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Injection à action prolongée de Fluphénazine

discontinued

Note de l'auteur clinique Michael Stewart 05/12/2022: Modecate® injections were discontinued in the United Kingdom in November 2020. At the time of review there are no licensed injection products containing fluphenazine available in the UK. Fluphenazine injections may still be available in other countries or as special order products. This medicine leaflet is based on medical information available in the UK at the time of writing and is left here for reference purposes. Please also refer to the manufacturer's information supplied with your medicine.

Fluphenazine long-acting injection will be given to you by your clinic doctor or nurse every 2-5 weeks.

If you miss an appointment for an injection, make another appointment as soon as possible.

If you either start or stop smoking whilst you are being treated with fluphenazine, tell your doctor. Your dose may need to be adjusted.

En un coup d'œil

  • Fluphenazine long-acting injection is an antipsychotic medicine given for schizophrenia and similar mental health problems.

  • It is a 'depot' injection given into a muscle every 2–5 weeks to maintain symptom control.

  • Tell your doctor about existing health conditions or medicines before starting treatment.

  • Avoid strong sunlight and sunbeds, and use high-factor sun cream whilst on this injection.

  • Keep regular appointments for injections and monitoring.

  • Contact your doctor immediately if you experience muscle stiffness, high temperature, confusion, sweating, fast heartbeat, and urinary incontinence.

About fluphenazine long-acting injection

Type de médicament

An antipsychotic injection

Utilisé pour

Maintenance of symptom control in adults with schizophrenia and other similar mental health problems

Aussi appelé

Fluphenazine decanoate; Modecate® (discontinued)

Disponible sous forme de

Long-acting 'depot' injection

Fluphenazine belongs to a group of medicines called antipsychotics. You will have been prescribed it to maintain symptom control of la schizophrénie.

Schizophrenia is a mental health condition that causes disordered ideas, beliefs and experiences. Symptoms of schizophrenia include hearing, seeing, or sensing things that are not real, having mistaken beliefs, feeling unusually suspicious, and becoming withdrawn. Fluphenazine is used to relieve the symptoms of schizophrenia and other similar mental health problems. It works on the balance of chemical substances in your brain.

Long-acting, or 'depot', injections are used once your symptoms have been eased by taking tablets. The injection slowly releases fluphenazine into your body and is given every 2-5 weeks. The main advantage of a depot injection is that you do not have to remember to take tablets every day.

Before having fluphenazine long-acting injection

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start having fluphenazine injections, it is important that your doctor knows:

  • Si vous êtes enceinte ou si vous allaitez.

  • If you know you have a heart condition or blood vessel disease (such as any thickening of the arteries in your head).

  • Si vous avez des problèmes avec le fonctionnement de votre foie, ou si vous avez des problèmes avec le fonctionnement de vos reins.

  • If you have prostate problems.

  • Si vous avez un trouble sanguin.

  • Si vous avez des problèmes de respiration.

  • If you have any of the following: epilepsy, depression, Parkinson's disease, raised pressure in your eye (glaucoma), thyroid problems, or a condition which causes muscle weakness, called myasthenia gravis.

  • If you have ever had yellowing of your skin or the whites of your eyes (jaundice).

  • Si vous avez une tumeur sur votre glande surrénale (une affection appelée phéochromocytome).

  • Si vous avez eu une réaction allergique à un médicament.

  • Si vous prenez ou utilisez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et complémentaires.

How fluphenazine long-acting injection is given

  • Before you start this treatment, ask to read the manufacturer's printed information leaflet from inside the pack. The leaflet will give you more information about fluphenazine, and it will also provide you with a full list of the side-effects which you could experience.

  • Fluphenazine long-acting injection will be given to you by a doctor or nurse. If you haven't received an injection like fluphenazine before, a small dose is usually given as a test 4-7 days before you have a full dose. This is to see how well you tolerate the injection. The injection is given into a muscle in your bottom (buttocks).

  • You may be asked to continue taking your currently prescribed tablets for a short while after you have had your first injection. This is because it can take a few weeks before you feel the full effect from the injection.

  • Treatment with fluphenazine is usually long-term so that your symptoms don't return.

Tirer le meilleur parti de votre traitement

  • Your treatment will require careful monitoring to make sure that you get the best possible benefit from fluphenazine. Keep your regular doctor's appointments so that you get your injections on time, and your progress can be checked. If you miss an appointment for an injection, contact your doctor to arrange for another appointment as soon as possible.

  • Medicines similar to fluphenazine can cause people to become more sensitive to sunlight than normal. It is recommended that you avoid strong sunlight and sunbeds, and use a sun cream with a high sun protection factor even on bright but cloudy days.

  • If you drink alcohol, ask your doctor for advice about drinking while you are on fluphenazine. Alcohol can increase the chance that you experience side-effects and may not be advisable for you.

  • Smoking can interfere with the way your body handles fluphenazine. If you either start smoking or quit smoking whilst you are having fluphenazine, please make sure that you tell your doctor. It is probable that your dose will need to be adjusted.

