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Duloxetine pour les symptômes urinaires

Yentreve

The brand of duloxetine called Yentreve® is prescribed for women with stress incontinence. Take one capsule twice daily, in the morning and late afternoon. You may be given generic duloxetine capsules; 20 mg and 40 mg capsules are prescribed for stress incontinence.

Remember to do the exercises you have been given to strengthen your pelvic floor muscles.

Each time you collect a new supply of capsules, make sure the strength (20 mg or 40 mg) is the same as you have taken previously. If not, please speak with your pharmacist who will advise you.

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About duloxetine for urinary symptoms

Type de médicament

A serotonin and noradrenaline reuptake inhibitor

Utilisé pour

Symptoms of stress incontinence in women

Également appelé

Yentreve®

Disponible en

Capsules

Stress incontinence is the most common form of incontinence. It means you pass urine with things like coughing, sneezing or exercise. It happens when the pelvic floor muscles that support your bladder are weakened. Childbirth is a common reason for a weak pelvic floor. The main treatment for stress incontinence is pelvic floor exercises. Surgery to tighten or support your bladder outlet can also help.

Duloxetine may be advised if pelvic floor exercises alone are not helping to treat your stress incontinence. It is usually advised in women who do not want to undergo surgery, or in women who have health problems that may mean that surgery is unsuitable.

Duloxetine is thought to work by interfering with certain chemicals (called serotonin and noradrenaline) that are used within the nerves that send messages to your pelvic floor muscles. This helps the muscles around the bladder outlet to contract more strongly, and this in turn controls the flow of urine and helps to prevent any leakage.

Duloxetine is also prescribed for the treatment of some mood and nerve disorders, although a different brand and strength of capsule are used. There is a separate medicine leaflet called Duloxetine for mood and nerve disorders which gives more information about duloxetine when it is used for this type of condition.

Before taking duloxetine

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking duloxetine it is important that your doctor knows:

  • Si vous êtes enceinte, si vous essayez d'avoir un enfant ou si vous allaitez.

  • Si vous avez des problèmes de fonctionnement du foie ou des reins.

  • Si vous souffrez d'une maladie cardiaque.

  • If you have increased eye pressure (called glaucoma).

  • Si vous souffrez d'hypertension artérielle.

  • If you have ever had 'high' moods, such as mania in bipolar disorder.

  • If you have ever had a fit (seizure).

  • If you have a blood disorder that increases your risk of bleeding.

  • Si vous prenez ou utilisez d'autres médicaments. Cela comprend tous les médicaments que vous prenez et qui sont disponibles sans ordonnance, ainsi que les médicaments à base de plantes et les médicaments complémentaires.

  • Si vous avez déjà eu une réaction allergique à un médicament.

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How to take duloxetine

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about duloxetine and will provide you with a full list of the side-effects which you may experience from taking it.

  • Take duloxetine exactly as your doctor tells you to. The usual dose is one 40 mg capsule twice daily (in the morning and late afternoon). If you are taking duloxetine for the first time, your doctor may give you the lower 20 mg strength capsule for a couple of weeks - this is to help avoid any unwanted symptoms when you first take duloxetine.

  • Try to take your doses at the same times of day each day, as this will help you to remember to take your doses regularly. You can take duloxetine either before or after meals. Take the capsules with a drink of water to help you to swallow.

  • Si vous oubliez de prendre une dose à l'heure habituelle, prenez-la lorsque vous vous en apercevez. Cependant, s'il est presque temps de prendre la dose suivante lorsque vous vous en souvenez, laissez tomber la dose oubliée et prenez la dose suivante à l'heure prévue. Ne prenez pas deux doses en même temps pour compenser une dose oubliée.

Tirer le meilleur parti de votre traitement

  • Essayez de vous rendre à vos rendez-vous réguliers avec votre médecin. Il pourra ainsi vérifier vos progrès et revoir votre traitement.

  • Remember to do the exercises you have been given to strengthen your pelvic floor muscles. This is important because the majority of people with stress incontinence are much improved with these exercises.

