Quinine pour le paludisme
Revu par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSDernière mise à jour 16 Jun 2024
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Quinine is prescribed to treat malaria in people who have been bitten by an infected mosquito. It is not suitable for preventing malaria.
Quinine is an ingredient of drinks such as tonic water and bitter lemon - try to avoid these while you are taking quinine tablets.
Contact a doctor immediately if anyone swallows quinine by accident, or if you take more than the prescribed dose.
En un coup d'œil
Quinine is a medicine used to treat the infection malaria.
Take quinine exactly as your doctor tells you, even if you feel better.
Tell your doctor if you have certain conditions, like heart or kidney problems, before taking quinine.
Common side-effects include diarrhoea, headache, and ringing in your ears.
Seek urgent medical help if you suspect an overdose or experience severe side-effects like breathing difficulties.
Keep quinine tablets out of reach of children.
About quinine for malaria
Type de médicament | Un médicament antipaludique |
Utilisé pour | To treat malaria |
Aussi appelé | Quinine bisulfate, quinine dihydrochloride, quinine sulfate |
Disponible sous forme de | Comprimés et injection |
Paludisme is a very serious infection which you can develop from a bite from an infected mosquito. The most common symptom is high temperature (fever) and a flu-like illness. Malaria can occur even up to a year after travelling in an area in which there is malaria. Prompt treatment for malaria is essential. If you feel unwell and have recently visited an area in which there is malaria, you should seek prompt medical advice, even if you have taken your antimalarial medication correctly.
Malaria is caused by a parasite called plasmodium. The parasite lives inside the stomach of an infected female mosquito and is passed to humans from a mosquito bite. There are four types of plasmodium that cause malaria. Of the four, Plasmodium falciparum is usually the most serious, so this type of malaria is likely to be treated in hospital.
Quinine is also used to treat night-time leg cramps. For information about this please see the medicine leaflet Quinine pour les crampes aux jambes.
Before taking quinine
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking quinine it is important that your doctor knows:
Si vous êtes enceinte ou si vous allaitez.
If you have any problems with your eyes, or with your hearing.
If you have a heart condition, such as an irregular heart rhythm.
Si vous avez des problèmes avec le fonctionnement de vos reins, ou des problèmes avec le fonctionnement de votre foie.
If you have blood in your urine.
If you have been told you have an imbalance of salt levels in your blood.
Si vous avez une affection provoquant une faiblesse musculaire, appelée myasthénie grave.
If you have glucose 6-phosphate dehydrogenase deficiency. This is a genetic disorder where there is a lack of an enzyme often known as G6PD. People with this disorder have problems after eating foods such as fava beans.
Si vous prenez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et les médecines complémentaires.
If you have ever had an allergic reaction to a medicine, or if you have had a bad reaction to quinine in tonic water or any other soft drink.
How to take quinine
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about quinine and will provide you with a full list of the side-effects which you may experience from taking it.
Take quinine exactly as your doctor tells you to. If you are being treated in hospital, your nurse will tell you when your tablets are due. If you are being treated at home, your doctor or pharmacist will tell you how many tablets to take for each dose, and when the doses should be taken. Your dose will also be printed on the label of the pack to remind you about what the doctor said to you. Space the doses evenly throughout the day and continue to take the tablets until the course is finished, unless your doctor tells you to stop sooner. It is important you do this even if you feel better. It is to make sure that all of the parasite has been removed from your body.
Swallow your doses with a drink of water. You can take quinine tablets either before or after meals.
If you forget to take a dose, take it as soon as you remember. Try to take the correct number of doses each day but do not take two doses at the same time to make up for a missed dose.
Tirer le meilleur parti de votre traitement
If you are being treated from home, make sure you keep your regular appointments with your doctor. This is so your doctor can check on your progress.
Your doctor will discuss with you the possibility of unwanted side-effects of the treatment. It is important that you let your doctor know, avant you take your next dose, if you experience any of the following: impaired hearing, ringing noises in your ear, headaches, feeling sick (nausea), or any problems with your eyesight.
Quinine is present in drinks such as tonic water and bitter lemon. It is probably best to avoid these drinks while you are taking quinine tablets.
Never take more than the prescribed dose. Taking too much quinine can cause serious problems. Also, quinine is dangerous if it is taken by a child, so keep the tablets away from children. If you suspect that someone has taken an overdose of quinine or has swallowed some by accident, you must contact a doctor immédiatement. Alternatively, go to the accident and emergency department of a local hospital. Ne tardez pas. Prenez le contenant avec vous, même s'il est vide. Cela permet au médecin de savoir ce qui a été pris.
If you buy any medicines, always check with a pharmacist that they are suitable to take with your other medicines. This is because some medicines (such as cimetidine which is taken for heartburn) can interfere with quinine and increase the risk of serious side-effects.
If you are being treated for diabetes, quinine can lower the level of sugar in your blood. Your doctor will be able to advise you about this.
Can quinine cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the side-effects associated with quinine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. Although unwanted effects often improve as your body adjusts to a new medicine, serious side-effects do still sometimes occur. Contact your doctor for advice as soon as possible if you experience any of the following:
Quinine side-effects | Que puis-je faire si je ressens cela ? |
Diarrhoea, feeling sick (nausea), feeling weak or confused, 'ringing' in your ears, headache, having a spinning sensation (vertigo) | Tell your doctor as soon as possible |
Vision problems, such as blurred vision and colour changes | Tell your doctor as soon as possible. Do not drive while your vision is affected |
Hot and flushed skin, rashes, muscle weakness, increased sensitivity to light | Si l'un d'eux devient gênant, informez-en votre médecin |
Difficulty breathing, swelling around your mouth or face | Parlez avec votre médecin immédiatement - these are signs of an allergy to quinine |
Unexplained bleeding, unusual bruising, sore throats or infections | Tell your doctor as soon as possible - these could be signs of a serious blood disorder and your doctor will want to check for this |
Si vous ressentez d'autres symptômes que vous pensez être dus aux comprimés, veuillez consulter votre médecin ou votre pharmacien pour obtenir des conseils supplémentaires.
How to store quinine
Gardez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.
Informations importantes sur tous les médicaments
Informations importantes sur tous les médicaments
Si vous subissez une opération ou un traitement dentaire, informez la personne effectuant le traitement des médicaments que vous utilisez.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.
Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Site web de Yellow Card.