  • If you have diabetes you may need to check your blood glucose more frequently, as fluphenazine can affect the levels of sugar in your blood. Your doctor will advise you about this.

  • If you are having any dental treatment or an operation, tell the person carrying out the treatment that you have had a fluphenazine injection. This is important because it may interfere with the anaesthetic or painkillers you receive.

  • If you buy or take any 'over-the-counter' medicines, check with a pharmacist that they are suitable for you to take with fluphenazine.

Can fluphenazine long-acting injection cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the ones associated with fluphenazine. The best place to find a full list of the side-effects which can be associated with your injection, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.

Fluphenazine side-effects

Que puis-je faire si je ressens cela ?

Pain at the site of the injection

This should not last long. If the area becomes red, swollen or 'lumpy', let your doctor know

Feeling sleepy or dizzy, blurred vision

Ne conduisez pas et n'utilisez pas d'outils ou de machines lorsque vous êtes affecté

Bouche sèche

Essayez de mâcher du chewing-gum sans sucre ou de sucer des bonbons sans sucre

Unusual or uncontrollable muscle movements, feeling shaky

Parlez-en avec votre médecin

Feeling restless, movement problems

Parlez avec votre médecin

Maux de tête

Buvez beaucoup d'eau et demandez à votre pharmacien de vous recommander un analgésique approprié. Si les maux de tête persistent, consultez votre médecin

Changes in weight, stuffy nose, difficulty sleeping, feeling agitated or confused, sexual problems, breast changes, menstrual problems, fast heartbeats, poor judgement or reduced mental ability, stomach upset, constipation, and difficulty passing urine

Discutez-en avec votre médecin si l'un d'eux devient gênant

Important: if you experience symptoms such as muscle stiffness, a very high temperature, feeling confused or sweaty, a fast heartbeat, and urinary incontinence, you should contact your doctor immediately. These can be signs of a rare but serious condition known as neuroleptic malignant syndrome.

Si vous ressentez d'autres symptômes que vous pensez être liés à l'injection, consultez votre médecin ou votre pharmacien pour obtenir des conseils supplémentaires.

How to store fluphenazine long-acting injection

  • Gardez tous les médicaments hors de la portée et de la vue des enfants.

  • Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.

Informations importantes sur tous les médicaments

Informations importantes sur tous les médicaments

If you suspect that you have had an overdose of this medicine, contact the accident and emergency department of your local hospital for advice.

Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.

Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.

Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.

Signaler les effets secondaires d'un médicament ou d'un vaccin

Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Site web de Yellow Card.

vérificateur de symptômes

Vous n'êtes pas sûr de mélanger des médicaments ?

Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.

Questions fréquemment posées

What is the difference between fluphenazine tablets and the long-acting injection?

Fluphenazine tablets are typically used to initially ease symptoms. Once symptoms are under control, the long-acting injection, also known as a 'depot' injection, is used for maintenance. The main advantage of the injection is that it slowly releases the medication into your body over 2-5 weeks, meaning you don't have to remember to take tablets every day.

Why is a test dose given before the full fluphenazine long-acting injection?

If you haven't received a fluphenazine injection before, a small test dose is usually administered 4-7 days prior to the full dose. This is done to assess how well your body tolerates the injection before you receive the complete treatment.

How long will I need to continue taking fluphenazine long-acting injections?

Treatment with fluphenazine is usually long-term. This is to help prevent your symptoms from returning, ensuring ongoing symptom control.

Can fluphenazine affect my blood sugar if I have diabetes?

Yes, fluphenazine can affect the levels of sugar in your blood. If you have diabetes, your doctor may advise you to check your blood glucose more frequently while on this medication.

Is it safe to get dental treatment or an operation while on fluphenazine injections?

If you are having any dental treatment or an operation, it is important to inform the person carrying out the treatment that you have had a fluphenazine injection. This is because it could potentially interact with any anaesthetics or painkillers you might receive.

Lectures complémentaires et références

À propos de l'auteurVoir la biographie complète

Image de l'auteur

Michael Stewart, MRPharmS

Responsable de l'examen des notices de médicaments – Contractuel, Pharmacien

BPharm (Hons), MRPharmS

Michael est un pharmacien communautaire exerçant dans les Midlands et le South Yorkshire avec plus de 20 ans d'expérience dans le conseil sur les médicaments et les conditions médicales. Il possède une solide expérience en formation dans le domaine de la santé, ayant produit et dispensé des cours de formation pour les équipes de pharmacie et le personnel des établissements de soins résidentiels, y compris les infirmières. Il a également contribué aux comités consultatifs de pharmacie pour la gestion des affections de faible gravité dans la communauté.

À propos du critique

Image de l'auteur

Sid Dajani

Sultan Dajani a obtenu son diplôme à la London School of Pharmacy en 1994 et est devenu le plus jeune membre élu du conseil de la Royal Pharmaceutical Society depuis sa fondation en 1842.

Historique de l'article

Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.

  • Next review due: 11 Jun 2027
  • 12 déc. 2022 | Dernière version

    Dernière mise à jour par

    Michael Stewart, MRPharmS

    Revu par

    Sid Dajani
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