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Podophyllotoxine pour les verrues anogénitales

Warticon

Carefully follow the instructions from the pack for applying podophyllotoxin.

Wash your hands thoroughly after each application.

Do not use podophyllotoxin if you think you could be pregnant.

En un coup d'œil

  • Podophyllotoxin is a plant extract used to treat anogenital warts.

  • It works by stopping wart cells from dividing, allowing new healthy tissue to grow.

  • Apply it twice daily for three days, then take four days off, repeating for up to 4-5 weeks.

  • Avoid applying to broken skin, and wash hands thoroughly after use.

  • Local irritation like redness or itching is a common side-effect.

  • If irritation is severe, or the area bleeds, stop use and consult your doctor.

About podophyllotoxin

Type de médicament

A plant extract for removing warts

Utilisé pour

Verrues anogénitales

Aussi appelé

Podofilox (in US); Warticon®

Disponible sous forme de

Cream and solution

You will have been prescribed podophyllotoxin to treat anogenital warts. Anogenital warts are caused by the human papillomavirus (HPV) which can be passed on by close sexual contact. They are small lumps that develop on the genitals and around the back passage (anus). Podophyllotoxin is a topical preparation which is applied directly to the surface of the wart. It works by preventing the wart cells from dividing, which stops them from increasing in number. As the wart cells die, new healthy tissue grows in their place.

Before using podophyllotoxin

To make sure this is the right treatment for you, before you start using podophyllotoxin it is important that your doctor knows:

  • Si vous êtes enceinte, essayez d'avoir un bébé ou allaitez.

  • If you have ever had an allergic reaction to podophyllotoxin.

How to use podophyllotoxin

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack and any additional information you are given by your doctor. These will give you more information about how to use podophyllotoxin and will provide you with a full list of the side-effects which you may experience from using it.

  • Follow the instructions carefully when you are applying the cream/solution and do not apply more than the recommended amount. You will be asked to use the preparation twice daily (in the morning and the evening) for three consecutive days. This is then followed by four days without treatment. Your doctor is likely to ask you to repeat the three-day treatment followed by four days without treatment until the warts have gone, or alternatively for a total of 4-5 weeks.

  • Wash your hands and the area to be treated with mild soap and water before applying the podophyllotoxin. Make sure your skin is dry before you apply the cream/solution.

  • If you are using the solution, you will be given applicators to use. The applicator has an end with a 'loop' which allows you to treat individual warts. Dip the applicator into the bottle so that the hole is filled with solution, and then touch the wart with the applicator to transfer the solution to it. Allow the solution to dry. Some applicators have a 'spatula' end which is suitable for applying the solution to small collections of warts. If you are using the cream, apply it using a fingertip but remember to wash your hands thoroughly after each application.

  • Do not put podophyllotoxin on any area of skin which is raw or bleeding, and be careful to avoid getting it on the healthy areas of skin around the warts. It is only to be used on the outside (external) skin - do not apply it to the inside of the vagina, penis or back passage.

  • If the cream or solution comes into contact with any healthy areas of skin by accident, wash the area with water to remove it. Podophyllotoxin can be very irritant if any splashes get into the eyes by accident.

Tirer le meilleur parti de votre traitement

  • When you have anogenital warts you will usually be advised to have tests to check for other sexually transmitted infections. Your doctor or clinic will arrange these for you.

  • Sexual contact is not generally recommended while you are treating anogenital warts. You should ideally wait until your warts have gone and your skin has healed. If you do have sex, use a condom, as the warts can be passed to your partner and also the podophyllotoxin can cause irritation for your partner. It is also commonly advised that you use condoms for a time even after the warts have gone.

  • Never use wart treatments that are sold over-the-counter in pharmacies to treat your anogenital warts.

  • Solutions of podophyllotoxin are flammable. Do not use the solutions near a flame, and remember to keep the container closed when not in use.

Can podophyllotoxin cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with podophyllotoxin. You will find a full list in the manufacturer's information leaflet supplied with the cream/solution. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common podophyllotoxin side-effects (these affect more than 1 in 10 people)

Que puis-je faire si je ressens cela ?

