Almotriptan pour la migraine
Revu par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSDernière mise à jour 5 Apr 2025
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Almotriptan is used to treat migraine headaches. Take one tablet as soon as you start to feel the head pain develop. Do not take it before the headache begins (for example, during the 'aura phase'), as it may be less effective.
Almotriptan can make you feel tired or sleepy. If this happens, do not drive and do not use tools or machines.
Your chest may feel tight or 'heavy' after taking almotriptan. These sensations do not usually last for long, but if they continue or become intense, do not take any more almotriptan tablets, and let your doctor know as soon as possible.
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About almotriptan
Type de médicament | A triptan (also known as a 5HT1-receptor agonist) |
Utilisé pour | Treatment of a migraine attack |
Disponible sous forme de | Comprimés |
Chez les personnes atteintes de migraine, it is thought that some chemicals in the brain increase in activity and as a result parts of the brain then send out confused signals which result in the symptoms of headache and sickness. Why people with migraine should develop these chemical changes is not clear, but for some people there may be things which trigger an attack, like certain foods or drinks.
Almotriptan belongs to a class of medicines known as 5HT1-receptor agonists. They are also known simply as triptans. Triptans work by stimulating the receptors of a natural substance in the brain called serotonin (also called 5HT). This eases the symptoms of a migraine attack.
Almotriptan is effective in relieving migraine attacks once an attack has started, but it does not help prevent headaches or migraine attacks from starting.
Before taking almotriptan
Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking almotriptan it is important that your doctor knows:
Si vous avez plus de 65 ans ou moins de 18 ans.
Si vous êtes enceinte ou si vous allaitez.
If you have a heart condition, angina, or if you have ever had a heart attack.
Si vous avez de l'hypertension.
If you have circulation problems caused by a condition called peripheral arterial disease.
If you have ever had a stroke or a transient ischaemic attack (also referred to as a TIA or a 'mini-stroke').
Si vous avez des problèmes avec le fonctionnement de votre foie, ou si vous avez des problèmes avec le fonctionnement de vos reins.
If you have ever had an allergic reaction to a medicine. It is particularly important that you tell your doctor if you have ever had a bad reaction to a sulfonamide medicine used to treat an infection.
Si vous prenez ou utilisez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et les médecines complémentaires.
How to take almotriptan
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about almotriptan, and will also provide you with a full list of the side-effects which you could experience from taking it.
Take almotriptan exactly as your doctor tells you to. Take one tablet as soon as the headache phase develops. If your migraine at first improves but then comes back, you may take a second tablet, providing it is at least deux heures after the initial dose. Do not take more than two tablets in 24 hours. If the first tablet has no effect, do not take a second dose for the same attack, as it is unlikely to work.
Swallow the tablet with a drink of water. You can take almotriptan whether or not you have recently eaten.
Tirer le meilleur parti de votre traitement
Almotriptan is used to treat headache pain during a migraine attack, not to stop the pain from coming on. You should wait until the headache (pain) is just beginning to develop, rather than taking it at the aura stage or when you feel that a migraine may be developing. Triptans probably work much less well if taken too early on in an attack.
Some people may benefit from taking a non-steroidal anti-inflammatory painkiller (such as naproxen) in addition to almotriptan. Your doctor will advise you about this if it is recommended for you. Do not take migraine treatments such as other triptans or ergotamine at the same time as almotriptan.
If you find that almotriptan does not relieve your migraine, make an appointment to discuss this with your doctor, as a different triptan medicine may be more effective for you.
Il peut être utile de tenir un journal des migraines. Notez quand et où chaque crise de migraine a commencé, ce que vous faisiez et ce que vous aviez mangé ce jour-là. Un schéma peut apparaître et il peut être possible pour vous d'éviter certaines des choses qui déclenchent vos crises de migraine.
Almotriptan is used to treat migraine attacks once the pain has started, but there are other medicines available that may help to reduce the number of migraine attacks. If you have migraines frequently, discuss this with your doctor.
Some people who get frequent migraine attacks are in fact getting medication-induced headache. Medication-induced headache (also called medication-overuse headache) is caused by taking painkillers or triptans too often. If you use almotriptan or painkillers on more than two days a week on a regular basis, you may be at risk of this. You should talk with your doctor if you suspect it.
Can almotriptan cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with almotriptan. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common almotriptan side-effects (these affect fewer than 1 in 10 people) | Que puis-je faire si je ressens cela ? |
Se sentir fatigué, somnolent ou étourdi | Si cela se produit, ne conduisez pas et n'utilisez pas d'outils ou de machines |
Se sentir malade (nausée) ou être malade (vomissements) | Stick to simple foods and drinks |
Important: after taking a triptan, some people can feel intense tightness or heaviness, particularly in the throat or chest. If this happens to you, do not take any further doses of this medicine and speak with your doctor about it as soon as possible.
Si vous ressentez d'autres symptômes que vous pensez être dus aux comprimés, consultez votre médecin ou votre pharmacien pour obtenir des conseils supplémentaires.
How to store almotriptan
Gardez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur directe et de la lumière.
Informations importantes sur tous les médicaments
Informations importantes sur tous les médicaments
Ne prenez jamais plus que la dose prescrite. Si vous soupçonnez que vous ou quelqu'un d'autre avez pris une surdose de ce médicament, rendez-vous immédiatement au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Si vous subissez une opération ou un traitement dentaire, informez la personne qui effectue le traitement des médicaments que vous prenez.
Ne conservez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.
Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Site web de Yellow Card.
Questions fréquemment posées
What is the appropriate timing for taking almotriptan during a migraine attack?
You should take almotriptan as soon as the headache phase starts. It is not recommended to take it during the 'aura' stage or when you only feel a migraine might be developing, as taking it too early may make it less effective.
Can almotriptan be used to prevent migraine attacks?
No, almotriptan is used for treating an existing migraine attack. It does not prevent headaches or migraine attacks from starting. If you experience frequent migraines, you should discuss other preventative medicines with your doctor.
What should I do if the first tablet of almotriptan doesn't help my migraine?
If the first tablet of almotriptan has no effect on your migraine, you should not take a second dose for the same attack, as it is unlikely to work. You should speak with your doctor if you find that almotriptan does not relieve your migraine attacks, as a different triptan medicine might be more effective for you.
Is it safe to use other painkillers with almotriptan?
Some people may benefit from taking a non-steroidal anti-inflammatory painkiller (such as naproxen) in addition to almotriptan, but your doctor will advise if this is recommended for you. You should not take other migraine treatments like other triptans or ergotamine at the same time as almotriptan to avoid potential risks.
What is medication-induced headache and how does it relate to almotriptan?
Medication-induced headache, also known as medication-overuse headache, can occur if you use painkillers or triptans like almotriptan too often. If you find yourself using almotriptan or painkillers more than two days a week on a regular basis, you might be at risk. It's important to discuss this with your doctor if you suspect you are experiencing it.
Lectures complémentaires et références
- Manufacturer's PIL, Almotriptan 12.5 mg Film-coated Tablets; Zentiva electronic Medicines Compendium. Dated November 2022.
- Médicaments Complets BNF 89e Édition; Association Médicale Britannique et Société Royale Pharmaceutique de Grande-Bretagne, Londres.
À propos du critique

Sid Dajani
Sultan Dajani a obtenu son diplôme à la London School of Pharmacy en 1994 et est devenu le plus jeune membre élu du conseil de la Royal Pharmaceutical Society depuis sa fondation en 1842.
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