Diazoxide
Eudemine
Revu par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSLast updated 19 déc. 2022
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Diazoxide is for the treatment of long-term low blood sugar levels caused by your pancreas producing too much insulin.
The tablets are usually taken two or three times a day.
Remember to keep your regular doctor's appointments so that your progress can be monitored.
At a glance
Diazoxide (Eudemine®) is a medicine for chronic hypoglycaemia, a condition with low blood sugar.
It works by increasing blood sugar levels, especially when low levels are caused by too much insulin.
Take tablets exactly as prescribed by your doctor, usually two or three times a day.
You will need regular blood tests and blood pressure checks to monitor your progress.
Common side-effects include feeling sick, dizzy, or having swollen feet and ankles.
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About diazoxide
Type de médicament | Thiazide |
Utilisé pour | Chronic hypoglycaemia |
Aussi appelé | Eudemine® |
Disponible sous forme de | Comprimés |
Diazoxide is used to treat a long-term condition called chronic hypoglycaemia. People with this condition have low amounts of sugar in their blood. You will have been prescribed diazoxide if the low levels of sugar in your blood are caused by your pancreas producing too much insulin. Insulin is the hormone that controls the levels of sugar in your blood. Your pancreas can produce too much insulin if you have a growth in your pancreas, or if you have a higher number of insulin-producing cells (called islet cells) than normal. Diazoxide works by increasing blood sugar levels.
Alongside diazoxide, you may also be prescribed a 'water' tablet (a diuretic). This is because diazoxide can cause fluid retention, and taking a diuretic will help prevent this.
Before taking diazoxide
Retour au sommaireSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking diazoxide it is important that your doctor knows:
Si vous êtes enceinte, essayez d'avoir un bébé ou allaitez.
If you have heart disease or blood pressure problems.
Si vous avez des problèmes avec le fonctionnement de vos reins.
If you have ever had gout, a condition which causes pain and swelling in the toe joints.
Si vous prenez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et les médecines complémentaires.
Si vous avez déjà eu une réaction allergique à un médicament.
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How to take diazoxide tablets
Retour au sommaireBefore you start this treatment, read the manufacturer's printed information leaflet from inside your pack. The leaflet will give you more information about diazoxide and a full list of side-effects which you may experience from taking it.
Your dose will be adjusted to suit your condition, so take the tablets exactly as your doctor tells you to. Your dose will be printed on the label of the pack to remind you. You will probably need to take the tablets two or three times a day. Try to take your doses at the same times each day, as this will help you to remember to take them.
It may help to swallow the tablets with a drink of water. You can take them before or after meals.
If you do forget to take a dose, take it as soon as you remember. However, if when you remember, it is nearly time for your next dose, then leave out the forgotten dose. Do not take two doses together to make up for a missed dose.
Tirer le meilleur parti de votre traitement
Retour au sommaireTry to keep your regular appointments with your doctor. This is so your doctor can check on your progress. You will need to have blood tests and your doctor will want to monitor your blood pressure regularly. Children taking diazoxide will need their growth and development checked.
Keep taking these tablets until your doctor tells you otherwise. Treatment with diazoxide is usually long-term.
If you are having an operation or medical treatment, tell the person carrying out the treatment that you are taking diazoxide. This is because it can interfere with the way some anaesthetics work.
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Can diazoxide cause problems?
Retour au sommaireAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with diazoxide. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Possible diazoxide side-effects | Que puis-je faire si je ressens cela ? |
Feeling sick (nausea) or being sick (vomiting), lack of appetite | Nausea usually only lasts for the first couple of weeks of treatment. Stick to a simple, well-balanced diet of non-spicy foods |
Feeling faint or dizzy, especially when you stand up | Getting up slowly may help. If you feel dizzy, sit down for a few moments until the feeling passes. Do not drive and do not use tools or machines while you feel dizzy |
Feeling shaky, stiff awkward movements, or unusual eye movements | Let your doctor know as soon as possible |
Swollen feet and ankles, a fast heartbeat, changes in body hair | Si l'un de ces éléments devient problématique, parlez-en à votre médecin |
Si vous ressentez d'autres symptômes que vous pensez être dus à ce médicament, parlez-en à votre médecin ou à votre pharmacien.
How to store diazoxide
Retour au sommaireGardez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.
Informations importantes sur tous les médicaments
Retour au sommaireInformations importantes sur tous les médicaments
Ne prenez jamais plus que la dose prescrite. Si vous soupçonnez que vous ou quelqu'un d'autre avez pris une surdose de ce médicament, rendez-vous au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.
Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Yellow Card website.

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Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.
Questions fréquemment posées
What is chronic hypoglycaemia, and how does diazoxide help with it?
Chronic hypoglycaemia is a long-term condition where there are persistently low levels of sugar in your blood. Diazoxide is prescribed when these low blood sugar levels are due to your pancreas producing too much insulin. Insulin is the hormone that regulates blood sugar, and conditions like a growth in the pancreas or an increased number of insulin-producing cells can lead to excessive insulin production. Diazoxide works by increasing your blood sugar levels to counteract this.
Why might I need to take a 'water' tablet along with diazoxide?
You might be prescribed a 'water' tablet, also known as a diuretic, alongside diazoxide because diazoxide can cause your body to retain fluid. Taking a diuretic helps to prevent this fluid retention from becoming an issue.
What should I do if I forget to take a dose of diazoxide?
If you forget to take a dose, take it as soon as you remember. However, if it's almost time for your next scheduled dose, then you should skip the missed dose entirely. Do not take two doses at once to compensate for the forgotten dose.
How long will I need to take diazoxide?
Treatment with diazoxide is typically long-term. You should keep taking these tablets until your doctor specifically tells you to stop. They will monitor your progress through regular appointments and blood tests.
Can diazoxide affect other medical treatments I might have?
Yes, diazoxide can interfere with the way some anaesthetics work. If you are scheduled for any operation or medical treatment, it's important to inform the healthcare professional carrying out the treatment that you are taking diazoxide.
What kind of monitoring will my doctor do while I'm on diazoxide?
Your doctor will want to monitor your progress through regular appointments. This will include having blood tests and regularly checking your blood pressure. If a child is taking diazoxide, their growth and development will also need to be checked.
Lectures complémentaires et références
- Manufacturer's PIL, Eudemine® 50 mg Tablets; RPH Pharmaceuticals AB, The electronic Medicines Compendium Dated April 2021.
- Médicaments Complets BNF 89e Édition; Association Médicale Britannique et Société Royale Pharmaceutique de Grande-Bretagne, Londres.
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About the authorView full bio

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Historique de l'article
Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.
Prochaine révision prévue : 18 juin 2027
19 déc. 2022 | Dernière version

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