Injection à action prolongée de flupentixol
Depixol, Psytixol
Revu par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSDernière mise à jour 23 nov. 2022
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Flupentixol long-acting injection will be given to you by your clinic doctor or nurse every 2-4 weeks.
If you miss an appointment for an injection, make another appointment as soon as possible.
There are a number of side-effects which you could experience from the treatment. If you are concerned about any, you should discuss them with your doctor.
En un coup d'œil
Flupentixol long-acting injection is an antipsychotic medicine given for schizophrenia and similar mental health problems.
It is a 'depot' injection given every 2 to 4 weeks to maintain symptom control after initial tablet treatment.
The injection continuously releases the medicine into your body, so you don't have to remember daily tablets.
Before treatment, tell your doctor about any existing health conditions or other medicines you are taking.
Common side-effects include sleepiness, restlessness, dry mouth, and pain at the injection site.
Contact your doctor immediately if you get muscle stiffness, high temperature, confusion, or a fast heartbeat.
About flupentixol long-acting injection
Type de médicament | An antipsychotic injection |
Utilisé pour | Maintainance of symptoms in adults with schizophrenia and other similar mental health problems |
Aussi appelé | Flupentixol decanoate: Depixol®; Psytixol® |
Disponible sous forme de | Long-acting 'depot' injection |
Flupentixol belongs to a group of medicines called antipsychotics. You will have been prescribed it to maintain symptom control of la schizophrénie.
Schizophrenia is a mental health condition that causes disordered ideas, beliefs and experiences. Symptoms of schizophrenia include hearing, seeing, or sensing things that are not real, having mistaken beliefs, feeling unusually suspicious, and becoming withdrawn. Flupentixol is used to relieve the symptoms of schizophrenia and other similar mental health problems. It works on the balance of chemical substances in your brain.
Long-acting, or 'depot', injections are used once your symptoms have been eased by taking tablets. The injection slowly releases flupentixol into your body and is given every 2-4 weeks. The main advantage of a depot injection is that you do not have to remember to take tablets every day.
Before having flupentixol long-acting injection
Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start having flupentixol long-acting injections, it is important that your doctor knows:
Si vous êtes enceinte ou si vous allaitez.
Si vous avez une maladie cardiaque ou une maladie des vaisseaux sanguins.
Si vous avez des problèmes avec le fonctionnement de votre foie, ou si vous avez des problèmes avec le fonctionnement de vos reins.
If you have prostate problems.
Si vous avez des problèmes de respiration.
If you have any of the following: epilepsy, diabetes (diabetes mellitus), depression, Parkinson's disease, raised pressure in your eye (glaucoma), thyroid problems, or a condition which causes muscle weakness, called myasthenia gravis.
If you have ever had yellowing of your skin or the whites of your eyes (jaundice).
If you have a blood disorder, particularly if you have the rare inherited blood disorder called porphyria.
Si vous avez une tumeur sur votre glande surrénale (une affection appelée phéochromocytome).
Si vous avez eu une réaction allergique à un médicament.
Si vous prenez ou utilisez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et complémentaires.
How flupentixol long-acting injection is given
Before you start the treatment, ask to read the manufacturer's printed information leaflet from inside the pack. The leaflet will give you more information about flupentixol, and it will also provide you with a full list of the side-effects which you could experience.
Flupentixol long-acting injection will be given to you by a doctor or nurse. If you haven't received an injection like flupentixol before, a small dose is usually given as a test one week before you have a full dose. This is to see how well you tolerate the injection. The injection is given into a muscle in your bottom (buttocks) or upper leg.
You may be asked to continue taking your tablets for a short while after you have had your first injection. This is because it can take a few weeks before you feel the full effect from the injection.
Treatment with flupentixol is usually long-term so that your symptoms don't return.
Tirer le meilleur parti de votre traitement
Your treatment will require careful monitoring to make sure that you get the best possible benefit from flupentixol. Keep your regular doctor's appointments so that you get your injections on time, and your progress can be checked. If you miss an appointment for an injection, contact your doctor to arrange for another appointment as soon as possible.
Flupentixol could cause your skin to become more sensitive to sunlight than normal. Avoid strong sunlight and sunbeds, and use a sun cream with a high sun protection factor even on bright but cloudy days.
If you drink alcohol, ask your doctor for advice about drinking while you are on flupentixol. Alcohol can increase the chance that you experience side-effects and may not be recommended for you.
If you have diabetes you may need to check your blood sugar (glucose) more frequently, as flupentixol can affect the levels of sugar in your blood. Your doctor will advise you about this.
If you are having any dental treatment or an operation, tell the person carrying out the treatment that you have had a flupentixol injection. This is important because it may interfere with the anaesthetic you receive.
If you buy or take any 'over-the-counter' medicines, check with a pharmacist that they are suitable for you to take with flupentixol.
Can flupentixol long-acting injection cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the more common ones associated with flupentixol. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.
Very common flupentixol side-effects (these affect more than 1 in 10 people) | Que puis-je faire si je ressens cela ? |
Se sentir somnolent | Ne conduisez pas et n'utilisez pas d'outils ou de machines lorsque vous êtes affecté |
Feeling restless, movement problems | Parlez avec votre médecin |
Bouche sèche | Essayez de mâcher du chewing-gum sans sucre ou de sucer des bonbons sans sucre |
Commun flupentixol side-effects (these affect fewer than 1 in 10 people) | Que puis-je faire si je ressens cela ? |
Pain at the site of the injection | This should not last long. If the area becomes red, swollen or 'lumpy', let your doctor know |
Feeling dizzy or tired, blurred vision | Ne conduisez pas et n'utilisez pas d'outils ou de machines lorsque vous êtes affecté |
Maux de tête | Buvez beaucoup d'eau et demandez à votre pharmacien de vous recommander un analgésique approprié. Si les maux de tête persistent, consultez votre médecin |
Unusual or uncontrollable muscle movements, feeling shaky | Parlez-en avec votre médecin |
Increased appetite and weight, difficulty sleeping, feeling agitated or confused, mood changes (such as feeling depressed), reduced interest in sex, loss of concentration, feeling short of breath, producing more saliva than usual, fast heartbeats, stomach upset, feeling sweaty, muscle aches, and difficulty passing urine | Discutez-en avec votre médecin si l'un d'eux devient gênant |
Important: if you experience symptoms such as muscle stiffness, a very high temperature, feeling confused or sweaty, a fast heartbeat, and urinary incontinence, you should contact your doctor immediately. These can be signs of a rare but serious condition known as neuroleptic malignant syndrome.
Si vous ressentez d'autres symptômes que vous pensez être liés à l'injection, consultez votre médecin ou votre pharmacien pour obtenir des conseils supplémentaires.
How to store flupentixol long-acting injection
Gardez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.
Informations importantes sur tous les médicaments
Informations importantes sur tous les médicaments
If you suspect that you have had an overdose of this medicine, go to the accident and emergency department of your local hospital at once.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.
Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Site web de Yellow Card.

