Lorazépam - une benzodiazépine
Revu par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSDernière mise à jour 15 sept 2022
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Lorazepam has a calming effect. It is prescribed for several different conditions.
Votre traitement sera aussi court que possible. Il peut aller d'une seule dose à un maximum de quatre semaines de traitement.
Lorazepam is likely to affect your reactions and ability to drive. These effects can last into the following day. It is an offence to drive while your reactions are impaired.
Do not drink alcohol while you are on lorazepam.
About lorazepam
Type de médicament | Une benzodiazépine |
Utilisé pour | Anxiety; insomnia associated with anxiety; as pre-medication before surgery or medical procedures; acute panic attacks; convulsions |
Disponible sous forme de | Comprimés, médicament liquide oral et injection |
Lorazepam works by affecting the way certain substances in your brain (called neurotransmitters) pass messages to your brain cells. It has a calming effect on various functions of your brain.
The calming effect is helpful in a variety of conditions which can be caused by anxiété, such as panic attacks and difficulties sleeping. The calming effect is also used to relax and/or sedate people who are having certain medical investigations or treatments. It is given as a pre-med, particularly during procedures that can cause anxiety or discomfort. The calming action also helps to relax muscles, so lorazepam injection is used to treat fits, such as those caused by epilepsy.
Before taking lorazepam
Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking lorazepam it is important that your doctor knows:
Si vous êtes enceinte ou si vous allaitez.
Si vous avez des problèmes respiratoires.
Si vous avez des problèmes avec le fonctionnement de votre foie, ou si vous avez des problèmes avec le fonctionnement de vos reins.
Si vous avez un problème de santé mentale. Cela inclut des conditions telles que la psychose, la dépression, les troubles obsessionnels, les phobies et les troubles de la personnalité.
Si vous avez déjà eu une dépendance à la drogue ou à l'alcool.
Si vous avez une affection provoquant une faiblesse musculaire sévère, appelée myasthénie grave.
Si vous avez déjà eu une réaction allergique à un médicament.
Si vous prenez ou utilisez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et les médecines complémentaires.
How to take lorazepam
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about lorazepam, and will also provide you with a full list of the side-effects which you could experience from taking it.
Take lorazepam exactly as your doctor tells you to - the dose will be individualised to suit your needs. The directions for taking the tablets will be printed on the label of the pack to remind you about what the doctor said to you. You could be asked to take just one single dose (if it is before a medical procedure, for example), or to take regular doses for a short while. If you are to take lorazepam regularly for anxiety, you will probably be prescribed two or three doses to take a day. If you are taking it because you are having difficulty sleeping, you will be prescribed a dose to take at bedtime only. The course of treatment prescribed will be as short as possible. If you have any questions about how to take the tablets, please ask your doctor or pharmacist for further advice.
Try to take your doses of lorazepam at the same times of day each day, as this will help you to remember to take them. Swallow the tablet(s) with a drink of water. You can take lorazepam either with or without food.
If you forget to take a dose at the usual time, take it when you remember. Try to take the correct number of doses each day, but do not take two doses together to make up for a forgotten dose.
Tirer le meilleur parti de votre traitement
Remember to keep any follow-up appointments with your doctor. This is so your doctor can check on your progress.
Lorazepam is likely to affect your reactions and ability to drive. It is an offence to drive while your reactions are impaired. Do not drive until you know how you react, especially when you first start treatment. Please also be aware that the effects of lorazepam can last into the following day. Even if your driving ability is not impaired, should you drive, you are advised to carry with you some evidence that the medicine has been prescribed for you - a repeat prescription form or a patient information leaflet from the pack is generally considered suitable.
You should not drink alcohol while you are on lorazepam. It will increase the risk of sedative side-effects.
Lorazepam is taken for short periods of time only, often for just a few days. It will not be for longer than four weeks, as this may lead to you feeling dependent on it. Also, your body gets used to it quickly, and after this time it is unlikely to have the same effect.
