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Olanzapine

Zalasta, Zyprexa

Olanzapine belongs to a group of medicines called antipsychotics. It is taken once daily.

Keep your regular appointments with your doctor. This is so your progress can be checked.

The most common side-effects include feeling sleepy or dizzy, and increased weight.

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About olanzapine

Type de médicament

Un médicament antipsychotique

Utilisé pour

Easing the symptoms of schizophrenia and mania; preventing high mood swings in bipolar disorder

Également appelé

Zalasta®; Zyprexa®

Disponible en

Tablets, and melt-in-the-mouth (orodispersible) tablets

Olanzapine belongs to a group of medicines called antipsychotics. It may have been prescribed for you to relieve the symptoms of schizophrenia, or alternatively, it may have been prescribed for the treatment and/or prevention of high mood swings (mania). In both of these conditions, olanzapine works on the balance of chemical substances in your brain.

Maintenance doses of olanzapine can also be given to people with schizophrenia by depot injection. There is a separate medicine leaflet providing more information about this, called Olanzapine long-acting injection.

Before taking olanzapine

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking olanzapine it is important that your doctor knows:

  • Si vous êtes enceinte ou si vous allaitez.

  • Si vous souffrez d'une maladie cardiaque ou d'une maladie des vaisseaux sanguins.

  • Si vous avez des problèmes de foie, de reins ou de prostate.

  • Si vous avez des problèmes respiratoires.

  • If you are very constipated or think you may have a blockage in your bowel.

  • If you have any of the following: epilepsy, diabetes (diabetes mellitus), depression, Parkinson's disease, raised pressure in your eye (glaucoma) or a condition which causes muscle weakness, called myasthenia gravis.

  • If you have ever had yellowing of your skin or of the whites of your eyes (jaundice).

  • If you have a blood or bone marrow disorder.

  • Si vous avez une tumeur de la glande surrénale (appelée phaeochromocytome).

  • Si vous avez eu une réaction allergique à un médicament.

  • Si vous prenez ou utilisez d'autres médicaments. Cela comprend tous les médicaments que vous prenez et qui sont disponibles sans ordonnance, ainsi que les médicaments à base de plantes et les médicaments complémentaires.

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How to take olanzapine

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about olanzapine and it will also provide you with a full list of the side-effects which you may experience from taking it.

  • Your dose will be adjusted to suit your condition, so take olanzapine tablets exactly as your doctor tells you to. It is usual to be prescribed one dose of olanzapine to take each day. Your dose will be printed on the label of your pack to remind you about what the doctor said to you.

  • You can take olanzapine tablets either before or after meals.

  • Try to get into the habit of taking your dose at the same time of day each day, as this will help you to remember to take it. If you do forget to take a dose, take it as soon as you remember. If you do not remember until the following day then skip the missed dose but remember to take the dose that is due on that day. Do not take two doses at the same time to make up for a forgotten dose.

  • If you have been given orodispersible tablets (e.g Zyprexa® Velotabs) - these are tablets which dissolve in your mouth - place the tablet on your tongue and allow it to dissolve. Alternatively, if you prefer, you can take the orodispersible tablet stirred into a small glassful of any of the following drinks: water, orange or apple juice, milk or coffee.

Tirer le meilleur parti de votre traitement

  • Your treatment will require careful monitoring to make sure that you get the best possible benefit from olanzapine. Keep your regular doctor's appointments so that your progress can be checked. You will need to have some tests from time to time.

  • Treatment with olanzapine is usually long-term unless you experience an adverse effect. Keep taking it unless your doctor tells you otherwise. Stopping olanzapine suddenly can cause problems, so your doctor may want you to reduce your dose gradually if this becomes necessary.

  • If you drink alcohol, ask your doctor for advice. Alcohol increases the risk of side-effects from olanzapine so it is best avoided.

  • If you have diabetes you may need to check your blood glucose more frequently, as olanzapine may affect the levels of sugar in your blood. Your doctor will advise you about this.

  • Some medicines similar to olanzapine can cause the skin to become more sensitive to sunlight than normal. It may be advisable to use a sunscreen in bright sunlight until you know how your skin reacts.

  • Smoking may affect the amount of olanzapine in your body. Let your doctor know if you either start or stop smoking while you are taking olanzapine.

  • A small number of people taking medicines for mood disorders can have thoughts about harming themselves or ending their lives, particularly when a new medicine is started. It is very important that you tell your doctor about this if it happens to you.

  • If you are due to have any medical or dental treatment, tell the person carrying out the treatment which medicines you are taking. This is important because olanzapine may interfere with any anaesthetic you receive.

  • If you buy or take any 'over-the-counter' medicines or herbal remedies, please check with a pharmacist that they are suitable for you to take with olanzapine.

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Can olanzapine cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with olanzapine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common olanzapine side-effects (these affect more than 1 in 10 people)

Que puis-je faire si je suis confronté à cette situation ?

Sentiment de somnolence ou de vertige

Ne pas conduire et ne pas utiliser d'outils ou de machines

Augmentation du poids

Eat a well-balanced diet. Speak with a pharmacist if your weight becomes troublesome

Modification de certains résultats d'analyses sanguines

Votre médecin surveillera les éléments suivants

Common olanzapine side-effects (these affect fewer than 1 in 10 people)

Que puis-je faire si je suis confronté à cette situation ?

Feeling restless or tired

Speak with your doctor about this. Do not drive and do not use tools or machines while affected

Constipation

Boire beaucoup d'eau et avoir une alimentation équilibrée

Bouche sèche

Essayez de mâcher du chewing-gum sans sucre ou de sucer des bonbons sans sucre.

Unusual or uncontrollable muscle movements

Parlez-en à votre médecin

Increased appetite, feeling hot, swollen hands or feet, skin rash, reduced interest in sex, erectile dysfunction, aches and pains

Discutez-en avec votre médecin si l'un d'entre eux devient gênant.

Important: if you experience symptoms such as muscle stiffness, a very high temperature (fever), feeling confused, a fast heartbeat and sweating, you should contact your doctor immediately. These can be signs of a rare but serious condition known as neuroleptic malignant syndrome.

Si vous ressentez d'autres symptômes que vous pensez être dus aux comprimés, veuillez consulter votre médecin ou votre pharmacien pour obtenir des conseils supplémentaires.

How to store olanzapine

  • Conservez tous les médicaments hors de la portée et de la vue des enfants.

  • Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.

Informations importantes sur tous les médicaments

Informations importantes sur tous les médicaments

Ne dépassez jamais la dose prescrite. Si vous pensez que vous ou quelqu'un d'autre avez pris une dose excessive de ce médicament, rendez-vous au service des accidents et des urgences de votre hôpital local. Emportez la boîte avec vous, même si elle est vide.

Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.

Ne gardez pas les médicaments périmés ou dont vous ne voulez plus. Apportez-les à votre pharmacie locale qui les éliminera pour vous.

Si vous avez des questions sur ce médicament, demandez à votre pharmacien.

Signaler les effets secondaires d'un médicament ou d'un vaccin

Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne sur le site web de la carte jaune.

Autres lectures et références

Historique de l'article

Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.

  • Prochaine révision prévue : 1er août 2027
  • 5 Aug 2024 | Dernière version

    Dernière mise à jour par

    Michael Stewart, MRPharmS

    Examiné par des pairs

    Sid Dajani
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