Glyburide pour le diabète

About glyburide

L'insuline est une hormone produite naturellement par l'organisme, dans le pancréas. Elle aide à contrôler les niveaux de sucre (glucose) dans le sang. Si votre corps ne produit pas suffisamment d'insuline ou s'il n'utilise pas efficacement l'insuline qu'il produit, il en résulte une maladie appelée diabète (diabète sucré).

People with diabetes need treatment to control the amount of sugar in their blood. This is because good control of blood sugar levels reduces the risk of complications later on. Some people can control the sugar in their blood by making changes to the food they eat but, for other people, medicines like glyburide are given alongside the changes in diet.

Glyburide (also know as glibenclamide) works by increasing the amount of insulin that your pancreas produces. This helps to reduce the amount of sugar in your blood.

Glyburide is also available in combination with another antidiabetic medicine called metformin. This combination reduces the number of tablets you need to take each day.

Before taking glyburide

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking glyburide it is important that your physician knows:

• Si vous êtes enceinte, si vous essayez d'avoir un enfant ou si vous allaitez.

• Si vous avez des problèmes de fonctionnement du foie ou des reins.

• Si l'on vous a dit que vous étiez atteint de porphyrie ou d'un déficit en glucose 6-phosphate déshydrogénase (G6PD). Il s'agit de maladies héréditaires rares.

• Si vous prenez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles sans ordonnance, ainsi que les médicaments à base de plantes et les médicaments complémentaires.

• Si vous avez déjà eu une réaction allergique à un médicament.

How to take glyburide tablets

• Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about glyburide tablets and will provide you with a full list of the side-effects which you may experience from taking them.

• Take glyburide exactly as your physician tells you to. The usual starting dose is 5 mg daily. It is prescribed as a single dose to be taken with, or immediately after, breakfast.

• Depending on your blood sugar (glucose) levels, your daily dose may need to be increased. Your physician will do this slowly, usually increasing by one 2.5 mg tablet each week. Your blood sugar levels will need to be tested regularly.

• If you need higher doses your physician may ask you to take glyburide twice each day. If this happens take each dose with a meal or snack and try to space your doses evenly.

• Different manufacturers' products may contain different amounts of glyburide and have different recommended doses. Each time you get a prescription make sure you receive the same strength of tablet as before. Ask the pharmacist for advice if you are unsure.

• Si vous oubliez de prendre une dose à l'heure habituelle, prenez-la au cours du repas suivant. Si vous ne vous en rendez compte que le lendemain, ne prenez pas la dose oubliée. Ne prenez pas deux doses le même jour pour compenser une dose oubliée.

Tirer le meilleur parti de votre traitement

• It is important that you keep your regular physician's and laboratory appointments. This is so that your progress can be monitored. You will need regular check-ups with an eye clinic and a foot clinic as well as with your physician and diabetes clinic.

• Your physician may recommend that you test for sugar (glucose) in your blood regularly to check that your diabetes is being controlled. Your physician will show you how to do this.

• If you have been given advice by your physician about changes to your diet, stopping smoking or taking regular exercise, it is important for you to follow the advice you have been given.

• Make sure you know what it feels like if your blood sugar drops too low. This is known as hypoglycemia, or a 'hypo'. The first signs of hypoglycemia are feeling shaky or anxious, sweating, looking pale, feeling hungry, having a feeling that your heart is pounding (palpitations), and feeling dizzy. If this happens, eat something containing sugar, such as dextrose tablets, sugary candy or a sugary soda (non-diet). Then follow this up with a snack such as a sandwich or a banana.

• Low blood sugar can occur if you miss a meal, if you exercise more than usual, if you are ill, or if you drink alcohol.

• Do not drink alcohol, as it can affect the control of your blood sugar. Ask your physician if you need further advice about this.

• Si vous êtes conducteur, vous devez être particulièrement vigilant, car votre capacité de concentration peut être affectée si votre diabète n'est pas bien contrôlé. Il peut vous être conseillé de vérifier votre taux de glycémie avant de voyager et d'emporter une collation lors des longs trajets.

• All US states have special licensing laws for drivers with medical conditions. You may be required to report your diabetes to local agencies. Ask your physician for advice about the laws in your state.

• If you get unusually thirsty, pass urine more frequently than normal, or feel very tired, you should let your physician know. These are signs that there is too much sugar in your blood and your treatment may need adjusting.

• Check with your physician before taking up any new physical exercise, as this will have an effect on your blood sugar levels and you may need to check your blood levels more regularly.

• Si vous devez subir une opération ou un traitement dentaire, vous devez informer la personne chargée du traitement que vous êtes diabétique et lui donner une liste des médicaments que vous prenez.

• Si vous achetez des médicaments, vérifiez toujours auprès d'un pharmacien qu'ils vous conviennent.

• Treatment for diabetes is usually lifelong. Continue to take the tablets unless you are advised otherwise by your physician.

Can glyburide cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with glyburide. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your physician or pharmacist if any of the following continue or become troublesome.

Si vous ressentez d'autres symptômes qui pourraient être dus à ce médicament, parlez-en à votre médecin ou à votre pharmacien.

How to store glyburide

• Conservez tous les médicaments hors de la portée et de la vue des enfants.

• Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.
  

Informations importantes sur tous les médicaments