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Duloxétine pour les symptômes urinaires

Yentreve

The brand of duloxetine called Yentreve® is prescribed for women with stress incontinence. Take one capsule twice daily, in the morning and late afternoon. You may be given generic duloxetine capsules; 20 mg and 40 mg capsules are prescribed for stress incontinence.

Remember to do the exercises you have been given to strengthen your pelvic floor muscles.

Each time you collect a new supply of capsules, make sure the strength (20 mg or 40 mg) is the same as you have taken previously. If not, please speak with your pharmacist who will advise you.

En un coup d'œil

  • Duloxetine is a medicine used to treat symptoms of stress incontinence in women.

  • It is prescribed when pelvic floor exercises alone are not enough, or if surgery is not suitable.

  • It works by strengthening muscles around the bladder outlet to control urine flow.

  • You typically take one capsule twice daily, usually 40mg, but may start on a lower dose.

  • Common side effects include feeling sick, dry mouth, and constipation.

  • If you experience side effects or distressing thoughts, speak to your doctor immediately.

About duloxetine for urinary symptoms

Type de médicament

A serotonin and noradrenaline reuptake inhibitor

Utilisé pour

Symptoms of stress incontinence in women

Aussi appelé

Yentreve®

Disponible sous forme de

Capsules

Incontinence urinaire d'effort is the most common form of incontinence. It means you pass urine with things like coughing, sneezing or exercise. It happens when the pelvic floor muscles that support your bladder are weakened. Childbirth is a common reason for a weak pelvic floor. The main treatment for stress incontinence is pelvic floor exercises. Surgery to tighten or support your bladder outlet can also help.

Duloxetine may be advised if pelvic floor exercises alone are not helping to treat your stress incontinence. It is usually advised in women who do not want to undergo surgery, or in women who have health problems that may mean that surgery is unsuitable.

Duloxetine is thought to work by interfering with certain chemicals (called serotonin and noradrenaline) that are used within the nerves that send messages to your pelvic floor muscles. This helps the muscles around the bladder outlet to contract more strongly, and this in turn controls the flow of urine and helps to prevent any leakage.

Duloxetine is also prescribed for the treatment of some mood and nerve disorders, although a different brand and strength of capsule are used. There is a separate medicine leaflet called Duloxétine pour les troubles de l'humeur et nerveux which gives more information about duloxetine when it is used for this type of condition.

Before taking duloxetine

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking duloxetine it is important that your doctor knows:

  • Si vous êtes enceinte, essayez d'avoir un bébé ou allaitez.

  • Si vous avez des problèmes avec le fonctionnement de votre foie, ou des problèmes avec le fonctionnement de vos reins.

  • Si vous avez une maladie cardiaque.

  • If you have increased eye pressure (called glaucoma).

  • Si vous avez de l'hypertension.

  • If you have ever had 'high' moods, such as mania in bipolar disorder.

  • Si vous avez déjà eu une crise (convulsion).

  • If you have a blood disorder that increases your risk of bleeding.

  • Si vous prenez ou utilisez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et complémentaires.

  • Si vous avez déjà eu une réaction allergique à un médicament.

How to take duloxetine

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about duloxetine and will provide you with a full list of the side-effects which you may experience from taking it.

  • Take duloxetine exactly as your doctor tells you to. The usual dose is one 40 mg capsule twice daily (in the morning and late afternoon). If you are taking duloxetine for the first time, your doctor may give you the lower 20 mg strength capsule for a couple of weeks - this is to help avoid any unwanted symptoms when you first take duloxetine.

  • Try to take your doses at the same times of day each day, as this will help you to remember to take your doses regularly. You can take duloxetine either before or after meals. Take the capsules with a drink of water to help you to swallow.

  • If you forget to take a dose at your usual time, take it when you remember. However, if it is nearly time to take your next dose when you remember then leave out the forgotten dose and take your next dose when it is due. Do not take two doses together to make up for a missed dose.

Tirer le meilleur parti de votre traitement

  • Essayez de respecter vos rendez-vous réguliers avec votre médecin. Cela permet à votre médecin de suivre vos progrès et de revoir votre traitement.

  • Remember to do the exercises you have been given to strengthen your pelvic floor muscles. This is important because the majority of people with stress incontinence are much improved with these exercises.

  • If you have been advised to reduce your weight, try to stick to the advice you have been given about your diet. Losing even a modest amount of weight can help to improve your symptoms.

  • Smoking can cause coughing which can aggravate your symptoms. It would help to not smoke. If you are a smoker and you need help to quit, ask your doctor or pharmacist for advice.

  • Drinking alcohol can increase the risk of unwanted effects from duloxetine, such as dizziness and blurred vision.

  • If you buy any medicines, check with a pharmacist that they are suitable to take with duloxetine. This is because some herbal medicines (such as St John's wort) can increase the chance that you will experience unwanted effects.

  • If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking duloxetine.

  • Keep taking duloxetine until your doctor tells you otherwise. Stopping suddenly can cause problems and your doctor may want you to reduce your dose gradually when this becomes necessary.

Can duloxetine cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the common ones associated with duloxetine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common duloxetine side-effects (these affect more than 1 in 10 people)

Que puis-je faire si je ressens cela ?

