining and increase the risk of internal bleeding, particularly in the stomach and intestines.

Absorption de la vitamine B12

L'utilisation à long terme de la metformine peut empêcher votre corps d'absorber suffisamment de vitamine B12 provenant de votre alimentation. Vous devrez peut-être faire vérifier votre taux de B12 par votre médecin ou prendre un supplément si vous développez des symptômes tels qu'une fatigue extrême ou une langue douloureuse.

Taking multiple medicines? Our Vérificateur d'Interactions Médicamenteuses helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Avertissement

Ces informations sont fournies à des fins éducatives générales uniquement et ne doivent pas être considérées comme un substitut aux conseils médicaux professionnels. Consultez toujours votre médecin généraliste, votre pharmacien ou un autre professionnel de santé qualifié avant de prendre des décisions concernant vos médicaments. Les circonstances individuelles peuvent varier, et seul un professionnel de santé connaissant votre historique médical peut fournir des conseils personnalisés.