Can I take Co-codamol and Sukkarto together?
Drug interaction guide
Originally published 25 Jan 2026
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There is no direct interaction between co-codamol and Sukkarto. However, both medications can sometimes cause stomach-related side effects like nausea or constipation, which may be more noticeable when taken together. Additionally, if you have severe kidney or liver problems, your doctor may need to adjust the doses of both medicines.
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Why this happens
Co-codamol (a combination of paracetamol and codeine) and Sukkarto (metformin) are processed by the body through different pathways. Co-codamol works on pain receptors in the brain and spinal cord, while Sukkarto works on how the liver produces glucose and how cells respond to insulin. They do not interfere with each other's absorption or metabolism.
What you should do
It is generally safe to take these two medicines together. Ensure you follow the prescribed doses for both. Because co-codamol can cause constipation and Sukkarto can sometimes cause an upset stomach, drink plenty of water and monitor for any digestive discomfort. If you feel very unwell or experience severe stomach pain, contact your GP.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Clause de non-responsabilité
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historique de l'article
Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.
25 janvier 2026 | Publié à l'origine
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