It is possible that drinking grapefruit juice can increase the amount of lorazepam in your bloodstream, which may increase the risk of side-effects. It is probably best to avoid drinking grapefruit juice while you are taking lorazepam.
If you are due to have an operation or any dental treatment, please tell the person carrying out the treatment that you are taking lorazepam. This is because lorazepam increases the effects of some anaesthetics.
Your doctor could recommend that you reduce your dose of lorazepam gradually when it is time to stop taking it. This is to reduce the risk of you experiencing withdrawal effects. Follow carefully any instructions your doctor gives to you.
Can lorazepam cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the more common ones associated with lorazepam. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common lorazepam side-effects | Que puis-je faire si je ressens cela ? |
Se sentir somnolent, faible ou étourdi (ces sensations peuvent persister le jour suivant) | Ne conduisez pas et n'utilisez pas d'outils ou de machines. Ne buvez pas d'alcool |
Oubli, sensation de confusion ou d'instabilité | Si l'un de ces éléments devient problématique, parlez-en à votre médecin |
Se sentir (ou être) agressif | Cela peut arriver chez certaines personnes - informez-en votre médecin dès que possible |
Si vous ressentez d'autres symptômes que vous pensez être dus au médicament, parlez-en à votre médecin ou à votre pharmacien pour obtenir des conseils supplémentaires.
How to store lorazepam
Gardez tous les médicaments hors de la vue et de la portée des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur directe et de la lumière.
Informations importantes sur tous les médicaments
Informations importantes sur tous les médicaments
Ne prenez jamais plus que la dose prescrite. Si vous soupçonnez que vous ou quelqu'un d'autre avez pris une surdose de ce médicament, rendez-vous au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Si vous achetez des médicaments, vérifiez avec un pharmacien qu'ils sont sans danger à prendre avec vos autres médicaments.
Ne conservez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.
Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Site web de Yellow Card.
Questions fréquemment posées
How quickly does lorazepam work?
The article states that lorazepam has a calming effect, which is helpful for various conditions like panic attacks and sleep difficulties. It's also used to relax or sedate people during medical procedures. However, the precise onset time of its effects is not detailed.
Is 1 mg of lorazepam a low dose?
The article mentions that the dose of lorazepam will be individualised to suit your needs and that you should take it exactly as your doctor tells you to. It does not specify what constitutes a low, medium, or high dose.
What is lorazepam?
Lorazepam is a type of medicine known as a benzodiazepine. It works by affecting particular substances in the brain, called neurotransmitters, which are responsible for sending messages between brain cells. This action produces a calming effect on various brain functions.
What does lorazepam do?
Lorazepam has a calming effect on the brain. This can help with anxiety, insomnia associated with anxiety, and acute panic attacks. It is also used as a pre-medication to relax or sedate people before surgery or specific medical procedures, and its calming action also helps relax muscles, making it useful in treating convulsions like those caused by epilepsy.
Is lorazepam a benzodiazepine?
Yes, lorazepam is categorised as a benzodiazepine. This is mentioned at the beginning of the article under the 'Type of medicine' section.
Lectures complémentaires et références
- Manufacturer's PIL, Lorazepam 1 mg and 2.5 mg Tablets; Genus Pharmaceuticals, The electronic Medicines Compendium. Dated July 2020.
- Médicaments Complets BNF 89e Édition; Association Médicale Britannique et Société Royale Pharmaceutique de Grande-Bretagne, Londres.
À propos du critique

Sid Dajani
Sultan Dajani a obtenu son diplôme à la London School of Pharmacy en 1994 et est devenu le plus jeune membre élu du conseil de la Royal Pharmaceutical Society depuis sa fondation en 1842.
Historique de l'article
Article également disponible en Anglais, Allemand, Espagnol, Français, Italien, Portugais, Hindi, Hébreu, Arabe, and Suédois.
Prochaine révision prévue : 13 mars 2027
15 sept 2022 | Dernière version
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