Vous n'êtes pas sûr de mélanger des médicaments ?
Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.
Questions fréquemment posées
What is the main benefit of choosing a long-acting injection like flupentixol over daily tablets for schizophrenia?
The primary advantage of a long-acting, or 'depot', injection such as flupentixol is that it removes the need to remember to take tablets every day. Once your symptoms have been stabilised with tablets, this injection slowly releases the medicine into your body and is typically given every 2-4 weeks.
How long will I continue to receive flupentixol long-acting injections?
Treatment with flupentixol is usually considered long-term. This continuous treatment helps to prevent the return of your symptoms, ensuring ongoing symptom control for schizophrenia and similar mental health problems.
What should I do if I have diabetes and am prescribed flupentixol?
If you have diabetes, flupentixol can affect your blood sugar levels. Your doctor will advise you, but you may need to check your blood sugar (glucose) more frequently while on this medication. Always follow your doctor's specific guidance.
Can flupentixol make me more sensitive to the sun?
Yes, flupentixol can make your skin more sensitive to sunlight than usual. It's advisable to avoid strong sunlight and sunbeds. When outdoors, even on bright but cloudy days, you should use a sun cream with a high sun protection factor.
Is it safe to drink alcohol while I am having flupentixol injections?
It's important to discuss alcohol consumption with your doctor if you drink. Alcohol can increase the likelihood of experiencing side-effects from flupentixol, and it may not be recommended for you while on this treatment.
Lectures complémentaires et références
- Manufacturer's PIL, Depixol® 20 mg/ml solution for injection; Lundbeck Limited, The electronic Medicines Compendium. Dated January 2021.
- Médicaments Complets BNF 89e Édition; Association Médicale Britannique et Société Royale Pharmaceutique de Grande-Bretagne, Londres.
À propos de l'auteurVoir la biographie complète

Michael Stewart, MRPharmS
Responsable de l'examen des notices de médicaments – Contractuel, Pharmacien
BPharm (Hons), MRPharmS
Michael est un pharmacien communautaire exerçant dans les Midlands et le South Yorkshire avec plus de 20 ans d'expérience dans le conseil sur les médicaments et les conditions médicales. Il possède une solide expérience en formation dans le domaine de la santé, ayant produit et dispensé des cours de formation pour les équipes de pharmacie et le personnel des établissements de soins résidentiels, y compris les infirmières. Il a également contribué aux comités consultatifs de pharmacie pour la gestion des affections de faible gravité dans la communauté.
À propos du critique

Sid Dajani
Sultan Dajani a obtenu son diplôme à la London School of Pharmacy en 1994 et est devenu le plus jeune membre élu du conseil de la Royal Pharmaceutical Society depuis sa fondation en 1842.
Historique de l'article
Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.
Article également disponible en Anglais, Allemand, Espagnol, Français, Italien, Portugais, Hindi, Hébreu, Arabe, and Suédois.
Next review due: 22 May 2027
23 nov. 2022 | Dernière version

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