Comprimés de co-cyprindiol
Clairette, Dianette
Revu par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSLast updated 4 déc. 2024
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Co-cyprindiol tablets are prescribed for women with certain skin conditions when contraception is also required.
Carefully read and follow the printed information leaflet from inside the pack.
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About co-cyprindiol
Type de médicament | A hormone treatment |
Utilisé pour | Severe acne or hirsutism in women |
Aussi appelé | Clairette®; Dianette® |
Disponible sous forme de | Comprimés |
Co-cyprindiol is prescribed for two different skin conditions in women - l'acné et l'hirsutisme.
Acne is a common skin condition which is often treated by skin creams or antibiotic tablets. You will have been prescribed co-cyprindiol for acne if other treatments have not been sufficiently effective for you.
Hirsutism is a condition where dark, thick hair grows in places where it doesn't usually grow in women, such as on the face or chest.
Co-cyprindiol contains two ingredients, ethinylestradiol and cyproterone. Ethinylestradiol is an oestrogen, which is a female sex hormone. Cyproterone is an anti-androgen. Androgens are responsible for stimulating the glands on your skin which produce an oil (sebum) and they also encourage hair growth. Co-cyprindiol works by reducing the amount of androgen you produce, which helps to clear acne and reduces excess hair growth.
Co-cyprindiol is also an oral contraceptive pill. Although it is not prescribed solely for this purpose, it can be helpful if you have one of the skin conditions mentioned above and also wish to take oral contraception.
Before taking co-cyprindiol
Retour au sommaireSome medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking co-cyprindiol it is important that your doctor knows:
If you are breastfeeding, or if you think you could be pregnant.
If you have ever had an unwanted blood clot, or blood vessel problems.
If you have a breast lump, or if you have had breast cancer.
If you have any problems with the way your liver works, or if you have gallstones.
Si vous avez des saignements vaginaux autres que votre règle mensuelle habituelle.
If you have high blood levels of fats (lipids), or if you have been told you have high blood levels of prolactin.
If you have any of the following conditions: heart disease, migraine, systemic lupus erythematosus (SLE), porphyria, sickle cell disease, or an inflammatory bowel condition.
If you have ever been diagnosed with depression, or if you have had a transient ischaemic attack (called a 'TIA' or 'mini stroke'), or if you have had haemolytic uraemic syndrome.
If during a pregnancy you have had problems such as severe itching and blistering of your skin, jaundice, or any involuntary jerky movements.
Si vous avez déjà eu une réaction allergique à un médicament.
If you are taking any other medicines, including those available to buy without a prescription and herbal or complementary medicines. This is important because some medicines may stop combined hormonal contraceptives from working properly.
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How to take co-cyprindiol
Retour au sommaireBefore you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about co-cyprindiol, and it will also provide you with a full list of side-effects which you could experience from taking it.
Starting on the first day of your next period, take one tablet daily for 21 days and then have seven days without taking a tablet. Continue to take one tablet daily for 21 days and then have seven pill-free days until your doctor tells you otherwise.
You should take your tablets at the same time of day each day. This is particularly important if you are taking them to prevent pregnancy. If you forget to take a tablet on time, take it as soon as you remember, and then take the next dose at your usual time (even if this means taking two tablets on the same day). If you are more than 12 hours late taking a tablet, your protection against pregnancy could be reduced. In this case, for the following seven days you must either use a barrier method of contraception such as a condom, or avoid sex. If these seven days run beyond the end of your packet of pills, start the next packet straightaway without any tablet-free days. This means you may not have a period until the end of the two packets.
Tirer le meilleur parti de votre traitement
Retour au sommaireTry to keep your regular appointments with your doctor or clinic. This is so your doctor can check on your progress. You will need to have your blood pressure checked from time to time.
If you suspect at any time that you may be pregnant, stop taking co-cyprindiol and see your doctor or pharmacist for a pregnancy test straightaway.
