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Cyprotérone - un anti-androgène pour les hommes

Cyprostat, Androcur

Take cyproterone tablets with a drink of water and something to eat.

Cyproterone may make you feel tired or weak. If this happens, do not drive and do not use tools or machines.

Cyproterone can affect the way your liver works and the way your adrenal glands work. Your doctor will discuss the risk of these with you before you start the treatment.

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About cyproterone

Type de médicament

Anti-androgen

Utilisé pour

To treat prostate cancer in men; to control hypersexuality in men

Également appelé

Cyprostat® (used for prostate cancer); Androcur® (used for hypersexuality)

Disponible en

Tablettes

Cyproterone belongs to a group of medicines known as anti-androgens. This means that it blocks the actions of male sex hormones called androgens, and it also reduces the amount of male hormones your body produces. This anti-androgen action can be helpful in the treatment of two different conditions - in the treatment of prostate cancer, and to control the sex drive in men with hypersexuality.

In prostate cancer, the cancer cells need the male hormone testosterone to grow and multiply well. Hormone treatments like cyproterone block the effect of testosterone on prostate cancer cells. This slows down the growth of the cancer. Cyproterone also helps to reduce symptom 'flares' and side-effects from other treatments which may be used for the cancer, or following surgery.

In men who have hypersexuality, cyproterone is used to control sexual desire or deviation. If you are prescribed cyproterone for this reason, your doctor will ask you to sign an agreement before you start the treatment.

Cyproterone is also found in very low doses in a contraceptive tablet called co-cyprindiol. It is useful for managing acne or excess hair growth (hirsutism) whilst also providing contraception.

Before taking cyproterone

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking cyproterone it is important that your doctor knows:

  • If you are under 18 years old. Cyproterone is not recommended for this age group.

  • If you are depressed.

  • If you have any problems with the way your liver works, or if you drink a lot of alcohol.

  • Si vous êtes diabétique.

  • If you have blood vessel problems, such as if you have ever had a blood clot in a leg or lung.

  • If you have a type of anaemia known as sickle cell anaemia.

  • If you have ever had a type of brain tumour called meningioma, or if you have been diagnosed with another type of cancer (other than prostate cancer if that is what you are being treated for).

  • Si vous prenez ou utilisez d'autres médicaments. Cela comprend tous les médicaments que vous prenez et qui sont disponibles sans ordonnance, ainsi que les médicaments à base de plantes et les médicaments complémentaires.

  • Si vous avez déjà eu une réaction allergique à un médicament.

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How to take cyproterone

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about cyproterone and will provide you with a full list of the side-effects which you may experience from taking it.

  • Take cyproterone exactly as your doctor tells you to. How you should take the tablets will depend on what condition you are being treated for, so your doctor will give you full directions. Your dose will also be printed on the label of the pack to remind you about what the doctor said to you.

  • Take your doses with a snack, or just after eating a meal. Swallow the tablets with a drink of water.

  • Try to take cyproterone at the same times of day each day. This will help you to remember to take your doses regularly.

  • If you forget to take a dose, take it as soon as you remember unless your next dose is due. If it is nearly time for your next dose then take the next dose when it is due but leave out the forgotten dose. Do not take two doses together to make up for a missed dose.

Tirer le meilleur parti de votre traitement

  • Please keep your regular appointments with your doctor. Your doctor will want you to have some blood tests both before and during your treatment. The tests will check the levels of your blood cells, and that your liver stays healthy. Your doctor will also want to check that your adrenal glands are not being affected by the treatment.

  • Cyproterone can make you feel tired or weak. If this happens to you, do not drive and do not use tools or machines, as these symptoms may put others as well as yourself at risk.

  • Your doctor may recommend you do not drink alcohol while you are on cyproterone. This is because regularly drinking alcohol can stop cyproterone from working as well as it should.

  • When you have been taking cyproterone for some weeks, your sperm count will reduce and you are likely to become unable to father a child. You must not, however, rely on cyproterone as a contraceptive. Although this infertility is likely to reverse when you stop taking cyproterone, you should speak with your doctor if you are thinking of having children in the future.

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Can cyproterone cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with cyproterone. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common cyproterone side-effects


Que puis-je faire si je suis confronté à cette situation ?

Reduced sperm count

Your doctor will discuss this with you before your treatment starts

Feeling tired or weary

Dans ce cas, ne conduisez pas et n'utilisez pas d'outils ou de machines.

Hot flushes and sweating

Try to keep yourself cool by wearing light and airy clothes

Changes in your weight, feeling depressed or restless, breast tenderness, feeling short of breath

Si l'un d'entre eux devient gênant, parlez-en à votre médecin.

Important: cyproterone can affect the way your liver works and the way your adrenal glands work. Your doctor will discuss this with your before you start the treatment, but it is important you tell your doctor if you develop any of the following:

  • Any yellowing of your skin or of the whites of your eyes, or if you develop any stomach discomfort or pain that does not go away quickly. These can be signs that your liver is being affected.

  • If you feel very tired, start losing your appetite or weight, develop diarrhoea or sickness (vomiting), or feel particularly irritable or depressed. These can be signs that your adrenal glands are being affected.

Si vous ressentez d'autres symptômes que vous pensez être dus aux comprimés, veuillez consulter votre médecin ou votre pharmacien pour obtenir des conseils supplémentaires.

How to store cyproterone

  • Conservez tous les médicaments hors de la portée et de la vue des enfants.

  • Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.

Informations importantes sur tous les médicaments

Informations importantes sur tous les médicaments

Ne dépassez jamais la dose prescrite. Si vous pensez que vous ou quelqu'un d'autre avez pris une dose excessive de ce médicament, rendez-vous au service des accidents et des urgences de votre hôpital local. Emportez la boîte avec vous, même si elle est vide.

Ce médicament est pour vous. Ne le donnez pas à d'autres personnes, même si leur état semble être le même que le vôtre.

Si vous devez subir une opération ou un traitement dentaire, veuillez indiquer à la personne chargée du traitement les médicaments que vous prenez.

Si vous achetez des médicaments, vérifiez auprès d'un pharmacien qu'ils peuvent être pris avec vos autres médicaments.

Ne gardez pas les médicaments périmés ou dont vous ne voulez plus. Apportez-les à votre pharmacie locale qui les éliminera pour vous.

Si vous avez des questions sur ce médicament, demandez à votre pharmacien.

Signaler les effets secondaires d'un médicament ou d'un vaccin

Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne sur le site web de la carte jaune.

Autres lectures et références

Historique de l'article

Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.

  • Date de la prochaine révision : 13 juin 2027
  • 10 Jun 2024 | Dernière version

    Dernière mise à jour par

    Michael Stewart, MRPharmS

    Examiné par des pairs

    Sid Dajani
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