Vous n'êtes pas sûr de mélanger des médicaments ?
Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.
Questions fréquemment posées
What is the primary difference between the types of malaria caused by the Plasmodium parasite?
There are four types of Plasmodium parasites that cause malaria. Among them, Plasmodium falciparum is generally considered the most severe type and often requires hospital treatment.
What should I do if I am traveling to a malaria-prone area and accidentally consume quinine from tonic water?
The article states that it is 'probably best to avoid' drinks containing quinine, like tonic water, while taking quinine tablets. It does not elaborate on accidental consumption while traveling to a malaria-prone area, but generally, if you are being treated for malaria with quinine, it's best to avoid additional sources of quinine.
How long does treatment with quinine typically last?
The article advises to 'continue to take the tablets until the course is finished, unless your doctor tells you to stop sooner'. It emphasises the importance of completing the full course, even if you feel better, to ensure all parasites are removed from your body. The specific duration of treatment is not specified and would be determined by your doctor.
Are there any specific foods I should avoid while taking quinine?
The article mentions that people with glucose 6-phosphate dehydrogenase deficiency, a genetic disorder, have problems after eating foods such as fava beans. If you have this deficiency, you should discuss this with your doctor before taking quinine. Otherwise, no specific foods are generally mentioned for avoidance.
Can quinine affect blood sugar levels, especially for individuals with diabetes?
Yes, if you are being treated for diabetes, quinine has the potential to lower your blood sugar level. Your doctor will be able to provide specific advice regarding this.
What should I do if I experience unusual bleeding or bruising while taking quinine?
If you experience unexplained bleeding, unusual bruising, sore throats, or infections, you should contact your doctor as soon as possible. These could be indicators of a serious blood disorder, and your doctor will want to check for this.
Lectures complémentaires et références
- Manufacturer's PIL, Quinine Sulfate Tablets 300 mg; Strides Pharma UK Ltd, The electronic Medicines Compendium. Dated May 2022.
- Médicaments Complets BNF 89e Édition; Association Médicale Britannique et Société Royale Pharmaceutique de Grande-Bretagne, Londres.
À propos de l'auteurVoir la biographie complète

Michael Stewart, MRPharmS
Responsable de l'examen des notices de médicaments – Contractuel, Pharmacien
BPharm (Hons), MRPharmS
Michael est un pharmacien communautaire exerçant dans les Midlands et le South Yorkshire avec plus de 20 ans d'expérience dans le conseil sur les médicaments et les conditions médicales. Il possède une solide expérience en formation dans le domaine de la santé, ayant produit et dispensé des cours de formation pour les équipes de pharmacie et le personnel des établissements de soins résidentiels, y compris les infirmières. Il a également contribué aux comités consultatifs de pharmacie pour la gestion des affections de faible gravité dans la communauté.
À propos du critique

Sid Dajani
Sultan Dajani a obtenu son diplôme à la London School of Pharmacy en 1994 et est devenu le plus jeune membre élu du conseil de la Royal Pharmaceutical Society depuis sa fondation en 1842.
Historique de l'article
Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.
Article également disponible en Anglais, Allemand, Espagnol, Français, Italien, Portugais, Hindi, Hébreu, Arabe, and Suédois.
Next review due: 16 Jun 2027
16 Jun 2024 | Dernière version

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