Local irritation such as redness, itching, or burning

This typically occurs on the second or third day of application, but tends to be mild. If the area starts to bleed or becomes very painful, stop using the preparation and speak with your doctor for advice

If you experience any other symptoms which you think may be due to podophyllotoxin, discuss them with your doctor or pharmacist.

How to store podophyllotoxin

  • Gardez tous les médicaments hors de la portée et de la vue des enfants.

  • Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.

Informations importantes sur tous les médicaments

Informations importantes sur tous les médicaments

Make sure that the person supplying this medicine knows about any other medicines that you are using. This includes any medicines you have bought, including herbal and homeopathic medicines.

Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.

This preparation is for use on the skin only. If you suspect that someone has swallowed some of it, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.

Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.

If you are due to have an operation or any medical treatment, tell the person carrying out the treatment which medicines you are using.

Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.

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Questions fréquemment posées

What is HPV and how does it relate to anogenital warts?

Anogenital warts are caused by the human papillomavirus (HPV). This virus is typically spread through close sexual contact. Podophyllotoxin works by targeting the wart cells that result from HPV infection, preventing them from multiplying.

Are there any specific safety precautions I should take when applying podophyllotoxin?

Yes, you should be careful not to apply podophyllotoxin to any areas of skin that are raw or bleeding. Also, try to avoid getting the preparation on healthy skin around the warts. It is strictly for external use, so do not apply it inside the vagina, penis, or back passage. If any splashes get into your eyes, wash the area with water immediately.

What should I do if I accidentally get podophyllotoxin on healthy skin?

If the cream or solution accidentally comes into contact with healthy areas of your skin, wash the area with water to remove it. This helps to prevent irritation.

Why is it important to avoid sexual contact during treatment?

Sexual contact is generally not recommended while you are being treated for anogenital warts. This is because the warts can be passed to your partner. Additionally, the podophyllotoxin itself can cause irritation for your partner. It's usually advised to wait until your warts have cleared and your skin has healed before resuming sexual activity.

Can I use over-the-counter wart treatments on anogenital warts?

No, you should never use wart treatments sold over-the-counter in pharmacies for anogenital warts. Podophyllotoxin is a specific prescription treatment for this condition.

What should I do if I accidentally swallow podophyllotoxin?

If you suspect that someone has swallowed some of the product, you should go to the accident and emergency department of your local hospital immediately. Remember to take the container with you, even if it is empty, so medical staff know what has been ingested.

Is podophyllotoxin safe to use if I am pregnant or breastfeeding?

Before starting treatment, it's very important to inform your doctor if you are pregnant, trying for a baby, or breastfeeding. Your doctor needs this information to determine if podophyllotoxin is the right treatment for you.

Lectures complémentaires et références

À propos de l'auteurVoir la biographie complète

Image de l'auteur

Michael Stewart, MRPharmS

Responsable de l'examen des notices de médicaments – Contractuel, Pharmacien

BPharm (Hons), MRPharmS

Michael est un pharmacien communautaire exerçant dans les Midlands et le South Yorkshire avec plus de 20 ans d'expérience dans le conseil sur les médicaments et les conditions médicales. Il possède une solide expérience en formation dans le domaine de la santé, ayant produit et dispensé des cours de formation pour les équipes de pharmacie et le personnel des établissements de soins résidentiels, y compris les infirmières. Il a également contribué aux comités consultatifs de pharmacie pour la gestion des affections de faible gravité dans la communauté.

À propos du critique

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Sid Dajani

Sultan Dajani a obtenu son diplôme à la London School of Pharmacy en 1994 et est devenu le plus jeune membre élu du conseil de la Royal Pharmaceutical Society depuis sa fondation en 1842.

Historique de l'article

Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.

  • Next review due: 8 Nov 2026
  • 9 Nov 2023 | Dernière version

    Dernière mise à jour par

    Michael Stewart, MRPharmS

    Revu par

    Sid Dajani
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