Erythromycine avec zinc
Revu par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSDernière mise à jour 9 Nov 2022
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Use erythromycin solution twice daily, in the morning and the evening.
Apply it to all of the affected area of skin, not just to individual spots.
You may need to use the solution for 10-12 weeks before you notice the full benefit.
En un coup d'œil
Erythromycin with zinc skin solution (Zineryt®) is an antibiotic treatment for acne.
It kills bacteria and reduces inflammation to help clear spots.
Apply a thin layer to affected skin twice a day after washing.
Treatment can take 10-12 weeks to show full benefits.
Common side effects include skin irritation, itching, redness, or dry skin.
About erythromycin (with zinc) skin solution
Type de médicament | Antibacterial |
Utilisé pour | Acne (spots) |
Aussi appelé | Zineryt® (erythromycin with zinc acetate) |
Disponible sous forme de | Topical skin solution |
Acné is the common cause of spots. Most people with acne are aged between 12 and 25 years, but some older and younger people are affected too. Small sebaceous glands lie just under your skin surface and make an oil (sebum) that keeps your skin supple and smooth. Tiny pores on your skin allow the sebum to come on to the surface of your skin. In acne, some of these pores become blocked, causing inflamed spots.
Antibiotics, like erythromycin, work by killing germs (bacteria) that can contribute to acne. They also reduce inflammation. Erythromycin usually works well to clear acne spots which are inflamed and any surrounding skin inflammation. Zineryt® skin solution also contains zinc acetate. This is thought to aid skin healing.
There are also other skin preparations available which contain erythromycin and are prescribed for acne. These gels/solutions combine erythromycin with a topical retinoid agent. See separate medicine leaflets called Gel d'isotrétinoïne pour l'acné et Trétinoïne pour l'acné for more information about these products.
Erythromycin is also taken by mouth as a tablet, capsule or liquid medicine to treat infections - see the separate medicine leaflet called Érythromycine pour plus d'informations à ce sujet.
Before using erythromycin (with zinc) skin solution
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start using erythromycin solution it is important that your doctor or pharmacist knows:
If you are pregnant or breastfeeding. (Although erythromycin is not known to be harmful to an unborn baby, you should let your doctor know if you think you are pregnant.)
If you have ever had an allergic reaction to a medicine or a skin preparation.
How to use erythromycin (with zinc) skin solution
Before you start this treatment, read the manufacturer's printed information leaflet from inside your pack. The leaflet will give you more information about erythromycin solution and how to use it.
Apply erythromycin solution exactly as your doctor tells you to. Wash and gently dry your skin, and then apply a thin layer of solution to the area where your spots occur. Use the solution twice a day, preferably in the morning and the evening. Wash your hands well after you have finished using it.
Do not use the solution on any areas of skin which are sunburnt or sore. Also, try to avoid getting it on the sensitive areas of your skin in or around your nostrils, your eyes and your mouth. If you have been using a preparation for your acne that has caused your skin to peel, allow your skin to recover for a few days before you start using the solution.
Zineryt® skin solution should be discarded eight weeks after being prepared by your pharmacist. There will be an expiry date written on the label to remind you.
Tirer le meilleur parti de votre traitement
Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. A full course of treatment may last for 3-6 months.
You may have to use erythromycin solution for 10-12 weeks before you notice the full benefit. If after this time you still do not think your skin has improved, discuss it with your doctor.
It is recommended that you use a mild soap and lukewarm water to wash with, as very hot or cold water may worsen acne. Do not wash more than you normally do. You cannot clean off blackheads. The black tip of a blackhead is actually a skin pigment and cannot be removed by cleaning or scrubbing.
You may use make-up and moisturisers, but wait until your face has dried completely after using the solution, before you apply them.
During your treatment your doctor may ask you to use another skin preparation for a short while from time to time. It is important you follow your doctor's advice, as it will help prevent your spots from becoming resistant to treatment.
You can use Zineryt® skin solution when you are pregnant or breastfeeding. If you are breastfeeding you should not use the solution on the chest area.
Can using erythromycin (with zinc) skin solution cause problems?
Along with their useful effects, all medicines can cause unwanted side-effects although not everyone experiences them. The table below lists some of the most common ones associated with Zineryt® skin solution. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve over the first few days of using a new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.
Effets secondaires courants | Que puis-je faire si je ressens cela ? |
Skin irritation or itching, redness, dry skin | Take care not to apply too much solution. It may also help to use a fragrance-free, water-based moisturising cream. Do not use ointments or oil-rich creams, as these may clog pores |
If you experience any other symptoms which you think may be due to this preparation, speak with your doctor or pharmacist.
How to store erythromycin (with zinc) skin solution
Gardez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.
Zineryt® solution should only be used for eight weeks after it has been made up by your pharmacy. Check the expiry date on the bottle and do not use it after this date.
Informations importantes sur tous les médicaments
Informations importantes sur tous les médicaments
This preparation is for external use only. If someone swallows some of it, contact your doctor or pharmacist for advice or go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.
Si vous achetez des médicaments, vérifiez avec un pharmacien qu'ils sont sans danger à prendre avec vos autres médicaments.
Si vous subissez une opération ou un traitement dentaire, informez la personne qui effectue le traitement des médicaments que vous prenez.
This preparation is for you. Never give it to other people, even if their condition appears to be the same as yours.
Ne gardez jamais de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.
Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Site web de Yellow Card.

