Nizatidine pour réduire l'acidité gastrique
Revu par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSDernière mise à jour 17 May 2024
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Nizatidine reduces the amount of acid produced in your stomach.
Any side-effects are usually mild and do not last long.
En un coup d'œil
Nizatidine is a medicine that reduces acid production in the stomach.
It treats conditions like stomach ulcers, duodenal ulcers, and acid reflux.
Take capsules as prescribed by your doctor, with or without food.
Side-effects like tiredness, itching, or sweating are usually mild.
Discuss continuing or troublesome side-effects with your doctor.
Dans cet article:
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About nizatidine
Type de médicament | médicament antagoniste des récepteurs H2-receptor antagonist |
Utilisé pour | Treatment of conditions caused by too much acid being produced in the stomach |
Disponible sous forme de | Capsules |
Nizatidine belongs to a group of medicines that reduce the amount of acid produced by the cells in the lining of the stomach. They are called 'histamine H2-receptor antagonists', but are commonly also called Bloqueurs H2.
Nizatidine can be helpful in the treatment of conditions caused by too much acid being produced in the stomach. These conditions include stomach ulcers (gastric ulcers), ulcers of the upper part of the intestine (duodenal ulcers), and acid reflux or heartburn (gastro-oesophageal reflux disease). Nizatidine can also be prescribed to treat ulceration of the stomach which has been caused by anti-inflammatoires non stéroïdiens (AINS). Although nizatidine can be helpful in the treatment of these conditions, in practice other medicines are usually tried first.
Acid is produced naturally in your stomach to help to digest food. Excessive amounts of acid can irritate the lining of your stomach, causing inflammation, ulcers and other conditions. Nizatidine works by reducing the amount of acid produced by your stomach. This helps to relieve symptoms and assist the healing process where damage has already occurred.
Before taking nizatidine
To make sure this is the right treatment for you, before you start taking nizatidine it is important that your doctor or pharmacist knows:
Si vous êtes enceinte ou si vous allaitez.
If you have any of the following symptoms: difficulty swallowing, loss of blood, weight loss, or if you are being sick.
Si vous avez des problèmes avec le fonctionnement de votre foie ou de vos reins.
Si vous avez déjà eu une réaction allergique à un médicament.
Si vous prenez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et les médecines complémentaires.
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How to take nizatidine
Before you start this treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about nizatidine and will provide you with a full list of the side-effects which you may experience from taking it.
Take nizatidine exactly as your doctor tells you to. There are two different strengths of capsule available - 150 mg and 300 mg. You may be prescribed nizatidine to take twice a day, in the morning and evening, or just once a day in the evening. Your doctor will tell you what dose is right for you and the directions will be on the label of the pack to remind you about what was said to you.
You can take nizatidine before or after meals.
If you forget to take a dose at your usual time, you can take it when you remember (unless it is nearly time for your next dose, in which case leave out the missed dose). Do not take two doses together to make up for a forgotten dose.
Tirer le meilleur parti de votre traitement
A course of treatment can vary in length depending upon the reason why you are taking nizatidine. You could be asked to take it for a week or two, or for several months. Keep any appointments that you have booked with your doctor so that your progress can be checked.
Some people say that certain foods make their symptoms worse. Foods and drinks that have been suspected of this include peppermint, tomatoes, chocolate, spicy foods, hot drinks, coffee, and alcoholic drinks. If it seems that a food is aggravating your symptoms, try avoiding it for a while to see if your symptoms improve. Also, try avoiding eating large meals, as these can make your symptoms worse too.
If you are overweight, this puts extra pressure on your stomach and encourages the symptoms of acid reflux. Losing some weight and eating a healthy balanced diet may help you.
Smoking increases the amount of acid produced by the stomach and may make your symptoms worse. If you are a smoker, speak with your doctor or pharmacist about how to quit.
If you buy any medicines 'over the counter', always check with a pharmacist that they are safe to take alongside your other medicines.
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Can nizatidine cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the ones associated with nizatidine, although these are generally mild and do not last long. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Nizatidine side-effects | Que puis-je faire si je ressens cela ? |
Feeling tired, skin itching, sweating | Si l'un de ces éléments devient problématique, parlez-en à votre médecin |
If you experience any other symptoms which you think may be due to nizatidine, speak with your doctor or pharmacist for further advice.
How to store nizatidine
Gardez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.
Informations importantes sur tous les médicaments
Informations importantes sur tous les médicaments
Ne prenez jamais plus que la dose prescrite. Si vous soupçonnez que vous ou quelqu'un d'autre avez pris une surdose de ce médicament, rendez-vous au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Si vous subissez une opération ou un traitement dentaire, informez la personne qui effectue le traitement des médicaments que vous prenez.
Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.
Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Site web de Yellow Card.

Vous n'êtes pas sûr de mélanger des médicaments ?
Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.
Questions fréquemment posées
What is nizatidine used for?
Nizatidine is prescribed to reduce the amount of acid produced in the stomach. It treats conditions like stomach and duodenal ulcers, acid reflux (heartburn), and stomach ulceration caused by NSAIDs. While effective, other medications are often tried first for these conditions.
How does nizatidine work?
Nizatidine works by blocking histamine H2-receptors in the stomach lining. This action reduces the production of stomach acid, which helps to alleviate symptoms and aid the healing of any existing damage caused by excessive acid.
What should I do if I forget to take a dose of nizatidine?
If you miss a dose of nizatidine, take it as soon as you remember. However, if it's nearly time for your next scheduled dose, you should skip the missed dose entirely. Do not take two doses at once to compensate for a forgotten one.
Can I take nizatidine with food?
Yes, you can take nizatidine either before or after your meals. The effectiveness of the medicine is not dependent on whether it's taken with food.
Are there any lifestyle changes I can make to help my condition while taking nizatidine?
Yes, several lifestyle adjustments can complement your treatment. Avoiding foods that seem to worsen your symptoms (such as peppermint, spicy foods, or coffee), eating smaller meals, losing weight if you are overweight, and stopping smoking can all help to improve your symptoms.
How long will I need to take nizatidine?
The duration of your nizatidine treatment can vary significantly depending on the specific condition it's being used to treat. You might take it for a short period, such as a week or two, or for several months. Your doctor will determine the appropriate length of treatment for you.
Lectures complémentaires et références
- Manufacturer's PIL, Nizatidine 150 mg and 300 mg capsules; Mylan, The electronic Medicines Compendium. Dated May 2023.
- Médicaments Complets BNF 89e Édition; Association Médicale Britannique et Société Royale Pharmaceutique de Grande-Bretagne, Londres.
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À propos de l'auteurVoir la biographie complète

Michael Stewart, MRPharmS
Responsable de l'examen des notices de médicaments – Contractuel, Pharmacien
BPharm (Hons), MRPharmS
Michael est un pharmacien communautaire exerçant dans les Midlands et le South Yorkshire avec plus de 20 ans d'expérience dans le conseil sur les médicaments et les conditions médicales. Il possède une solide expérience en formation dans le domaine de la santé, ayant produit et dispensé des cours de formation pour les équipes de pharmacie et le personnel des établissements de soins résidentiels, y compris les infirmières. Il a également contribué aux comités consultatifs de pharmacie pour la gestion des affections de faible gravité dans la communauté.
À propos du critique

Sid Dajani
Sultan Dajani a obtenu son diplôme à la London School of Pharmacy en 1994 et est devenu le plus jeune membre élu du conseil de la Royal Pharmaceutical Society depuis sa fondation en 1842.
Historique de l'article
Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.
Prochaine révision prévue : 24 avr. 2027
17 May 2024 | Dernière version

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