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Comprimés de ropinirole

Adartrel, Requip

There are several brands of ropinirole available and your treatment could be affected by switching between brands. Each time you collect a new supply of tablets from your pharmacy, please check to see if the tablets are the same as before. If they are different, discuss this with your pharmacist who will advise you.

Ropinirole could make you feel dizzy especially during the first few days of treatment. Get up more slowly until you know how you react.

Occasionally, people taking ropinirole (particularly when taken for Parkinson's disease) have fallen asleep suddenly during the day with little warning of being tired. If you experience this, please do not drive, and make an appointment to see your doctor as soon as possible. Ropinirole can also cause impulsive types of behaviour in some people.


At a glance

  • Ropinirole is a medicine for Parkinson's disease and restless legs syndrome.

  • It acts like a substitute for dopamine in your brain.

  • Take tablets after food to help prevent feeling sick.

  • Swallow prolonged-release tablets whole; do not crush or break them.

  • Drowsiness, sudden sleep, and dizziness are common side-effects.

  • Tell your doctor if you experience changes in behaviour, such as increased gambling or sex drive.

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About ropinirole

Type de médicament

A dopamine-receptor agonist

Utilisé pour

Parkinson's disease; restless legs syndrome

Aussi appelé

For Parkinson's disease: Ippinia® XL; Ralnea® XL; Raponer® XL; Repinex® XL; Requip®; Requip® XL; Ropiqual® XL;
For restless legs syndrome
: Adartrel®

Disponible sous forme de

Tablets and prolonged-release tablets

Most brands of ropinirole tablets are prescribed to treat la maladie de Parkinson. Parkinson's disease affects the way your brain co-ordinates the movements of your muscles. A number of cells in a small part of your brain called the substantia nigra become damaged and die. These brain cells pass messages down nerves in the spinal cord by producing a chemical called dopamine, and it is these messages which control the muscles of the body. As the cells in the brain are damaged, the amount of dopamine that is produced is reduced. A combination of the reduction of cells and a low level of dopamine in the cells in this part of the brain, causes nerve messages to the muscles to become slowed and abnormal. This produces the main symptoms of Parkinson's disease, which are stiffness, shaking (tremor), and slowness of movement.

Ropinirole is a dopamine-receptor agonist which means that it acts on the same receptors in your brain as dopamine. In effect, it acts like a substitute for dopamine and this helps to ease your symptoms. It may be used alone, or in combination with other medicines to treat Parkinson's disease.

A brand of ropinirole called Adartrel® is used to treat syndrome des jambes sans repos (RLS). This is an uncomfortable feeling in your legs, which gives you the urge to move your legs to get relief. Ropinirole can help when these symptoms are severe enough to cause distress.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking ropinirole it is important that your doctor knows:

  • Si vous êtes enceinte, essayez d'avoir un bébé ou allaitez.

  • If you have a heart condition or a blood vessel disorder.

  • Si vous avez des problèmes avec le fonctionnement de votre foie, ou des problèmes avec le fonctionnement de vos reins.

  • If you have ever had a mental health problem such as psychosis.

  • Si vous prenez ou utilisez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et complémentaires.

  • Si vous avez déjà eu une réaction allergique à un médicament.

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  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack and any additional information your doctor has given to you. These will give you more information about ropinirole, and will also provide you with a full list of side-effects which you could experience from taking it.

  • The dose you are prescribed will be tailored to suit you. Your doctor will tell you how many tablets to take, and how often to take them. This information will also be printed on the label of the pack of tablets to remind you about what the doctor said to you. Read the directions from your doctor carefully so that you know what dose is right for you each day, and take the tablets exactly as you have been told.

  • If you are taking ropinirole for the first time, your doctor will give you a small dose to begin with, and then gradually increase this over the first few weeks. Slowly increasing your dose like this will help to reduce side-effects such as dizziness and low blood pressure, which can occur when you first start treatment.

  • It is best to take ropinirole tablets after a meal or a snack. This will help to prevent feelings of sickness which can sometimes occur.

  • If you have been given a prolonged-release tablet of ropinirole for Parkinson's disease (these have 'XL' after the brand name), you should swallow the tablet whole. You can take it with a drink of water to help you swallow, but do not crush or break the tablet before you swallow it. This is because the tablets have been specially made to release the medicine they contain slowly over the day.

  • If you are taking Adartrel® for restless legs syndrome, please take your doses just before you go to bed each evening.

  • Try to get into a habit of taking your doses at the same times of day each day, as this will help you to remember to take them regularly. If you forget to take a dose, take it as soon as you remember. Try to take the correct number of doses each day, but do not take two doses at the same time to make up for a missed dose.

  • There are several different strengths and brands of ropinirole tablet. Each time you collect a prescription, please check the box to make sure that you have been given the type of tablets you are expecting. Ask your pharmacist to check for you if you are unsure about anything.

  • Try to keep all your regular appointments with your doctor. This is so your doctor can check on your progress. Ropinirole could cause your blood pressure to fall (particularly in the early days of your treatment) and your doctor will want to check for this.

  • Keep taking the tablets until your doctor tells you otherwise. Stopping suddenly can cause problems and your doctor will want you to reduce your dose gradually if you need to stop treatment. Also, if for any reason you do not take your tablets for more than a day or so, you should let your doctor know about this, as your dose may need adjusting.

