Comprimés d'edoxaban

About edoxaban

Edoxaban works by preventing your blood from clotting as quickly or as effectively as normal. It does this by blocking a substance in your blood, called 'factor Xa', which is involved in the development of blood clots.

Sometimes, harmful blood clots can form in the blood vessels of your legs, lungs, brain or heart, and cause a blockage. This is more likely to happen if you have had surgery, or if you have a fast irregular heartbeat. For many years, a medicine called warfarin has been commonly used to treat blood clots like these and also to help protect against them. However, people who take warfarin need to have regular blood tests to measure how quickly their blood clots. This often means that the dose of warfarin can change quite frequently. Edoxaban works in a slightly different way to warfarin, so people who take edoxaban do not need to have regular blood tests.

Edoxaban is prescribed to treat blood clots causing deep vein thrombosis and pulmonary embolism. You may also be prescribed edoxaban to help protect against recurrent blood clots, or if you have a certain type of irregular fast heartbeat known as atrial fibrillation.

Before taking edoxaban

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking edoxaban it is important that your doctor knows:

• Si vous êtes enceinte ou si vous allaitez.

• Si vous avez des problèmes médicaux qui augmentent votre risque de saignement, ou si vous avez récemment subi une intervention chirurgicale.

• Si vous avez une hypertension artérielle (hypertension).

• Si vous avez des problèmes avec le fonctionnement de votre foie, ou avec le fonctionnement de vos reins.

• If you have a problem with the blood vessels in your eyes, known as vascular retinopathy.

• Si on vous a dit que vous avez une affection appelée syndrome des antiphospholipides.

• Si vous avez déjà eu une réaction allergique à un médicament.

• Si vous prenez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et les médecines complémentaires.

How to take edoxaban tablets

• Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about edoxaban and will provide you with a full list of the side-effects which you could experience from taking it.

• Take edoxaban exactly as your doctor tells you to. It is taken once daily. Your doctor or pharmacist will tell you which strength of tablet is right for you as there are several strengths of edoxaban available (15 mg, 30 mg, and 60 mg). This information will also be printed on the label of the pack to remind you.

• Try to take your tablet around the same time of day each day. This will help you to remember to take edoxaban regularly. Edoxaban can be taken either with or without food, but it should preferably be swallowed with a drink of water.

• If you have difficulty swallowing, you can crush a Lixiana® tablet and mix it with water or apple purée immediately before taking. Take care to swallow the entire mixture.

• Si vous oubliez de prendre une dose, prenez-la dès que vous vous en souvenez. Si vous ne vous en souvenez que le lendemain, laissez de côté la dose oubliée de la veille et prenez la dose prévue normalement. Ne prenez pas deux doses en même temps pour compenser une dose oubliée.

Tirer le meilleur parti de votre traitement

• Essayez de respecter vos rendez-vous réguliers avec votre médecin. Cela permet à votre médecin de suivre vos progrès.

• The length of the course of treatment will depend upon why you are taking the tablets, but it will either be for several months, or long-term.

• If you are due to have an operation or dental treatment, please tell the person carrying out the treatment that you are taking edoxaban.

• If you take any medicines that you have bought without a prescription, check with a pharmacist that they are suitable to take with edoxaban. This is because some medicines, such as some painkillers, can interfere with it.

Can edoxaban tablets cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with edoxaban. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.

Important: if you experience any unusual bleeding, or bleeding that continues for more than ten minutes, speak with your doctor straightaway or go to your local accident and emergency department.

Si vous ressentez d'autres symptômes que vous pensez être dus aux comprimés, parlez-en à votre médecin ou à votre pharmacien pour obtenir des conseils supplémentaires.

How to store edoxaban

• Gardez tous les médicaments hors de la portée et de la vue des enfants.

• Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.

Informations importantes sur tous les médicaments