keratin 83
Dernière mise à jour 18 Aug 2020
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La KRT83 gene provides instructions for making the type II hair keratin K83 protein (K83). This protein belongs to a group of proteins known as keratins, which are tough, fibrous proteins that form the structural framework of cells that make up the hair, skin, and nails. Each keratin protein partners with another keratin protein to form molecules called intermediate filaments. These filaments assemble into strong networks that provide strength and resiliency to the tissues and protect them from being damaged by everyday physical stresses. The K83 protein is found in cells that make up the inner compartment of the hair shaft known as the cortex, and this protein helps give hair its strength and elasticity.
Normal function
La KRT83 gene provides instructions for making the type II hair keratin K83 protein (K83). This protein belongs to a group of proteins known as keratins, which are tough, fibrous proteins that form the structural framework of cells that make up the hair, skin, and nails. Each keratin protein partners with another keratin protein to form molecules called intermediate filaments. These filaments assemble into strong networks that provide strength and resiliency to the tissues and protect them from being damaged by everyday physical stresses. The K83 protein is found in cells that make up the inner compartment of the hair shaft known as the cortex, and this protein helps give hair its strength and elasticity.
Conditions referring to this gene or chromosome
Other names
hair keratin K2.10
hard keratin, type II, 3
Hb-3
HB3
hHb3
K83
keratin 83, type II
keratin, hair, basic, 3
keratin-83
KRT83_HUMAN
KRTHB3
type II hair keratin Hb3
type-II keratin Kb23
Related patient information and medicines
Patient information leaflet
Maladie de Bowen
Keratinocytes. These cells are in layers above the basal layer. They make a substance called keratin which is a hard waxy material. Keratinocytes are constantly dividing and a certain number are dying at any given time. The top (horny) layer of the epidermis is made of dead keratinocytes which contain keratin. The top of the skin is constantly.
Patient information leaflet
Types de cancer de la peau
This leaflet gives a general overview about skin cancer and the different skin cancer types - melanoma and non-melanoma. What is cancer. These cells are in layers above the basal layer. They make a substance called keratin which is a hard wax-like material. Keratinocytes are constantly dividing and a certain number are dying at any given time. The.
Patient information leaflet
Cors et callosités
Chemical treatment... These usually contain salicylic acid, which is also present in many wart-removal products. Salicylic acid is a keratolytic, which means it dissolves the protein (keratin) that makes up most of les deux the corn and the thick layer of dead skin which usually tops it. It is important to use these products as directed in the package.
Patient information leaflet
Cholestéatome
Cholesteatoma is the name given to a collection of skin cells that form a pearly-white greasy-looking lump deep in the ear, usually at the top of the area behind the eardrum. What is a cholesteatoma. A cholesteatoma is a non-cancerous abnormal growth of skin-like tissue in the middle ear. Cholesteatomas ... What does a cholesteatoma look like. In.
Patient information leaflet
Kystes épidermoïdes et pilaires
Epidermoid and pilar cysts are commonly referred to as 'sebaceous cysts' (pronounced 'seb-ay-shuss'). They are overgrowths of skin cells (called keratin) held together in a little capsule, or sac. This substance is soggy keratin. Keratin is made by skin cells and is the substance that hairs are made from and the substance that covers the top layer.
Patient information leaflet
Milia
In other people, they may take longer to clear. In persistent cases, treatment may be suggested. What are milia. A milium is a small, raised bump on the skin. It is a type of tiny skin cyst filled with a protein called keratin. Many are usually found together and so they are called milia (the plural of milium). What do milia look like. As can be.
Lectures complémentaires et références
- keratin 83; MedlinePlus, National Library of Medicine.
- Langbein L, Rogers MA, Winter H, Praetzel S, Schweizer J. The catalog of human hair keratins. II. Expression of the six type II members in the hair follicle and the combined catalog of human type I and II keratins. J Biol Chem. 2001 Sep 14;276(37):35123-32. doi: 10.1074/jbc.M103305200. Epub 2001 Jul 9.
- Rogers MA, Langbein L, Praetzel S, Moll I, Krieg T, Winter H, Schweizer J. Sequences and differential expression of three novel human type-II hair keratins. Differentiation. 1997 Feb;61(3):187-94. doi: 10.1046/j.1432-0436.1997.6130187.x.
- Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW. New consensus nomenclature for mammalian keratins. J Cell Biol. 2006 Jul 17;174(2):169-74. doi: 10.1083/jcb.200603161. Epub 2006 Jul 10.
- van Steensel MA, Steijlen PM, Bladergroen RS, Vermeer M, van Geel M. A missense mutation in the type II hair keratin hHb3 is associated with monilethrix. J Med Genet. 2005 Mar;42(3):e19. doi: 10.1136/jmg.2004.021030. No abstract available.
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