Quinine pour le paludisme
Peer reviewed by Sid DajaniLast updated by Michael Stewart, MRPharmSLast updated 16 Jun 2024
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Quinine is prescribed to treat malaria in people who have been bitten by an infected mosquito. It is not suitable for preventing malaria.
Quinine is an ingredient of drinks such as tonic water and bitter lemon - try to avoid these while you are taking quinine tablets.
Contact a doctor immediately if anyone swallows quinine by accident, or if you take more than the prescribed dose.
Dans cet article :
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About quinine for malaria
Type de médicament | An antimalarial medicine |
Utilisé pour | To treat malaria |
Également appelé | Quinine bisulfate, quinine dihydrochloride, quinine sulfate |
Disponible en | Comprimés et injections |
Malaria is a very serious infection which you can develop from a bite from an infected mosquito. The most common symptom is high temperature (fever) and a flu-like illness. Malaria can occur even up to a year after travelling in an area in which there is malaria. Prompt treatment for malaria is essential. If you feel unwell and have recently visited an area in which there is malaria, you should seek prompt medical advice, even if you have taken your antimalarial medication correctly.
Malaria is caused by a parasite called plasmodium. The parasite lives inside the stomach of an infected female mosquito and is passed to humans from a mosquito bite. There are four types of plasmodium that cause malaria. Of the four, Plasmodium falciparum is usually the most serious, so this type of malaria is likely to be treated in hospital.
Quinine is also used to treat night-time leg cramps. For information about this please see the medicine leaflet Quinine for leg cramps.
Before taking quinine
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking quinine it is important that your doctor knows:
Si vous êtes enceinte ou si vous allaitez.
If you have any problems with your eyes, or with your hearing.
If you have a heart condition, such as an irregular heart rhythm.
Si vous avez des problèmes de fonctionnement des reins ou du foie.
If you have blood in your urine.
If you have been told you have an imbalance of salt levels in your blood.
Si vous souffrez d'une maladie entraînant une faiblesse musculaire, appelée myasthénie grave.
If you have glucose 6-phosphate dehydrogenase deficiency. This is a genetic disorder where there is a lack of an enzyme often known as G6PD. People with this disorder have problems after eating foods such as fava beans.
Si vous prenez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles sans ordonnance, ainsi que les médicaments à base de plantes et les médicaments complémentaires.
If you have ever had an allergic reaction to a medicine, or if you have had a bad reaction to quinine in tonic water or any other soft drink.
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How to take quinine
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about quinine and will provide you with a full list of the side-effects which you may experience from taking it.
Take quinine exactly as your doctor tells you to. If you are being treated in hospital, your nurse will tell you when your tablets are due. If you are being treated at home, your doctor or pharmacist will tell you how many tablets to take for each dose, and when the doses should be taken. Your dose will also be printed on the label of the pack to remind you about what the doctor said to you. Space the doses evenly throughout the day and continue to take the tablets until the course is finished, unless your doctor tells you to stop sooner. It is important you do this even if you feel better. It is to make sure that all of the parasite has been removed from your body.
Swallow your doses with a drink of water. You can take quinine tablets either before or after meals.
Si vous oubliez de prendre une dose, prenez-la dès que vous vous en rendez compte. Essayez de prendre le nombre correct de doses chaque jour, mais ne prenez pas deux doses en même temps pour compenser une dose oubliée.
Tirer le meilleur parti de votre traitement
If you are being treated from home, make sure you keep your regular appointments with your doctor. This is so your doctor can check on your progress.
Your doctor will discuss with you the possibility of unwanted side-effects of the treatment. It is important that you let your doctor know, before you take your next dose, if you experience any of the following: impaired hearing, ringing noises in your ear, headaches, feeling sick (nausea), or any problems with your eyesight.
Quinine is present in drinks such as tonic water and bitter lemon. It is probably best to avoid these drinks while you are taking quinine tablets.
Never take more than the prescribed dose. Taking too much quinine can cause serious problems. Also, quinine is dangerous if it is taken by a child, so keep the tablets away from children. If you suspect that someone has taken an overdose of quinine or has swallowed some by accident, you must contact a doctor straightaway. Alternatively, go to the accident and emergency department of a local hospital. Do not delay. Take the container with you, even if it is empty. This is so the doctor knows what has been taken.
If you buy any medicines, always check with a pharmacist that they are suitable to take with your other medicines. This is because some medicines (such as cimetidine which is taken for heartburn) can interfere with quinine and increase the risk of serious side-effects.
If you are being treated for diabetes, quinine can lower the level of sugar in your blood. Your doctor will be able to advise you about this.
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Can quinine cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the side-effects associated with quinine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. Although unwanted effects often improve as your body adjusts to a new medicine, serious side-effects do still sometimes occur. Contact your doctor for advice as soon as possible if you experience any of the following:
Quinine side-effects | Que puis-je faire si je suis confronté à cette situation ? |
Diarrhoea, feeling sick (nausea), feeling weak or confused, 'ringing' in your ears, headache, having a spinning sensation (vertigo) | Tell your doctor as soon as possible |
Vision problems, such as blurred vision and colour changes | Tell your doctor as soon as possible. Do not drive while your vision is affected |
Hot and flushed skin, rashes, muscle weakness, increased sensitivity to light | Si l'un d'entre eux devient gênant, informez-en votre médecin. |
Difficulty breathing, swelling around your mouth or face | Parlez-en à votre médecin tout de suite - these are signs of an allergy to quinine |
Unexplained bleeding, unusual bruising, sore throats or infections | Tell your doctor as soon as possible - these could be signs of a serious blood disorder and your doctor will want to check for this |
Si vous ressentez d'autres symptômes que vous pensez être dus aux comprimés, veuillez consulter votre médecin ou votre pharmacien pour obtenir des conseils supplémentaires.
How to store quinine
Conservez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.
Informations importantes sur tous les médicaments
Informations importantes sur tous les médicaments
Si vous devez subir une opération ou un traitement dentaire, indiquez à la personne chargée du traitement les médicaments que vous utilisez.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Ne gardez pas les médicaments périmés ou dont vous ne voulez plus. Apportez-les à votre pharmacie locale qui les éliminera pour vous.
Si vous avez des questions sur ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne sur le site web de la carte jaune.
Autres lectures et références
- Manufacturer's PIL, Quinine Sulfate Tablets 300 mg; Strides Pharma UK Ltd, The electronic Medicines Compendium. Dated May 2022.
- Médicaments Complet BNF 89ème éditionBritish Medical Association et Royal Pharmaceutical Society of Great Britain, Londres.
Historique de l'article
Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.
Next review due: 16 Jun 2027
16 Jun 2024 | Dernière version

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