Vous n'êtes pas sûr de mélanger des médicaments ?
Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.
Questions fréquemment posées
What is the role of zinc in Zineryt®?
Zineryt® skin solution contains zinc acetate in addition to erythromycin. The zinc acetate is included because it is thought to help with the healing of the skin.
Are there other types of erythromycin skin treatments for acne?
Yes, there are other skin preparations available that contain erythromycin for acne. Some of these combine erythromycin with a topical retinoid agent. These products are discussed in separate medicine leaflets.
Can I use make-up or moisturiser while treating my acne with erythromycin solution?
Yes, you can use make-up and moisturisers. However, you should wait until your face has completely dried after applying the erythromycin solution before putting them on.
How should I wash my skin when using this treatment for acne?
It is recommended to use a mild soap and lukewarm water for washing, as water that is very hot or very cold can potentially worsen acne. You should not wash more frequently than you normally do.
What should I do if I notice skin irritation, itching, or redness?
If you experience skin irritation or itching, redness, or dry skin, try taking care not to apply too much solution. Using a fragrance-free, water-based moisturising cream might also help. Avoid using ointments or oil-rich creams, as these can clog your pores. If these side-effects continue or become troublesome, you should speak with your doctor or pharmacist.
Lectures complémentaires et références
- Manufacturer's PIL, Zineryt® cutaneous solution; Neon Healthcare Ltd, Le Compendium électronique des Médicaments. Daté de février 2022.
- Médicaments Complets BNF 89e Édition; Association Médicale Britannique et Société Royale Pharmaceutique de Grande-Bretagne, Londres.
À propos de l'auteurVoir la biographie complète

Michael Stewart, MRPharmS
Responsable de l'examen des notices de médicaments – Contractuel, Pharmacien
BPharm (Hons), MRPharmS
Michael est un pharmacien communautaire exerçant dans les Midlands et le South Yorkshire avec plus de 20 ans d'expérience dans le conseil sur les médicaments et les conditions médicales. Il possède une solide expérience en formation dans le domaine de la santé, ayant produit et dispensé des cours de formation pour les équipes de pharmacie et le personnel des établissements de soins résidentiels, y compris les infirmières. Il a également contribué aux comités consultatifs de pharmacie pour la gestion des affections de faible gravité dans la communauté.
À propos du critique

Sid Dajani
Sultan Dajani a obtenu son diplôme à la London School of Pharmacy en 1994 et est devenu le plus jeune membre élu du conseil de la Royal Pharmaceutical Society depuis sa fondation en 1842.
Historique de l'article
Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.
Article également disponible en Anglais, Allemand, Espagnol, Français, Italien, Portugais, Hindi, Hébreu, Arabe, and Suédois.
Next review due: 8 May 2027
9 Nov 2022 | Dernière version

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