  • Sometimes people taking medicines like ropinirole can fall asleep suddenly during the day with little or no warning of being tired beforehand. Until you know how you react, take extra care if you drive or operate machinery. If you do find yourself falling asleep suddenly, you should see your doctor as soon as possible for advice, and avoid driving, or using tools and machines, in the meantime.

  • Treatment with medicines like ropinirole can sometimes cause problems with impulsive types of behaviour. If you notice any changes in your behaviour, such as an increased desire to gamble, binge eat, or spend excessively, or an increased sex drive, you must let your doctor know as soon as possible.

  • People with Parkinson's disease are likely to be advised to stay as active as possible and to exercise regularly as much as they are able. You may walk more slowly than before, but a daily walk is good exercise and may help to loosen up stiff muscles.

  • If you are a driver you should tell the DVLA and your insurance company if you have Parkinson's disease. Depending on the severity of symptoms and the medicines that you are taking, you may still be allowed to drive following a medical assessment.

  • Smoking can interfere with the way ropinirole works. If you either start smoking or give up smoking while you are taking ropinirole, your dose may need to be adjusted, so you should let your doctor know about this.

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Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the common ones associated with ropinirole. You will find a full list in the manufacturer's information leaflet supplied with the tablets. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common ropinirole side-effects (these affect more than 1 in 10 people)

Que puis-je faire si je ressens cela ?

Se sentir malade (nausée) ou être malade (vomissements)

Stick to simple or bland meals (avoid rich and spicy foods). Take your doses after food

Common ropinirole side-effects (these affect fewer than 1 in 10 people)

Que puis-je faire si je ressens cela ?

Feeling drowsy or sleepy, falling asleep suddenly during the day

If this happens, do not drive and do not use tools or machines. Speak with your doctor as soon as possible if you start falling asleep suddenly during the day

Feeling dizzy or faint, especially when you stand or sit up

Getting up and moving around more slowly may help. If you begin to feel dizzy, lie down so that you do not faint, then sit for a few moments before standing. This usually passes as your body gets used to the tablets, but in the meantime do not drive and do not use tools or machines

Swollen legs and ankles, feeling nervous or confused, indigestion, tummy (abdominal) pain, uncontrollable muscle movements, hearing or seeing things that aren't real (hallucinations)

Si l'un de ces éléments devient problématique, parlez-en à votre médecin

Autres

ropinirole

side-effects

Que puis-je faire si je ressens cela ?

Impulsive types of behaviour (such as an increased desire to gamble, binge eat, or an increased sex drive)

Informez votre médecin de cela dès que possible

Si vous ressentez d'autres symptômes que vous pensez être dus aux comprimés, veuillez consulter votre médecin ou votre pharmacien pour obtenir des conseils supplémentaires.

  • Gardez tous les médicaments hors de la portée et de la vue des enfants.

  • Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.

Informations importantes sur tous les médicaments

Never take more than the prescribed dose. If you suspect that you or someone else might have an overdose of this medicine, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.

Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.

If you are due to have any treatment like an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking.

Si vous achetez des médicaments, vérifiez toujours avec un pharmacien qu'ils sont sûrs à prendre avec vos autres médicaments.

Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.

If you have any questions about this medicine, please ask your pharmacist for advice.

Signaler les effets secondaires d'un médicament ou d'un vaccin

Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Yellow Card website.

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Questions fréquemment posées

Can ropinirole cure Parkinson's disease or restless legs syndrome?

Ropinirole helps to ease the symptoms of Parkinson's disease by acting like a substitute for dopamine in the brain. Similarly, for restless legs syndrome, it can help relieve uncomfortable feelings. However, the article does not state that it provides a cure for either condition.

Why is it important to tell my doctor about other medicines I'm currently taking, even if they're not prescription?

It's important for your doctor to know about all medicines you are taking, including those bought without a prescription, as well as herbal and complementary medicines. This is because some medicines may not be suitable to take with ropinirole and could interact with it, potentially causing problems or affecting how ropinirole works.

What should I do if I forget to take a dose of ropinirole?

If you forget to take a dose, you should take it as soon as you remember. Try to take the correct number of doses each day, but do not take two doses at the same time to make up for a missed dose.

Why do some ropinirole tablets have 'XL' after their brand name, and how should I take them?

The 'XL' after a brand name indicates a prolonged-release tablet. These tablets are specially designed to release the medicine slowly over the day. If you are given these, you should swallow the tablet whole with a drink of water and not crush or break it.

Can I stop taking ropinirole if my symptoms improve?

You should not stop taking ropinirole suddenly without speaking to your doctor. Stopping suddenly can cause problems. If treatment needs to be stopped, your doctor will advise you to reduce your dose gradually.

What if I experience side-effects that are not listed in the article?

The article lists some common side-effects, and notes that a full list will be in the manufacturer's information leaflet. If you experience any other symptoms that you think may be due to the tablets, you should speak with your doctor or pharmacist for further advice.

Why is it important to take ropinirole after a meal or snack?

Taking ropinirole tablets after a meal or a snack can help to prevent feelings of sickness (nausea), which can sometimes occur with this medication.

Lectures complémentaires et références

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About the authorView full bio

Author image

Michael Stewart, MRPharmS

Medicine Leaflet Review Manager – Contractor, Pharmacist

BPharm (Hons), MRPharmS

Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.

About the reviewer

Author image

Sid Dajani

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

Historique de l'article

Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.

  • Prochaine révision prévue : 26 nov. 2027
  • 26 nov. 2024 | Dernière version

    Dernière mise à jour par

    Michael Stewart, MRPharmS

    Revu par

    Sid Dajani
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