Puis-je prendre de la morphine et du paracétamol ensemble ?

It is generally considered safe to take morphine et paracétamol together.

Paracetamol and morphine have different 'mechanisms of action' (the way they work in the body). Paracetamol works mainly in the central nervous system to reduce pain signals, while morphine attaches to specific 'opioid receptors' to block pain.

Because they don't interfere with each other's absorption or breakdown in the liver, they can be used safely at the same time.

How to take morphine and paracetamol safely

• Always ensure you do not exceed the maximum dose of paracetamol (usually 4000mg or 8x500mg tablets in 24 hours).

• Always follow the specific instructions for your morphine dosage.

• If you are taking a 'co-compound' medicine (such as Co-codamol), check if it already contains paracetamol before taking extra.

Asthme ou problèmes respiratoires

Morphine can cause life-threatening breathing difficulties; do not take it if you have severe asthma or chronic obstructive pulmonary disease (COPD).

Maladie du foie ou consommation élevée d'alcool

Taking more than the recommended dose of paracetamol, or taking it while drinking heavily, can cause fatal liver failure. Never take more than one product containing paracetamol at a time.

Opioid dependence and withdrawal

Morphine carries a high risk of addiction and dependence. Long-term use can lead to withdrawal symptoms if stopped suddenly; always follow a tapering schedule.

Opioid use with alcohol or sedatives

Mixing morphine with alcohol or benzodiazepines (sleeping pills) is extremely dangerous and can lead to fatal respiratory arrest or coma.

Alcool

You must not drink alcohol while taking morphine. Alcohol can dangerously increase the sedative effects of morphine, leading to extreme sleepiness, breathing difficulties, and a potentially fatal overdose.

Some long-acting morphine capsules can also release the entire dose at once into your system if taken with alcohol (known as 'dose dumping').

It is best to avoid or strictly limit alcohol when taking paracetamol. Combining alcohol and paracetamol increases the risk of serious liver damage.

Taking multiple medicines? Our Vérificateur d'Interactions Médicamenteuses helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Avertissement

Ces informations sont fournies à des fins éducatives générales uniquement et ne doivent pas être considérées comme un substitut aux conseils médicaux professionnels. Consultez toujours votre médecin généraliste, votre pharmacien ou un autre professionnel de santé qualifié avant de prendre des décisions concernant vos médicaments. Les circonstances individuelles peuvent varier, et seul un professionnel de santé connaissant votre historique médical peut fournir des conseils personnalisés.