  • If you have been advised to reduce your weight, try to stick to the advice you have been given about your diet. Losing even a modest amount of weight can help to improve your symptoms.

  • Smoking can cause coughing which can aggravate your symptoms. It would help to not smoke. If you are a smoker and you need help to quit, ask your doctor or pharmacist for advice.

  • Drinking alcohol can increase the risk of unwanted effects from duloxetine, such as dizziness and blurred vision.

  • If you buy any medicines, check with a pharmacist that they are suitable to take with duloxetine. This is because some herbal medicines (such as St John's wort) can increase the chance that you will experience unwanted effects.

  • If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking duloxetine.

  • Keep taking duloxetine until your doctor tells you otherwise. Stopping suddenly can cause problems and your doctor may want you to reduce your dose gradually when this becomes necessary.

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Can duloxetine cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the common ones associated with duloxetine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common duloxetine side-effects (these affect more than 1 in 10 people)

Que puis-je faire si je suis confronté à cette situation ?

Sensation de malaise (nausée)

Manger des repas simples - éviter les aliments riches ou épicés

Bouche sèche

Essayez de mâcher du chewing-gum sans sucre ou de sucer des bonbons sans sucre.

Constipation

Essayez d'avoir une alimentation équilibrée et buvez plusieurs verres d'eau par jour.

Common duloxetine side-effects (these affect fewer than 1 in 10 people)

Que puis-je faire si je suis confronté à cette situation ?

Blurred vision, feeling tired, dizzy or sleepy

Do not drive and do not use tools or machines while affected. Avoid alcohol

Diarrhée

Boire beaucoup d'eau pour remplacer les liquides perdus

Maux de tête

Ensure you are drinking the recommended amount of fluids each day. Ask your pharmacist to recommend a suitable painkiller. If the headaches continue, let your doctor know

Lack of appetite, indigestion, stomach pain, flushing, increased blood pressure, difficulty sleeping, feeling anxious, skin tinglings, feeling shaky, reduced interest in sex, increased sweating

Discutez-en avec votre médecin si l'un d'entre eux devient gênant.

Important: if you develop any depressing or distressing thoughts or ideas, you should let your doctor know about this as soon as possible. When this medicine is prescribed for people with depression or anxiety, it can increase the risk of suicidal thoughts, particularly when the treatment is first started.

On rare occasions, medicines that affect the level of serotonin in the brain can cause it to go too high and cause problems. The risk is higher if you are taking another medicine with this effect (such as an antidepressant). Seek medical attention if you develop any combination of the following:

  • Raideur musculaire ou mouvements saccadés.

  • Rythme cardiaque anormalement rapide.

  • Température élevée (fièvre).

  • Feeling sick (nausea) or being sick (vomiting), diarrhoea.

  • Sensation de délire ou visions (hallucinations).

If you experience any other symptoms which you think may be due to the capsules, please speak with your doctor or pharmacist for further advice.

How to store duloxetine

  • Conservez tous les médicaments hors de la portée et de la vue des enfants.

  • Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.

Informations importantes sur tous les médicaments

Informations importantes sur tous les médicaments

Ne dépassez jamais la dose prescrite. Si vous pensez que vous ou quelqu'un d'autre avez pris une dose excessive de ce médicament, rendez-vous au service des accidents et des urgences de votre hôpital local. Emportez la boîte avec vous, même si elle est vide.

Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.

Ne gardez pas les médicaments périmés ou dont vous ne voulez plus. Apportez-les à votre pharmacie locale qui les éliminera pour vous.

Si vous avez des questions sur ce médicament, demandez à votre pharmacien.

Signaler les effets secondaires d'un médicament ou d'un vaccin

Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne sur le site web de la carte jaune.

Autres lectures et références

Historique de l'article

Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.

  • Next review due: 24 Aug 2027
  • 23 Aug 2024 | Dernière version

    Dernière mise à jour par

    Michael Stewart, MRPharmS

    Examiné par des pairs

    Sid Dajani
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