Alfacalcidol en gélules et en gouttes
One-Alpha
Révision par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSDernière mise à jour le 23 août 2024
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Alfacalcidol is a type of vitamin D.
You will need to have regular blood tests while you are taking the medicine so that your doctor can adjust your dose.
Make sure you know the symptoms of too much calcium in your blood - these are losing your appetite, feeling thirsty, being sick (vomiting), feeling tired and losing weight. Please let your doctor know if you develop these symptoms.
Dans cet article :
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About alfacalcidol
Type de médicament | A type of vitamin D |
Utilisé pour | To promote healthy bones |
Également appelé | One-Alpha®; AlfaD®;AlciDol®; AlfacalEss®; |
Disponible en | Capsules, oral drops and injection |
Alfacalcidol is a type of vitamin D. Vitamin D helps to regulate the amount of calcium and phosphate in your body. All three of these substances are important for maintaining healthy, strong bones and teeth.
There are several types of vitamin D available but most other types need 'activating' by the kidneys. Alfacalcidol is a form of vitamin D which does not need this activation process, and so it is particularly helpful for people who need their bones strengthening but who also have kidney problems. You may also need to take mineral supplements along with alfacalcidol.
Alfacalcidol is available as capsules, as oral liquid drops and also as an injection.
Before taking alfacalcidol
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking alfacalcidol it is important that your doctor knows:
Si vous êtes enceinte ou si vous allaitez.
If you have ever had kidney stones or you have other problems with your kidneys.
If you know you have too much calcium in your blood or urine. This can happen with some cancers.
If you have any heart problems.
If you have an allergy to sesame oil (used in One-Alpha® capsules).
If you have been told you have sarcoidosis or other rare, 'granulomatous' disease.
Si vous prenez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles sans ordonnance, ainsi que les médicaments à base de plantes et les médicaments complémentaires.
Si vous avez déjà eu une réaction allergique à un médicament.
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How to take alfacalcidol
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about alfacalcidol and will provide you with a full list of the side-effects which you may experience from taking it.
Take alfacalcidol exactly as your doctor tells you to. It is usually taken as one dose a day. Try to take your doses at the same time of day each day, as this will help you to remember to take it regularly.
There are three strengths of capsule and one strength of oral drop available - your doctor will tell you what dose to take each day. Your dose could change from time to time depending upon the results of your routine blood tests.
Si vous oubliez de prendre une dose, prenez-la dès que vous vous en rendez compte. Si vous ne vous en rendez compte que le lendemain, ne prenez pas la dose oubliée. Ne prenez pas deux doses en même temps pour compenser une dose oubliée.
Directions for using One-Alpha® drops
Note: each drop contains 0.1 microgram (100 nanograms) of alfacalcidol.
Remove the bottle cap. (Do not shake the bottle before using.) You will see a dropper which is ready for you to use.
Hold the bottle upside down so that a drop appears at the end of the dropper. If a drop doesn't form, tap the bottle gently with a finger so that it does.
Let the drop fall into your (or your child's) mouth, or catch it on a spoon if this is easier. Your doctor will tell you how many drops to take - count these out carefully to make sure that you (or your child) take the correct number.
Tirer le meilleur parti de votre traitement
Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. Your doctor will want you to have regular blood tests during the treatment to check on the amount of calcium in your blood. Your dose of alfacalcidol will be adjusted as a result of having these tests.
Treatment with alfacalcidol may be for short periods of time (such as in preparation for surgery), or could be long-term. Please continue to take alfacalcidol regularly unless you are told otherwise by your doctor.
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Can alfacalcidol cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. Alfacalcidol occasionally causes skin rashes but other side-effects could be due to too much calcium being in your blood (see the table below). You will find a full list of side-effects in the manufacturer's information leaflet supplied with your medicine. Please speak with your doctor or pharmacist if any of the following continue or become troublesome.
Alfacalcidol side-effects | Que puis-je faire si je suis confronté à cette situation ? |
Skin rash and itchiness | En cas de troubles, parlez-en à votre médecin |
Sensation de vertige | Do not drive and do not use tools or machines until you are feeling better |
Loss of appetite, loss of weight, feeling tired, feeling sick (nausea), feeling thirsty, sweating, a metallic taste in your mouth, a need to pass urine more often | These are signs that there could be too much calcium in your blood. Make an appointment to see your doctor as soon as possible. Your dose may need adjusting or your treatment with alfacalcidol may need to be stopped for a few days |
If you experience any other symptoms which you think may be due to alfacalcidol, please speak with your doctor or pharmacist for further advice.
How to store alfacalcidol
Conservez tous les médicaments hors de la portée et de la vue des enfants.
Capsules should be stored in a cool, dry place, away from direct heat and light.
Oral drops should be kept refrigerated once the bottle has been opened. Do not use or keep an opened bottle for longer than 28 days.
Informations importantes sur tous les médicaments
Informations importantes sur tous les médicaments
Ne dépassez jamais la dose prescrite. Si vous pensez que vous ou quelqu'un d'autre avez pris une dose excessive de ce médicament, rendez-vous au service des accidents et des urgences de votre hôpital local. Emportez la boîte avec vous, même si elle est vide.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Si vous achetez des médicaments, vérifiez auprès d'un pharmacien qu'ils peuvent être pris avec vos autres médicaments.
Si vous devez subir une opération ou un traitement dentaire, indiquez à la personne chargée du traitement les médicaments que vous prenez.
Ne gardez pas les médicaments périmés ou dont vous ne voulez plus. Apportez-les à votre pharmacie locale qui les éliminera pour vous.
Si vous avez des questions sur ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne sur le site web de la carte jaune.
Autres lectures et références
- Manufacturer's PIL, One-Alpha® Capsules; Neon Healthcare Ltd, The electronic Medicines Compendium. Dated February 2022.
- Manufacturer's PIL, One-Alpha® oral drops; Neon Healthcare Ltd, The electronic Medicines Compendium. Dated February 2022.
- Médicaments Complet BNF 89ème éditionBritish Medical Association et Royal Pharmaceutical Society of Great Britain, Londres.
Historique de l'article
Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.
Prochaine révision prévue : 25 août 2027
23 Aug 2024 | Dernière version

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