Sensation de malaise (nausée)

Mangez des repas simples - évitez les aliments riches ou épicés

Bouche sèche

Essayez de mâcher du chewing-gum sans sucre ou de sucer des bonbons sans sucre

Constipation

Essayez de manger un régime équilibré et de boire plusieurs verres d'eau chaque jour

Common duloxetine side-effects (these affect fewer than 1 in 10 people)

Que puis-je faire si je ressens cela ?

Blurred vision, feeling tired, dizzy or sleepy

Do not drive and do not use tools or machines while affected. Avoid alcohol

Diarrhée

Buvez beaucoup d'eau pour remplacer les fluides perdus

Maux de tête

Ensure you are drinking the recommended amount of fluids each day. Ask your pharmacist to recommend a suitable painkiller. If the headaches continue, let your doctor know

Lack of appetite, indigestion, stomach pain, flushing, increased blood pressure, difficulty sleeping, feeling anxious, skin tinglings, feeling shaky, reduced interest in sex, increased sweating

Discutez-en avec votre médecin si l'un d'eux devient gênant

Important : if you develop any depressing or distressing thoughts or ideas, you should let your doctor know about this as soon as possible. When this medicine is prescribed for people with depression or anxiety, it can increase the risk of suicidal thoughts, particularly when the treatment is first started.

Dans de rares cas, des médicaments qui affectent le niveau de sérotonine dans le cerveau peuvent le faire augmenter excessivement et provoquer des problèmes. Le risque est plus élevé si vous prenez un autre médicament ayant cet effet (comme un antidépresseur). Consultez un médecin si vous développez l'une des combinaisons suivantes :

  • Muscles raides ou mouvements 'saccadés'.

  • Rythme cardiaque inhabituellement rapide.

  • Température élevée (fièvre).

  • Se sentir mal (nausée) ou vomir, diarrhée.

  • Se sentir délirant ou voir des visions (halluciner).

Si vous ressentez d'autres symptômes que vous pensez être dus aux capsules, veuillez consulter votre médecin ou votre pharmacien pour obtenir des conseils supplémentaires.

How to store duloxetine

  • Gardez tous les médicaments hors de la portée et de la vue des enfants.

  • Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.

Informations importantes sur tous les médicaments

Informations importantes sur tous les médicaments

Ne prenez jamais plus que la dose prescrite. Si vous soupçonnez que vous ou quelqu'un d'autre avez pris une surdose de ce médicament, rendez-vous au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.

Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.

Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.

Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.

Signaler les effets secondaires d'un médicament ou d'un vaccin

Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Site web de Yellow Card.

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Vous n'êtes pas sûr de mélanger des médicaments ?

Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.

Questions fréquemment posées

Can I take duloxetine if I am already taking other medications?

It is important to inform your doctor about all other medicines you are currently taking, including those bought without a prescription, and herbal or complementary medicines. Some medicines may not be suitable to take with duloxetine, or may require extra care.

What should I do if I forget to take a dose of duloxetine?

If you forget a dose at your usual time, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and just take your next dose when it is due. Never take two doses together to make up for a forgotten dose.

How long will I need to take duloxetine for my stress incontinence?

You should continue taking duloxetine until your doctor advises you to stop. When stopping, your doctor may suggest reducing your dose gradually instead of stopping suddenly to avoid potential problems.

Are there any specific lifestyle changes that can help improve my stress incontinence while taking duloxetine?

Yes, several lifestyle changes can help. It's important to continue performing any pelvic floor exercises you've been given. If you've been advised to lose weight, doing so, even a modest amount, can help. Quitting smoking can also reduce coughing, which might aggravate symptoms. Additionally, limiting alcohol intake can help prevent unwanted side-effects like dizziness and blurred vision while on duloxetine.

What happens if I need an operation or dental work while taking duloxetine?

If you are scheduled for an operation or dental treatment, you should inform the healthcare professional carrying out the treatment that you are taking duloxetine.

Lectures complémentaires et références

À propos de l'auteurVoir la biographie complète

Image de l'auteur

Michael Stewart, MRPharmS

Responsable de l'examen des notices de médicaments – Contractuel, Pharmacien

BPharm (Hons), MRPharmS

Michael est un pharmacien communautaire exerçant dans les Midlands et le South Yorkshire avec plus de 20 ans d'expérience dans le conseil sur les médicaments et les conditions médicales. Il possède une solide expérience en formation dans le domaine de la santé, ayant produit et dispensé des cours de formation pour les équipes de pharmacie et le personnel des établissements de soins résidentiels, y compris les infirmières. Il a également contribué aux comités consultatifs de pharmacie pour la gestion des affections de faible gravité dans la communauté.

À propos du critique

Image de l'auteur

Sid Dajani

Sultan Dajani a obtenu son diplôme à la London School of Pharmacy en 1994 et est devenu le plus jeune membre élu du conseil de la Royal Pharmaceutical Society depuis sa fondation en 1842.

Historique de l'article

Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.

  • Prochaine révision prévue : 24 août 2027
  • 23 août 2024 | Dernière version

    Dernière mise à jour par

    Michael Stewart, MRPharmS

    Revu par

    Sid Dajani
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