Acide méfénamique pour la douleur et l'inflammation

About mefenamic acid

Analgésiques anti-inflammatoires like mefenamic acid are also called non-steroidal anti-inflammatory drugs (NSAIDs), or sometimes just 'anti-inflammatories'. Mefenamic acid is used to treat painful conditions such as l'arthrite, pain associated with heavy menstrual bleeding, and pain after surgical operations.

Mefenamic acid works by blocking the effect of natural chemicals called cyclo-oxygenase (COX) enzymes. These enzymes help to make other chemicals in the body, called prostaglandins. Some prostaglandins are produced at sites of injury or damage, and cause pain and inflammation. By blocking the effect of COX enzymes, fewer prostaglandins are produced, which means pain and inflammation are eased.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking mefenamic acid, it is important that your doctor knows:

• Si vous avez déjà eu un ulcère de l'estomac ou duodénal, ou si vous souffrez d'une maladie inflammatoire de l'intestin telle que la maladie de Crohn ou la colite ulcéreuse.

• Si vous avez de l'asthme ou tout autre trouble allergique.

• Si vous êtes enceinte, essayez d'avoir un bébé, ou allaitez.

• Si vous avez des problèmes avec le fonctionnement de votre foie, ou si vous avez des problèmes avec le fonctionnement de vos reins.

• If you have a heart condition or a problem with your blood vessels or circulation.

• Si vous avez de l'hypertension.

• Si vous avez des problèmes de coagulation sanguine.

• Si vous avez de l'épilepsie.

• If you have high blood sugar or cholesterol levels.

• Si vous avez un trouble du tissu conjonctif tel que le lupus érythémateux systémique. C'est une affection inflammatoire également appelée lupus ou LES.

• Si vous avez un trouble sanguin héréditaire rare appelé porphyrie.

• If you are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as as herbal and complementary medicines.

• Si vous avez déjà eu une réaction allergique à un autre AINS (comme l'aspirine, l'ibuprofène, le diclofénac et l'indométacine), ou à tout autre médicament.

• Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about mefenamic acid, and it will also provide you with a full list of the side-effects which you could experience from taking it.

• Take mefenamic acid exactly as your doctor tells you to. The usual dose is 500 mg, which is taken as two 250 mg capsules, or one 500 mg tablet. You will be asked to take this dose three times a day. If you are taking it for period pain, your doctor will likely suggest that you take it for a few days each month, starting on your first day of bleeding.

• Take mefenamic acid with food. This will help to protect your stomach from side-effects such as indigestion.

• If you forget to take a dose, take it as soon as you remember unless your next dose is due. If your next dose is due, then take the dose which is due but leave out the forgotten one. Do not take two doses together to make up for a missed dose.

• Your doctor will try to prescribe you mefenamic acid for the shortest time possible to reduce the risk of side-effects. If you need to take it over a long period of time, your doctor may want to prescribe another medicine along with it to protect your stomach from irritation.

• Try to keep any regular appointments with your doctor. This is so your doctor can check on your progress. It is especially important if you are taking mefenamic acid for a long-term condition.

• If you have asthma, symptoms such as wheeze or breathlessness can be made worse by anti-inflammatories. If this happens to you, you should stop taking mefenamic acid and see your doctor as soon as possible.

• There is known to be a small increased risk of heart and blood vessel problems in people taking some anti-inflammatory painkillers long-term. Your doctor will explain this to you and will prescribe the lowest suitable dose for the shortest time in order to reduce the risk. Do not take more than the recommended dose.

• If you buy any medicines, check with a pharmacist that they are suitable for you to take. This is because you should not take mefenamic acid with any other anti-inflammatory painkiller, some of which are available in cold and flu remedies which can be bought 'over the counter'.

• Si vous subissez une opération ou un traitement dentaire, informez la personne qui effectue le traitement des médicaments que vous prenez.

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the more common ones associated with mefenamic acid. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.

Important: if you experience any of the following less common but possibly serious symptoms, stop taking mefenamic acid and contact your doctor for advice straightaway:

• Si vous avez des difficultés respiratoires telles que des sifflements ou un essoufflement.

• If you have any signs of an allergic reaction such as swelling around your mouth or face, or an itchy skin rash.

• If you pass blood or black stools, bring up (vomit) blood, or have severe stomach pains.

Si vous ressentez d'autres symptômes que vous pensez être dus au médicament, parlez-en à votre médecin ou à votre pharmacien pour obtenir des conseils supplémentaires.

• Gardez tous les médicaments hors de la portée et de la vue des enfants.

• Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.