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Comprimés de Rivaroxaban

Xarelto

Rivaroxaban is a type of anticoagulant used to prevent or treat harmful blood clots.

The most common side-effects are bleeding (such as nosebleeds) and feeling sick (nausea).

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About rivaroxaban

Type de médicament

An anticoagulant

Utilisé pour

Pour prévenir ou traiter les caillots sanguins nocifs

Aussi appelé (Royaume-Uni et États-Unis)

Xarelto®

Disponible sous forme de

Comprimés

Rivaroxaban works by preventing your blood from clotting as quickly or as effectively as normal. It does this by blocking a substance in your blood which is involved in the development of blood clots, called factor Xa.

Sometimes, harmful blood clots can form in the veins of your legs, lungs, brain or heart, and cause a blockage. This is more likely to happen if you are having certain types of surgery, or if you have a fast irregular heartbeat. For many years, a medicine called warfarine has been commonly used to treat blood clots like these and also to help protect against them. However, people who take warfarin need to have regular blood tests to measure how quickly their blood clots. This often means that the dose of warfarin can change quite frequently. Rivaroxaban works in a slightly different way to warfarin, so people who take rivaroxaban do not need to have regular blood tests.

Rivaroxaban is prescribed to treat blood clots causing thrombose veineuse profonde et embolie pulmonaire. You may also be prescribed rivaroxaban to help protect against blood clots if you are having hip or knee surgery, or if you have a certain type of irregular fast heartbeat known as fibrillation auriculaire.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking rivaroxaban it is important that your doctor knows:

  • Si vous êtes enceinte ou si vous allaitez.

  • If you have had any surgery recently (other than hip or knee surgery).

  • If you have an ulcer in your stomach or intestines, or if you have recently recovered from one.

  • If you have high blood pressure (hypertension).

  • If you have a prosthetic heart valve or you are due to have heart valve replacement surgery.

  • If you have any medical problems that may increase your risk of bleeding.

  • If you have a problem with the blood vessels in your eyes, known as vascular retinopathy.

  • Si vous avez des problèmes avec le fonctionnement de votre foie, ou avec le fonctionnement de vos reins.

  • If you have a long-term lung condition called bronchiectasis.

  • Si on vous a dit que vous avez une affection appelée syndrome des antiphospholipides.

  • Si vous prenez ou utilisez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et complémentaires.

  • Si vous avez déjà eu une réaction allergique à un médicament.

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  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about rivaroxaban and will provide you with a full list of the side-effects which you may experience from taking it.

  • Take rivaroxaban exactly as your doctor tells you to. It is usual to take one dose each day if it is to prevent a blood clot. If you are being treated because you have a blood clot, you will be asked to take two doses each day to begin with. Then, after three weeks, your dose will be reduced to one dose each day.

  • Your doctor or pharmacist will tell you which strength of tablet is right for you as there are several strengths of rivaroxaban available. This information will be printed on the label of the pack to remind you.

  • If the strength of the tablets you have been prescribed is 10 mg or lower, you can take these tablets either before or after meals. If you have been given the higher 15 mg or 20 mg strength tablets, you should take these with or just after a meal. This is because more of the dose is absorbed from these higher-strength tablets when there is food present in your stomach.

  • Try to take rivaroxaban at the same time(s) each day, as this will help you to remember to take it regularly. If you have difficulty swallowing tablets, you can crush the tablet and mix it with a little water or apple purée to help you.

  • If you forget to take a dose, take it as soon as you remember. If when you remember, it is nearly time for your next dose then take your next dose when it is due but leave out the missed dose. Do not take two doses together to make up for a forgotten dose.

  • Essayez de respecter tous les rendez-vous réguliers avec votre médecin. Cela permet à votre médecin de suivre vos progrès.

  • If you have had hip or knee surgery, you will be asked to continue taking rivaroxaban for a certain number of weeks. If you are taking it for other reasons, you will be asked to continue to take it over a longer period of time.

  • If you take any medicines that you have bought without a prescription, check with a pharmacist that they are suitable to take with rivaroxaban. This is because some medicines, such as some painkillers, may interfere with it.

  • Si vous subissez une opération ou un traitement dentaire, informez la personne qui effectue le traitement des médicaments que vous prenez.

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Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with rivaroxaban. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common rivaroxaban side-effects (these affect fewer than 1 in 10 people)

Que puis-je faire si je ressens cela ?

Bleeding (such as nosebleeds)

If the bleeding continues or becomes troublesome, let your doctor know

Feeling sick (nausea), indigestion, stomach upset

If you are not already doing so, try taking your doses after a meal

Feeling dizzy, tired or faint

If this happens, do not drive and do not use tools or machines until you feel well again

Changes in some blood tests, high temperature (fever), swollen feet or ankles, itchy rash

If you are concerned about any of these, speak with your doctor

Important: if you experience any unusual bleeding, speak with your doctor straightaway or go to your local accident and emergency department.

Si vous ressentez d'autres symptômes que vous pensez être dus aux comprimés, parlez-en à votre médecin ou à votre pharmacien pour obtenir des conseils supplémentaires.

  • Gardez tous les médicaments hors de la portée et de la vue des enfants.

  • Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.

Informations importantes sur tous les médicaments

Ne prenez jamais plus que la dose prescrite. Si vous soupçonnez que vous ou quelqu'un d'autre avez pris une surdose de ce médicament, rendez-vous au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.

Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.

Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.

Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.

MHRA - Signaler des réactions indésirables

Signalez les effets secondaires suspectés des médicaments, vaccins, cigarettes électroniques, incidents liés aux dispositifs médicaux, produits défectueux ou falsifiés (contrefaits) à l'Agence de Régulation des Médicaments et Produits de Santé pour garantir une utilisation sûre et efficace.

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Lectures complémentaires et références

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Historique de l'article

Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.

  • Next review due: 30 Nov 2026
  • 1 Dec 2023 | Dernière version

    Dernière mise à jour par

    Michael Stewart, MRPharmS

    Revu par

    Sid Dajani
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