Élétriptan pour la migraine
Relpax
Revu par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSLast updated 19 juin 2023
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Eletriptan is used to treat migraine headaches with or without aura.
Take one tablet as soon as you start to feel a migraine headache develop. Do not take it before the headache begins (for example, during the 'aura phase'), as it may be less effective.
Your chest may feel tight or 'heavy' after taking eletriptan. These sensations do not usually last for long, but if they continue or become intense, do not take any more tablets, and let your doctor know as soon as possible.
Eletriptan can make you feel sleepy. If this happens, do not drive and do not use tools or machines.
At a glance
Eletriptan (Relpax) is a medicine used to treat acute migraine attacks.
It works by stimulating serotonin receptors in the brain, easing migraine symptoms.
Take one tablet when a migraine headache starts; a second dose may be taken after two hours if needed.
Do not take more than two 40 mg tablets in 24 hours.
Discuss with your doctor if it doesn't relieve your migraine or if you have frequent attacks.
Common side-effects include tiredness, feeling sick, and 'cold-like' symptoms.
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About eletriptan
Type de médicament | 5HT1-receptor agonist (also known as a 'triptan') |
Utilisé pour | Treatment of acute migraine attacks |
Aussi appelé | Relpax® |
Disponible sous forme de | Comprimés |
It is not clear what causes migraine. It is thought that some chemicals in the brain increase in activity, and as a result parts of the brain then send out confused signals which result in the symptoms of migraine. Why people with migraine should develop these chemical changes is also not clear. Many migraine attacks occur for no apparent reason, but for some people there may be things which trigger an attack, like certain foods or drinks.
Eletriptan belongs to a class of medicines known as 5HT1-receptor agonists. They are also known simply as triptans. Triptans work by stimulating the receptors of a natural substance in the brain called serotonin (or 5HT). This eases the symptoms of migraine.
Eletriptan is effective in relieving migraine attacks once the headache phase has started. It does not help prevent migraine headaches from developing.
Before taking eletriptan
Retour au sommaireSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking eletriptan it is important that your doctor or pharmacist knows:
If you are aged over 65 years or under 18 years.
Si vous êtes enceinte ou si vous allaitez.
If you have heart problems such as an irregular heartbeat or angina, or if you have had a heart attack.
Si vous avez une hypertension artérielle (hypertension).
If you have circulation problems.
Si vous avez des problèmes avec le fonctionnement de votre foie ou de vos reins.
If you have ever had a stroke or a transient ischaemic attack (this is also referred to as a TIA, or 'mini-stroke').
Si vous avez déjà eu une réaction allergique à un médicament.
Si vous prenez ou utilisez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et complémentaires.
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How to take eletriptan
Retour au sommaireBefore you start this treatment, read the manufacturer's printed information leaflet from inside your pack. The manufacturer's leaflet will give you more information about eletriptan and a full list of the side-effects which you may experience from taking it.
Take eletriptan exactly as your doctor tells you to. It is usual to take one tablet as soon as you start to feel a migraine headache develop. Swallow the tablet with a drink of water.
If your migraine at first improves but then comes back again, you may take another tablet, providing it is at least two hours after you took the first one. If your migraine is not eased after taking the first tablet, a further dose is unlikely to work, so do not take a second tablet.
Do not take more than two 40 mg tablets in 24 hours.
Tirer le meilleur parti de votre traitement
Retour au sommaireEletriptan is meant to be used to treat headache pain during a migraine attack, not to stop the pain from coming on. You should wait until the pain is just beginning to develop, rather than taking it at the aura stage or when you feel that a migraine may be developing. Taking it earlier in a migraine attack will not stop the headache from developing.
You should not take other migraine treatments such as other triptans or ergotamine at the same time as eletriptan.
Some people may benefit from taking a non-steroidal anti-inflammatory painkiller (such as naproxen) in addition to eletriptan. Your doctor will advise you about this if it is recommended for you.
If you find that eletriptan does not relieve your migraine, make an appointment to discuss this with your doctor, as a different 'triptan' medicine may be more effective for you.
