Phénoxybenzamine - un alpha-bloquant

About phenoxybenzamine

Phaeochromocytoma is a tumour of your adrenal glands. With phaeochromocytoma, large quantities of chemicals are released from your adrenal glands, which narrow (constrict) your blood vessels. This causes episodes where your blood pressure increases significantly.

The treatment of choice for phaeochromocytoma is removal of the tumour by surgery. Phenoxybenzamine is sometimes prescribed as a short-term option in preparation for the surgery. It works by blocking sites on your blood vessels, known as alpha receptors. This blocking action reduces your l'hypertension artérielle.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking phenoxybenzamine it is important that your doctor knows:

• Si vous êtes enceinte ou si vous allaitez.

• If you have problems with the way your kidneys work.

• If you have heart disease, or if you have recently had a heart attack.

• If you have ever had a stroke.

• Si vous avez un trouble sanguin héréditaire rare appelé porphyrie.

• Si vous avez déjà eu une réaction allergique à un médicament.

• Si vous prenez ou utilisez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et complémentaires.

• Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about phenoxybenzamine, and will also provide you with a full list of side-effects which you could experience from taking it.

• When you start the treatment, your doctor will give you a small dose (one capsule a day) and will then gradually increase your dose over the next few days as necessary. Take phenoxybenzamine capsules exactly as your doctor tells you to. The directions will be printed on the label of the pack of capsules to remind you about what the doctor said to you.

• Try to take your doses at the same time of day each day, as this will help you to remember to take them regularly. You can take phenoxybenzamine either before or after a meal. Swallow the capsule with a drink of water.

• If you forget to take a dose at your usual time, take it as soon as you remember. If you do not remember until the following day, leave out the forgotten dose from the previous day and take the dose that is due as normal. Do not take two doses at the same time to make up for a missed dose.

• Gardez vos rendez-vous réguliers avec votre médecin. Cela permet à votre médecin de suivre vos progrès.

• If you buy any medicines, check with a pharmacist that they are suitable for you to take alongside phenoxybenzamine.

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains the most common ones associated with phenoxybenzamine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any continue or become troublesome.

Si vous ressentez d'autres symptômes que vous pensez être dus aux capsules, consultez votre médecin ou votre pharmacien pour obtenir des conseils supplémentaires.

• Gardez tous les médicaments hors de la portée et de la vue des enfants.

• Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.