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Comprimés de diloxanide

Clinical author's note Michael Stewart 19/03/2019: Diloxanide tablets were discontinued in the UK in June 2018. At the time of review there are no branded or generic products containing diloxanide available in the UK. Diloxanide may still be available in other countries. This medicine leaflet is based on medical information available in the UK at the time of writing and is left here for reference purposes. Please also refer to the manufacturer's information supplied with your medicine.

Diloxanide is used to treat an infection in your bowel.

Take one tablet every eight hours for 10 days.

If you have diarrhoea, drink plenty of fluids so that you don't become lacking in fluid in the body (dehydrated).

Even if you don't feel unwell, it is important that you complete the full course of tablets.


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About diloxanide

Type de médicament

An amoebicide

Utilisé pour

Amoebiasis (in adults and in children over 12 years of age)

Aussi appelé

Diloxanide furoate

Disponible sous forme de

Tablets (discontinued), oral liquid medicine (special order)

Diloxanide is used to treat an infection caused by a very small living organism (amoeba) called Entamoeba histolytica (often shortened to E. histolytica).

Infection with the amoeba can occur after drinking water contaminated by infected stools (faeces) or eating food prepared or washed using contaminated water. Most people with amoebiasis do not develop any symptoms, but in those who do, diarrhoea is the most common symptom. People most at risk of amoebiasis include travellers to areas where infection with the amoeba is common, such as countries with poor sanitation.

Treatment for amoebiasis includes medication such as diloxanide to kill the organism, and drinking plenty of fluids to prevent lack of fluid in the body (dehydration).

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking diloxanide it is important that your doctor knows:

  • Si vous êtes enceinte ou si vous allaitez.

  • Si vous prenez ou utilisez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, tels que les médicaments à base de plantes et les médecines complémentaires.

  • Si vous avez déjà eu une réaction allergique à un médicament.

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  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about diloxanide, and will also provide you with a full list of the side-effects which you could experience from taking it.

  • Take the tablets exactly as your doctor tells you to. It is usual to take one tablet three times a day for 10 days. Space your doses out evenly throughout the day - so ideally, take one tablet every eight hours. You can take the tablets either with or without food.

  • Even if you feel well, keep taking the tablets until the course is finished (unless your doctor tells you to stop). If you forget to take a dose, take it as soon as you remember. Try to take the correct number of doses each day but do not take two doses at the same time to make up for a missed dose.

  • It is very important when you have diarrhoea that you drink plenty of fluids to prevent you from becoming lacking in fluid in the body (dehydrated). Your doctor will advise you about how much and what type of fluids you should drink.

  • Wash your hands thoroughly after going to the toilet. This will help to prevent the spread of the infection to others. Ideally, use liquid soap in warm running water, but any soap is better than none. Dry your hands properly after washing, and don't share towels or flannels with other people.

  • Regularly clean the toilets that you use with disinfectant. Keep a cloth just for cleaning the toilet (or use a disposable one each time). Remember to wipe the flush handle, toilet seat, bathroom taps and door handles at least once a day with hot water and detergent.

  • Be careful to wash your hands before preparing, serving, or eating your food. Don't prepare or serve food for others.

  • You should stay off work, school, college, etc, while you have amoebiasis. Your doctor will advise you when it is suitable for you to return. Avoid contact with other people as far as possible during this time.

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Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with diloxanide. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Diloxanide side-effects

Que puis-je faire si je ressens cela ?

Feeling sick (nausea) or being sick (vomiting), loss of appetite, diarrhoea, tummy (abdominal) cramps, wind (flatulence)

Optez pour des aliments simples - évitez les repas riches ou épicés

Skin rash and itching, headache, dizziness

These are usually mild, but should they become troublesome, speak with your doctor

Si vous ressentez d'autres symptômes que vous pensez être dus aux comprimés, parlez-en à votre médecin ou à votre pharmacien pour obtenir des conseils supplémentaires.

  • Gardez tous les médicaments hors de la portée et de la vue des enfants.

  • Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.

Informations importantes sur tous les médicaments

Si vous subissez une opération ou un traitement dentaire, informez la personne qui effectue le traitement des médicaments que vous prenez.

Si vous achetez des médicaments, vérifiez avec un pharmacien qu'ils sont compatibles avec vos autres médicaments.

Ne prenez jamais plus que la dose prescrite. Si vous soupçonnez que vous ou quelqu'un d'autre avez pris une surdose de ce médicament, rendez-vous immédiatement au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.

Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.

Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.

Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.

MHRA - Signaler des réactions indésirables

Signalez les effets secondaires suspectés des médicaments, vaccins, cigarettes électroniques, incidents liés aux dispositifs médicaux, produits défectueux ou falsifiés (contrefaits) à l'Agence de Régulation des Médicaments et Produits de Santé pour garantir une utilisation sûre et efficace.

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Lectures complémentaires et références

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About the authorView full bio

Author image

Michael Stewart, MRPharmS

Medicine Leaflet Review Manager – Contractor, Pharmacist

BPharm (Hons), MRPharmS

Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.

About the reviewer

Author image

Sid Dajani

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

Historique de l'article

Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.

  • Prochaine révision prévue : 2 mars 2028
  • 2 mars 2025 | Dernière version

    Dernière mise à jour par

    Michael Stewart, MRPharmS

    Revu par

    Sid Dajani
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