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Comprimés de dronédarone

Multaq

Dronedarone is given to maintain a regular heart rhythm after cardioversion. Treatment with it will be started by a heart specialist.

The usual dose is one tablet twice daily. Take the tablets during breakfast and your evening meal.

Dronedarone can cause a number of side-effects which your doctor will discuss with you before you start treatment. If you develop any signs of liver damage or heart failure, you must let your doctor know straightaway.

En un coup d'œil

  • Dronedarone is a medicine for people with an irregular heart rhythm called atrial fibrillation (AF).

  • It helps maintain a regular heart rhythm after a treatment called cardioversion.

  • Take tablets twice daily with food, usually breakfast and the evening meal.

  • Do not drink grapefruit juice and tell your doctor or dentist about all medicines you are taking.

  • See your doctor for regular check-ups and blood tests while taking this medicine.

  • Speak to your doctor immediately if you notice signs of heart failure or liver damage.

About dronedarone

Type de médicament

An anti-arrhythmic medicine

Utilisé pour

Atrial fibrillation (irregular heartbeats)

Aussi appelé

Multaq®

Disponible sous forme de

Comprimés

Dronedarone is prescribed for people with an irregular heart rhythm called atrial fibrillation (AF). AF happens when the normal controlling timer in the heart (that causes it to beat regularly) is overridden. This causes parts of the heart to beat very rapidly, and other parts to beat haphazardly. A treatment called cardioversion is a way of converting the irregular rhythm back to a normal regular rhythm. Dronedarone is prescribed to maintain the regular heart rhythm after cardioversion. It will be prescribed by a specialist doctor.

Before taking dronedarone

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking dronedarone it is important that your doctor knows:

  • Si vous êtes enceinte, essayez d'avoir un bébé, ou allaitez.

  • Si vous avez des problèmes avec le fonctionnement de votre foie ou de vos reins.

  • If you have any other heart conditions.

  • If you have ever had an allergic reaction to a medicine. It is particularly important that you tell your doctor if you have taken a medicine called amiodarone and had problems with your breathing as a result. Also let your doctor know if you are taking anticoagulant medicines like apixaban or rivaroxaban.

  • Si vous prenez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et les médecines complémentaires.

How to take dronedarone tablets

  • Before you start this treatment, read the manufacturer's printed information leaflet from inside your pack. The manufacturer's leaflet will give you more information about dronedarone and a full list of side-effects which you may experience from taking it.

  • Take dronedarone exactly as your doctor tells you to. It is usually taken twice daily, the first dose in the morning during breakfast and the second dose during the evening meal. Swallow the tablets with a drink of water.

  • If you forget to take a dose, take it (with something to eat) as soon as you remember. If when you remember, it is nearly time for your next dose then leave out the missed dose and take your next dose when it is due. Do not take two doses together to make up for a forgotten dose.

Tirer le meilleur parti de votre traitement

  • Try to keep your regular appointments with your doctor. This is so your doctor can check your heart rhythm and monitor your progress. Your doctor will also want to do some blood tests while you are on dronedarone to check your liver function.

  • Do not drink grapefruit juice while you are on dronedarone. This is because a chemical in grapefruit juice increases the amount of dronedarone in your bloodstream and increases the risk of side-effects.

  • Treatment with dronedarone can be long-term. You should continue to take the tablets unless you are advised otherwise.

  • If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking dronedarone.

  • If you buy any medicines, always check with a pharmacist that they are suitable to take with dronedarone. This is because a number of medicines can interfere with dronedarone.

Can dronedarone tablets cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with dronedarone. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common dronedarone side-effects (these affect fewer than 1 in 10 people)


Que puis-je faire si je ressens cela ?

