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Primidone pour l'épilepsie

Enodama

You need to take primidone regularly to prevent seizures from occurring. It is usually taken twice daily.

It may cause you to feel drowsy.

Do not drink alcohol.

Do not suddenly stop taking it as this is likely to make your fits return.

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About primidone

Type de médicament

Anti-epileptic

Utilisé pour

Épilepsie

Aussi appelé

Enodama®, Liskantin®, Mysoline®

Disponible sous forme de

Comprimés, médicament liquide oral

If you have épilepsie, it means that you have had repeated fits (seizures). A seizure is a short episode of symptoms caused by a burst of abnormal electrical activity in your brain. Different parts of the brain control different parts and functions of your body. Therefore, the symptoms that occur during a seizure depend on where the abnormal burst of electrical activity occurs. Symptoms that may occur during a seizure can affect your muscles, sensations, behaviour, emotions, consciousness, or a combination of these.

Epilepsy cannot be 'cured', but the seizures can be prevented in most people by suitable anti-epileptic medication. Primidone helps prevent seizures from occurring.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking primidone it is important that your doctor or pharmacist knows:

  • Si vous êtes enceinte, essayez d'avoir un bébé ou allaitez.

  • Si vous avez des problèmes respiratoires.

  • If you have ever had problems with drug or alcohol dependence.

  • Si vous avez des problèmes de foie ou de reins.

  • If you have a rare inherited blood disorder known as porphyria.

  • Si vous prenez ou utilisez d'autres médicaments. Cela inclut tous les médicaments disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et les médecines complémentaires.

  • Si vous avez déjà eu une réaction allergique à un médicament.

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  • Before you start this treatment, read the manufacturer's printed information leaflet from inside the pack. The leaflet will give you more information about primidone and a full list of side-effects which you may experience from taking it.

  • Take primidone exactly as your doctor has told you. It is usually taken twice a day, although to begin with you will be prescribed a small dose to take at bedtime. This will then be increased gradually. Increasing your dose slowly allows your doctor to make sure that you have the dose that best suits you, but avoids any unwanted symptoms. Your dose will be on the label of your pack to remind you how to take the tablets. You need to take primidone regularly to prevent the fits (seizures) from occurring.

  • You can take the tablets before or after food. You may find it helps to swallow them with a drink of water.

  • If you forget to take a dose, take it as soon as you remember. If it is almost time to take your next dose, skip the missed dose and take your next dose when it is due. Do not take two doses together to make up for a forgotten dose.

  • Essayez de respecter vos rendez-vous réguliers avec votre médecin. Cela permet à votre médecin de suivre vos progrès.

  • When you first start a new treatment for epilepsy there may be a change in the number or type of fits (seizures) you experience. Your doctor will advise you about this.

  • Different brands of primidone may act in a slightly different way in your body. Because of this your pharmacist will always try to give you tablets from the same manufacturer as you have had before. So, each time you collect a prescription, check to make sure your supply looks the same and that the brand name is the same. If you are unsure, or if you have any questions about your prescription, please ask your pharmacist to check it for you.

  • People with epilepsy must stop driving at first. Your doctor will advise you about when it may be possible for you to resume driving again. This will usually be after a year free of seizures.

  • Do not stop taking this medicine unless your doctor tells you to do so. Stopping it suddenly can cause your seizures to return and your doctor will want you to reduce your dose gradually if this is necessary. Also, taking primidone over a time may lead to your body becoming dependent on it and this is another reason why your doctor will want to reduce your dose slowly.

  • Emotional stress or a lack of sleep could make you more likely to have a seizure. Keeping to a regular sleep pattern and using relaxation exercises can reduce this risk. Speak with your doctor or pharmacist for advice.

  • If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking primidone.

  • If you buy any medicines, check with a pharmacist that they are suitable for you to take alongside primidone.

  • If you are a woman using hormonal contraception ('the pill'), discuss this with your doctor as primidone interferes with the pill, reducing its contraceptive effect. Other methods of contraception will be more suitable for you. If you want to have a family, make sure you discuss this with your doctor well in advance of becoming pregnant. This is so that you can be given advice from a specialist before you become pregnant. If you become pregnant while you are taking primidone, you should tell your doctor straightaway.

  • You are advised not to drink alcohol while you are on primidone. Primidone will make you feel sleepy and drinking alcohol will increase this.

  • While you are taking these tablets, there is a small risk that you may develop mood changes or distressing feelings, and thoughts about suicide. If this happens, you must tell your doctor straightaway.

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En plus de leurs effets bénéfiques, la plupart des médicaments peuvent provoquer des effets secondaires indésirables, bien que tout le monde ne les ressente pas. Ceux-ci s'améliorent généralement à mesure que votre corps s'adapte au nouveau médicament, mais parlez à votre médecin ou à votre pharmacien si l'un des effets secondaires suivants persiste ou devient gênant.

Common primidone side-effects

Que puis-je faire si je ressens cela ?

Feeling unsteady or tired

Getting up or moving more slowly should help. If this continues, let your doctor know

Feeling sleepy, eyesight problems

Make sure your reactions are normal before you use tools or machines

Sensation de malaise (nausée)

Optez pour des aliments simples - évitez les repas riches ou épicés

Feeling short of breath, behavioural changes, mood changes (such as feeling irritable, confused, excited or depressed)

Si l'un de ces éléments devient problématique, parlez-en à votre médecin

Important: your doctor will have discussed with you the possibility of some less common but more serious side-effects. Let your doctor know straightaway if you experience any of the following:

  • A high temperature (fever) and swollen glands.

  • Une éruption cutanée sévère.

  • Yellowing of your skin or the whites of your eyes (jaundice).

Si vous ressentez d'autres symptômes que vous pensez être dus à ce médicament, parlez-en à votre médecin ou à votre pharmacien.

  • Gardez tous les médicaments hors de la portée et de la vue des enfants.

  • Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.

Informations importantes sur tous les médicaments

Ne prenez jamais plus que la dose prescrite. Si vous soupçonnez que vous ou quelqu'un d'autre avez pris une surdose de ce médicament, rendez-vous immédiatement au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.

Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.

Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.

Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.

Signaler les effets secondaires d'un médicament ou d'un vaccin

Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Yellow Card website.

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Lectures complémentaires et références

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Historique de l'article

Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.

  • Next review due: 5 Apr 2028
  • 5 Apr 2025 | Dernière version

    Dernière mise à jour par

    Michael Stewart, MRPharmS

    Revu par

    Sid Dajani
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