synaptic Ras GTPase activating protein 1
Dernière mise à jour 2 mai 2023
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La SYNGAP1 gene provides instructions for making a protein, called SynGAP, that plays an important role in nerve cells in the brain. SynGAP is found at the junctions between nerve cells (synapses) where cell-to-cell communication takes place. Connected nerve cells act as the "wiring" in the circuitry of the brain. Synapses are able to change and adapt over time, rewiring brain circuits, which is critical for learning and memory. SynGAP helps regulate synapse adaptations and promotes proper brain wiring. The protein's function is particularly important during a critical period of early brain development that affects future cognitive ability.
Normal function
La SYNGAP1 gene provides instructions for making a protein, called SynGAP, that plays an important role in nerve cells in the brain. SynGAP is found at the junctions between nerve cells (synapses) where cell-to-cell communication takes place. Connected nerve cells act as the "wiring" in the circuitry of the brain. Synapses are able to change and adapt over time, rewiring brain circuits, which is critical for learning and memory. SynGAP helps regulate synapse adaptations and promotes proper brain wiring. The protein's function is particularly important during a critical period of early brain development that affects future cognitive ability.
Conditions referring to this gene or chromosome
Other names
KIAA1938
MRD5
neuronal RasGAP
Ras GTPase-activating protein SynGAP
ras/Rap GTPase-activating protein SynGAP
RASA5
synaptic Ras GTPase activating protein 1 homolog
synaptic Ras GTPase activating protein, 135kDa
synaptic Ras GTPase-activating protein 1
SYNGAP
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Lectures complémentaires et références
- synaptic Ras GTPase activating protein 1; MedlinePlus, National Library of Medicine.
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