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Comprimés d'éplérénone

Inspra

Take eplerenone tablets once a day.

Do not use salt substitutes while you are taking eplerenone.

Make sure your doctor knows about any other medicines you are taking alongside eplerenone.

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About eplerenone

Type de médicament

An aldosterone antagonist

Utilisé pour

Insuffisance cardiaque

Également appelé

Inspra®

Disponible en

Tablettes

Heart failure means that your heart is not functioning as well as it should. In a healthy heart, a set amount of blood enters the heart during each heartbeat and is pumped out again. If you have heart failure, your heart cannot cope with pumping the full amount of blood in each heartbeat.

If you have heart failure which affects the left ventricle of your heart (left-sided heart failure), it can cause you to be short of breath. It can also be associated with a cough. This is generally worse when you are active (for example, walking uphill) or when you are lying flat in bed.

Eplerenone is prescribed alongside other medicines to help prevent worsening of heart failure in people who have left-sided heart failure. It works by blocking the action of a substance in your body called aldosterone. High levels of aldosterone can cause changes that result in heart failure. By blocking aldosterone, eplerenone helps prevent heart failure from worsening.

Before taking eplerenone

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking eplerenone it is important that your doctor knows:

  • If you have any problems with the way your kidneys work, or if you have any problems with the way your liver works.

  • If you have been told you have high levels of potassium in your blood.

  • Si vous êtes enceinte, si vous essayez d'avoir un enfant ou si vous allaitez.

  • Si vous prenez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles sans ordonnance, ainsi que les médicaments à base de plantes et les médicaments complémentaires.

  • Si vous avez déjà eu une réaction allergique à un médicament.

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How to take eplerenone

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about eplerenone, and it will also provide you with a full list of the side-effects which you could experience from taking it.

  • Take eplerenone exactly as your doctor tells you to. You will be prescribed one tablet to take every day. There are two strengths of tablet - you will be prescribed the lower-strength (25 mg) tablet to begin with, but this will be increased to the 50 mg strength tablet within a few weeks.

  • Swallow the tablet whole with a drink of water. You can take eplerenone either with or without food.

  • Unless your doctor tells you otherwise, you can generally take eplerenone at a time of day you find easy to remember. It is best, however, to try to take the tablets at the same time of day each day, as this will help you to remember to take your doses regularly.

  • If you forget to take a dose, take one as soon as you remember, if this is during the same day as your dose was due. If you do not remember until the following day, leave out the forgotten dose from the previous day and take the dose that is due as normal. Do not take two doses at the same time to make up for a missed dose.

Tirer le meilleur parti de votre traitement

  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. The salt balance in your bloodstream may be upset by eplerenone and your doctor will want you to have a blood test from time to time to check the amount of potassium in your blood.

  • Try to avoid things with a high potassium content, such as 'salt substitutes'. This is so the level of potassium in your body does not become too high.

  • For most people with heart failure, regular exercise is advised. The healthier the heart, the better it will pump. The level of exercise recommended varies from person to person, so before you start to exercise, get the go-ahead from your doctor.

  • Your doctor may advise you to make some lifestyle changes, like losing weight if you are overweight, reducing the amount of alcohol you drink, and stopping smoking. Following this advice will help to improve the health of your heart.

  • If you buy any medicines 'over the counter', check with a pharmacist that they are suitable to take with your prescribed medicines. This is because some painkillers called non-steroidal anti-inflammatory drugs (NSAIDs) may not be recommended for you.

  • Si vous devez subir une opération ou un traitement dentaire, indiquez à la personne chargée du traitement les médicaments que vous prenez.

  • Treatment with eplerenone is usually long-term, so continue to take the tablets regularly until you are advised otherwise by your doctor.

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Can eplerenone cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the more common ones associated with eplerenone. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.

Communs

eplerenone side-effects (these affect fewer than 1 in 10 people)

Que puis-je faire si je suis confronté à cette situation ?

Sensation de vertige ou d'étourdissement

If you begin to feel dizzy, lie down so that you do not faint, then sit for a few moments before standing. Do not drive and do not use tools or machines while affected. If this continues, speak with your doctor

Maux de tête

Buvez beaucoup d'eau et demandez à votre pharmacien de vous recommander un analgésique adapté. Si les maux de tête persistent, consultez votre médecin

Sensation de malaise (nausée)

Stick to simple foods - avoid fatty or spicy meals. If this continues, speak with your doctor

Diarrhée

Buvez beaucoup d'eau pour remplacer les liquides perdus. Si cette situation persiste, consultez votre médecin

Constipation

Eat a well-balanced diet and drink several glasses of water each day

Cough, itchy skin rash, kidney problems, muscle spasms, sleeping problems, back pain

En cas de troubles, parlez-en à votre médecin

Changes to blood tests (such as high blood potassium and high blood cholesterol)

Votre médecin vérifiera les éléments suivants

Si vous ressentez d'autres symptômes qui pourraient être dus aux comprimés, demandez conseil à votre médecin ou à votre pharmacien.

How to store eplerenone

  • Conservez tous les médicaments hors de la portée et de la vue des enfants.

  • Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.

Informations importantes sur tous les médicaments

Informations importantes sur tous les médicaments

Ne dépassez jamais la dose prescrite. Si vous pensez que vous ou quelqu'un d'autre avez pris une dose excessive de ce médicament, rendez-vous au service des accidents et des urgences de votre hôpital local. Emportez la boîte avec vous, même si elle est vide.

Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.

Ne gardez pas les médicaments périmés ou dont vous ne voulez plus. Apportez-les à votre pharmacie locale qui les éliminera pour vous.

Si vous avez des questions sur ce médicament, demandez à votre pharmacien.

Signaler les effets secondaires d'un médicament ou d'un vaccin

Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne sur le site web de la carte jaune.

Autres lectures et références

Historique de l'article

Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.

  • Prochaine révision prévue : 23 février 2026
  • 24 Feb 2023 | Dernière version

    Dernière mise à jour par

    Michael Stewart, MRPharmS

    Examiné par des pairs

    Sid Dajani
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