Feeling sick (nausea), indigestion, tummy (abdominal) pain

Eat simple meals - avoid rich or spicy food

Diarrhée

Buvez beaucoup d'eau pour remplacer les fluides perdus

Se sentir fatigué

Do not drive and do not use tools or machines until you feel more awake

Important: dronedarone is associated with a number of serious unwanted effects affecting the heart and liver. You must let your doctor know immédiatement si vous remarquez l'un des éléments suivants :

  • An increase in weight, trouble breathing or feeling short of breath, swollen feet or legs. These could be signs of heart failure.

  • Extreme tiredness, abdominal pain, high temperature, sickness, itchy skin, dark urine or yellowing of your skin or of the whites of your eyes (jaundice). These could be signs of damage to your liver.

Si vous ressentez d'autres symptômes que vous pensez être dus au médicament, parlez-en à votre médecin ou à votre pharmacien.

How to store dronedarone

  • Gardez tous les médicaments hors de la portée et de la vue des enfants.

  • Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.

Informations importantes sur tous les médicaments

Informations importantes sur tous les médicaments

Ne prenez jamais plus que la dose prescrite. Si vous soupçonnez que vous ou quelqu'un d'autre avez pris une surdose de ce médicament, rendez-vous au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.

Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.

Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.

Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.

Signaler les effets secondaires d'un médicament ou d'un vaccin

Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Site web de Yellow Card.

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Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.

Questions fréquemment posées

What is atrial fibrillation and how does cardioversion relate to it?

Atrial fibrillation (AF) is an irregular heart rhythm where the heart's natural timer is overridden, causing parts of the heart to beat very rapidly and haphazardly. Cardioversion is a medical procedure used to convert this irregular rhythm back to a normal, regular heart rhythm. Dronedarone is then prescribed to help maintain this regular rhythm after a successful cardioversion.

Are there any specific foods or drinks I should avoid while taking dronedarone?

Yes, you should not drink grapefruit juice while taking dronedarone. A chemical in grapefruit juice can increase the amount of dronedarone in your bloodstream, which may increase your risk of experiencing side-effects.

What should I do if I forget to take a dose of dronedarone?

If you miss a dose, take it with something to eat as soon as you remember. However, if it's almost time for your next scheduled dose, you should skip the missed dose and just take your next dose when it's due. Do not take two doses together to compensate for a forgotten one.

How long will I need to take dronedarone?

Treatment with dronedarone can be long-term. You should continue taking the tablets regularly unless your doctor or a healthcare professional advises you otherwise.

What information should I provide to my doctor before starting dronedarone?

Before starting dronedarone, it's important to inform your doctor if you are pregnant, trying to conceive, or breastfeeding. Also, tell them if you have any liver or kidney problems, other heart conditions, or if you've had an allergic reaction to any medicine, especially experiencing breathing problems with amiodarone. It's also crucial to mention all other medicines you are taking, including over-the-counter, herbal, and complementary medicines, and if you are taking any anticoagulant medicines like apixaban or rivaroxaban.

Lectures complémentaires et références

À propos de l'auteurVoir la biographie complète

Image de l'auteur

Michael Stewart, MRPharmS

Responsable de l'examen des notices de médicaments – Contractuel, Pharmacien

BPharm (Hons), MRPharmS

Michael est un pharmacien communautaire exerçant dans les Midlands et le South Yorkshire avec plus de 20 ans d'expérience dans le conseil sur les médicaments et les conditions médicales. Il possède une solide expérience en formation dans le domaine de la santé, ayant produit et dispensé des cours de formation pour les équipes de pharmacie et le personnel des établissements de soins résidentiels, y compris les infirmières. Il a également contribué aux comités consultatifs de pharmacie pour la gestion des affections de faible gravité dans la communauté.

À propos du critique

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Sid Dajani

Sultan Dajani a obtenu son diplôme à la London School of Pharmacy en 1994 et est devenu le plus jeune membre élu du conseil de la Royal Pharmaceutical Society depuis sa fondation en 1842.

Historique de l'article

Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.

  • Prochaine révision prévue : 18 sept. 2026
  • 19 sept. 2023 | Dernière version

    Dernière mise à jour par

    Michael Stewart, MRPharmS

    Revu par

    Sid Dajani
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