Pommade rectale de trinitrate de glycéryle
Rectogesic
Revu par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSDernière mise à jour 20 oct. 2024
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Glyceryl trinitrate rectal ointment can ease the pain associated with small tears of skin around the back passage (anal fissures).
Use the ointment twice daily at 12-hourly intervals. You can use it for up to eight weeks if necessary.
The most common side-effect is a headache.
Dans cet article:
Sélections de vidéos pour Analgésiques et médicaments contre la douleur
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About glyceryl trinitrate rectal ointment
Type de médicament | A nitrate |
Utilisé pour | Pain relief for anal fissures (in adults) |
Aussi appelé | Nitroglycerin (in US); Rectogesic® |
Disponible sous forme de | Rectal ointment |
Une anal fissure is a small tear of the skin around your back passage (anus). Glyceryl trinitrate (GTN) rectal ointment (Rectogesic®) works by relaxing the muscle just inside your back passage. Relaxing this muscle increases the flow of blood to the area, which eases pain. It can be helpful where other treatments have not been effective.
A different brand of glyceryl trinitrate ointment (Percutol®) is used to relieve angina pain. For information on this product please see our medicine leaflet Trinitrate de glycéryle pour l'angine de poitrine.
Before using glyceryl trinitrate rectal ointment
Retour au sommaireTo make sure that this is the right treatment for you, before you start using GTN rectal ointment it is important that your doctor knows:
Si vous êtes enceinte ou si vous allaitez.
Si vous avez des problèmes avec le fonctionnement de votre foie, ou des problèmes avec le fonctionnement de vos reins.
If you have migraines or severe headaches.
If you have low blood pressure, or a heart condition.
If you have been told by a doctor you have low levels of iron in your blood (anaemia), or low levels of oxygen in your blood (hypoxaemia).
Si vous avez une glande thyroïde sous-active.
If you have an eye condition called glaucoma.
If you have recently had a head injury or a heart attack.
Si vous avez déjà eu une réaction allergique à un médicament.
If you are taking other medicines, including those available to buy without a prescription, as well as herbal or complementary medicines. It is particularly important that you tell your doctor if you are using any medicines to help treat erectile dysfunction.
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How to use glyceryl trinitrate rectal ointment
Retour au sommaireBefore you use the ointment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about using the ointment, and it will also provide you with a full list of side-effects which you could experience.
Cover your finger with a finger cot (available from pharmacies), or a piece of cling film, or use a disposable glove. Then measure out 2.5 cm of the ointment from the tube on to your finger (there is a measuring line on the packaging to help you). Then, using your finger, gently insert the ointment just inside your back passage. To make sure that the ointment gets to the correct place, insert your finger to the first finger joint. Apply the ointment this way every 12 hours until the pain goes away. You can continue to use the ointment for up to eight weeks, if needed.
Tirer le meilleur parti de votre traitement
Retour au sommaireRemember to follow any lifestyle or dietary advice you have been given by your doctor. Try to avoid becoming constipated, by eating a high-fibre diet and drinking several glasses of water each day.
It is best not to drink alcohol while you are using GTN rectal ointment. Alcohol will increase the chance that you experience side-effects such as feeling dizzy and light-headed.
If you experience any bleeding from your back passage, or if your symptoms do not improve, you should discuss this with your doctor.
If you buy any medicines, check with a pharmacist that they are suitable for you to take while you are using GTN rectal ointment.
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Can glyceryl trinitrate rectal ointment cause problems?
Retour au sommaireAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with GTN rectal ointment. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Very common glyceryl trinitrate rectal ointment side-effects (these affect more than 1 in 10 people) | Que puis-je faire si je ressens cela ? |
Maux de tête | Ask your pharmacist to recommend a suitable painkiller. If the headache is severe or if it continues, please ask your doctor for further advice |
Common glyceryl trinitrate rectal ointment side-effects (these affect fewer than 1 in 10 people) | Que puis-je faire si je ressens cela ? |
Se sentir étourdi ou avoir des vertiges | Ne conduisez pas et n'utilisez pas d'outils ou de machines lorsque vous êtes affecté |
Sensation de malaise (nausée) | Try to stick to simple meals (avoid rich or spicy foods). If it becomes troublesome, please speak with your doctor |
Less common glyceryl trinitrate rectal ointment side-effects | Que puis-je faire si je ressens cela ? |
Blurred vision, diarrhoea, local burning or itching | If any become troublesome, please speak with your doctor |
If you experience any other symptoms which you think may be due to the ointment, please speak with your doctor or pharmacist for further advice.
How to store glyceryl trinitrate rectal ointment
Retour au sommaireOnce opened, do not store or use the ointment for longer than eight weeks.
Gardez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.
Informations importantes sur tous les médicaments
Retour au sommaireInformations importantes sur tous les médicaments
Never use more than the prescribed dose. If you suspect that someone might have swallowed some of the ointment by accident, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
If you are having an operation or dental treatment, please remember to tell the person carrying out the treatment which medicines you are taking/using.
Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.
Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le site web Yellow Card.

Vous n'êtes pas sûr de mélanger des médicaments ?
Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.
Lectures complémentaires et références
- Manufacturer's PIL, Rectogesic® 4 mg/g Rectal Ointment; Grunenthal Meds, Kyowa Kirin International UK NewCo Ltd, The electronic Medicines Compendium. Dated February 2024.
- Médicaments Complets BNF 89e Édition; Association Médicale Britannique et Société Royale Pharmaceutique de Grande-Bretagne, Londres.
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Historique de l'article
Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.
Prochaine révision prévue : 16 oct. 2027
20 oct. 2024 | Dernière version

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