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Macrogols pour la constipation ou le nettoyage intestinal

CosmoCol, Movicol, Laxido

Carefully follow the printed information given with the preparation.

Mix the contents of the sachet into water before taking.

Common side-effects include feeling sick (nausea) and tummy (abdominal) discomfort or pain.

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About macrogols

Type de médicament

Osmotic laxative and bowel cleansing solution

Utilisé pour

Constipation; to evacuate the bowel before investigation or surgery

Aussi appelé

For constipation: CosmoCol®; Movicol®; Laxido®; Molaxole®; Strigol®
For bowel cleansing
: Klean-Prep®, Moviprep®

Disponible sous forme de

Sachets of powder or oral liquid medicine

Macrogols belong to a group of medicines known as osmotic laxatives. They are substances which are used medically to relieve constipation or to clear the bowel before some clinical procedures. They are sometimes called polyethylene glycols. Macrogols are identified by a number which represents their molecular weight so, for example, the macrogol used to relieve constipation is called macrogol '3350'.

Constipation is a common problem which can be caused by a number of things. Not eating enough fibre or not drinking enough fluid can cause constipation. Some conditions (such as pregnancy) can cause constipation, as can a lack of exercise or movement (such as being ill in bed) and some medicines. Macrogols relieve constipation by drawing water into your bowel to soften your stools, making them easier to pass.

Bowel cleansing solutions also contain macrogol '3350' although they are not treatments for constipation. They are used to ensure that the bowel is free of solid contents before a bowel examination or surgical procedure.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start the treatment it is important that your doctor or pharmacist knows:

  • Si vous êtes enceinte ou si vous allaitez.

  • If you have any bowel problems other than constipation, such as Crohn's disease, ulcerative colitis or toxic megacolon.

  • Si vous avez une maladie cardiaque.

  • Si vous avez déjà eu une réaction allergique à un médicament.

  • If you use starch-based food-thickeners to help with difficulty swallowing.

  • Si vous prenez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et les médecines complémentaires.

  • If the treatment is intended for a child. This is because laxatives should only be given to children on the advice of a doctor or healthcare professional.

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Before starting the treatment, read the manufacturer's printed information leaflet from inside the pack. It will tell you how to prepare your dose and how long the solution can be kept for after preparation. Once mixed with water, the solution should be kept in the fridge. Do not use any solution remaining after the time recommended in the manufacturer's instructions.

If taking for constipation (brands CosmoCol®, Movicol®, Laxido®, Molaxole®)

  • Your doctor will tell you how many sachets to take for each dose. A daily dose can range from 1-2 sachets daily, up to a maximum of 8 sachets daily. Unless the directions say otherwise, stir the contents of each sachet into half a glass of water (100-125 ml) before taking.

If taking for bowel cleansing (brands Klean-Prep®, Moviprep®)

  • You will be given written instructions from the clinic that will tell you how many sachets to make up into a solution, and when you should start to drink it. It is important that you follow the directions carefully.

  • You will also be given written instructions about what food or drink you can, or cannot, have until after the procedure is completed. Typically, the advice is to not eat any solid food from about two hours before you start drinking the solution. Again, it is important that you carefully follow the directions you are given.

  • The treatment can interfere with the absorption of medicines taken at the same time. If you take medication regularly, please ask your doctor about when to take your other medicines.

If taking for constipation

  • A healthy diet containing fibre (wholegrain breads and cereals, bran, fruit and green leafy vegetables) with several glasses of water each day and daily exercise are important in maintaining healthy bowel function.

  • You can read more about how to prevent or treat constipation in the separate condition leaflets called Constipation (for adults) and Constipation in Children.

If taking for bowel cleansing

  • The preparation will start to work after an hour or two, so stay near to a toilet while you are taking the solution.

  • If you have any questions about the treatment, contact the hospital department where you are receiving the treatment for further advice.

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Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with macrogol '3350'. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Effets secondaires courants

macrogol '3350' side-effects


Que puis-je faire si je ressens cela ?

Tummy (abdominal) pain, wind (flatulence), feeling sick (nausea)

These effects do not usually last for long. Drinking the solution more slowly may help

Si vous ressentez d'autres symptômes que vous pensez être dus au médicament, parlez-en à votre médecin ou à votre pharmacien pour obtenir des conseils supplémentaires.

  • Gardez tous les médicaments hors de la portée et de la vue des enfants.

  • Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.

Informations importantes sur tous les médicaments

Ne prenez jamais plus que la dose prescrite. Si vous soupçonnez que vous ou quelqu'un d'autre avez pris une surdose de ce médicament, rendez-vous au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.

Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.

Si vous subissez une opération ou un traitement dentaire, informez la personne qui effectue le traitement des médicaments que vous prenez.

Si vous achetez des médicaments, vérifiez avec un pharmacien qu'ils sont compatibles avec vos autres médicaments.

Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.

Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.

Signaler les effets secondaires d'un médicament ou d'un vaccin

Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le site web Yellow Card.

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Lectures complémentaires et références

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Historique de l'article

Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.

  • Next review due: 4 Oct 2026
  • 5 Oct 2023 | Dernière version

    Dernière mise à jour par

    Michael Stewart, MRPharmS

    Revu par

    Sid Dajani
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