Important: if you have a bout of being sick (vomiting) or diarrhoea, it can reduce the effectiveness of the contraception. If this happens, use a condom if you have sex during the illness and for seven days after you recover. If the illness occurs during the last week of your tablets, miss out the seven pill-free days and start a new pack of tablets straightaway. This means you may not have a period until the end of the two packets.
Please note: co-cyprindiol taken as a contraceptive will not protect you from sexually transmitted infections or HIV infection. If you are concerned about either of these, please ask your pharmacist or doctor for advice on safe sex.
There is a slightly increased risk of a clot in a blood vessel (thromboembolism) with hormonal contraceptives like co-cyprindiol, particularly during the first year of use. Travelling that involves long periods of sitting still (for example, flying for more than three hours) can add to the risk of a blood clot. It's always a good idea to exercise your feet and ankles regularly while travelling, and you may wish to consider wearing flight socks during long flights.
Taking hormonal contraception can increase the risk of some types of cancer. Research suggests a small increased risk of breast and cervical cancer in women taking co-cyprindiol. Your doctor will be able to discuss the risks of this with you.
Treatment with hormones can affect your mood and may impact on your mental health. Speak to your doctor if you are worried about any mood changes after starting treatment with co-cyprindiol.
Before having any kind of surgery, you must tell your doctor or surgeon that you are taking these tablets. This is because your doctor may decide that you need to stop the treatment for a period of time to reduce your risk of unwanted blood clots.
It is likely to take at least 3-4 months for your skin condition to clear up. Your doctor will regularly review your progress during this time. If you still need contraception once the course of treatment with co-cyprindiol has stopped, an alternative contraceptive pill will be prescribed for you.
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Can co-cyprindiol cause problems?
Retour au sommaireAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the common ones associated with co-cyprindiol. You will find a full list in the manufacturer's information leaflet supplied with the tablets. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common co-cyprindiol side-effects (these affect fewer than 1 in 10 women) | Que puis-je faire si je ressens cela ? |
Sensation de malaise (nausée), douleur au ventre (abdominale) | Eat simple meals - avoid rich and spicy food (see also the information above on bouts of sickness) |
Maux de tête | Ask your pharmacist to recommend a suitable painkiller. If the headache continues or is sudden and severe, contact your doctor for advice |
Breast tenderness, increased weight, mood changes | Si cela pose problème, parlez-en à votre médecin |
Important: co-cyprindiol can have some serious side-effects, but these are very uncommon. If you experience any of the following symptoms, stop taking the tablets and contact your doctor for advice straightaway:
Any sudden or severe chest pain.
Any sudden breathlessness or if you cough up any blood.
Any swelling or pain in a leg.
Une douleur abdominale intense.
An unusually painful or severe headache, or any loss of your sight or hearing, or any difficulty swallowing.
A bad fainting attack, a fit, or any numbness on one side of your body,
Tout jaunissement de votre peau ou du blanc de vos yeux (jaunisse).
Si vous ressentez d'autres symptômes que vous pensez être dus aux comprimés, veuillez consulter votre médecin ou votre pharmacien pour obtenir des conseils supplémentaires.
How to store co-cyprindiol
Retour au sommaireGardez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.
Informations importantes sur tous les médicaments
Retour au sommaireInformations importantes sur tous les médicaments
Never take more than the prescribed dose. If you suspect that you or someone else might have an overdose of this medicine, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Si vous achetez des médicaments, vérifiez toujours avec un pharmacien qu'ils sont sûrs à prendre avec vos autres médicaments.
Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.
If you have any questions about this medicine, please ask your pharmacist for advice.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Yellow Card website.

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Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.
Lectures complémentaires et références
- Manufacturer's PIL, Dianette®; Bayer plc, The electronic Medicines Compendium. Dated February 2023.
- Médicaments Complets BNF 89e Édition; Association Médicale Britannique et Société Royale Pharmaceutique de Grande-Bretagne, Londres.
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Historique de l'article
Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.
Prochaine révision prévue : 4 décembre 2027
4 déc. 2024 | Dernière version

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