If you buy any 'over-the-counter' medicines, check with your pharmacist which medicines are safe for you to take.
It may help to keep a migraine diary. Note down when and where each migraine attack started, what you were doing, and what you had eaten that day. A pattern may emerge, and it may be possible to avoid one or more things that trigger your migraine attacks.
Eletriptan is used to treat migraine attacks, but there are other medicines that are available that may help to prevent you from having migraines. If you have migraines frequently, discuss this with your doctor.
Some people who get frequent migraine attacks are in fact getting medication-induced headache. Medication-induced headache (also called medication-overuse headache) is caused by taking painkillers or triptans too often. If you use eletriptan or painkillers on more than two days a week on a regular basis, you may be at risk of this. You should talk with your doctor if you suspect it.
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Can eletriptan cause problems?
Retour au sommaireAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with eletriptan. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common eletriptan side-effects (these affect fewer than 1 in 10 people) | Que puis-je faire si je ressens cela ? |
Feeling tired, dizzy or sleepy | Si cela se produit, ne conduisez pas et n'utilisez pas d'outils ou de machines |
Feeling sick (nausea), indigestion (reflux) | Optez pour des aliments simples |
'Cold-like' symptoms (such as chills, sore throat and runny nose), tingling feelings, feeling hot and flushed, the sensation of having a 'thumping heart' (palpitations), dry mouth | Si cela pose problème, parlez-en à votre médecin |
Some people feel tightness or pain in their throat or chest | If the pain is intense, do not take any further tablets and speak with your doctor about it |
If you experience any other symptoms which you think may be due to the tablets, speak with your doctor or pharmacist.
How to store eletriptan
Retour au sommaireGardez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.
Informations importantes sur tous les médicaments
Retour au sommaireInformations importantes sur tous les médicaments
Ne prenez jamais plus que la dose prescrite. Si vous soupçonnez que vous ou quelqu'un d'autre avez pris une surdose de ce médicament, rendez-vous au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Si vous subissez une opération ou un traitement dentaire, informez la personne qui effectue le traitement des médicaments que vous prenez.
Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.
Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Yellow Card website.

Vous n'êtes pas sûr de mélanger des médicaments ?
Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.
Questions fréquemment posées
Can eletriptan prevent my migraines from starting?
No, eletriptan is specifically designed to treat an acute migraine attack once the headache phase has already begun. It does not prevent migraines from developing. There are other medicines available for migraine prevention, which you can discuss with your doctor if you experience frequent attacks.
Is there a specific time during a migraine attack when I should take eletriptan for it to be most effective?
Yes, eletriptan is most effective when taken as soon as the migraine headache starts. It's not meant to be taken during the aura stage or when you just feel a migraine might be coming on, as taking it earlier won't prevent the headache from developing.
What should I do if the first tablet of eletriptan doesn't relieve my migraine?
If your migraine is not eased after taking the first tablet, it's unlikely that a second dose will work, so you should not take another tablet. You should discuss this with your doctor, as a different 'triptan' medicine might be more effective for you.
Can I take other pain relief medicines with eletriptan?
You should not take other migraine treatments like other triptans or ergotamine at the same time as eletriptan. However, some people may benefit from taking a non-steroidal anti-inflammatory painkiller, such as naproxen, in addition to eletriptan, if recommended by your doctor.
I get migraines very often. Could eletriptan itself be making them worse?
If you use eletriptan or painkillers on more than two days a week regularly, you might be at risk of developing medication-induced headache, also known as medication-overuse headache. This can happen if painkillers or triptans are used too often. If you suspect this, you should talk to your doctor.
What common side-effects should I be aware of when taking eletriptan?
Common side-effects include feeling tired, dizzy, or sleepy, feeling sick (nausea) or indigestion. You might also experience 'cold-like' symptoms such as chills, a sore throat, or a runny nose, tingling sensations, feeling hot and flushed, a 'thumping heart' sensation (palpitations), or a dry mouth. Some people also feel tightness or pain in their throat or chest. These effects often improve as your body adjusts.
What signs should I look out for that would mean I need to stop taking eletriptan immediately and contact a doctor?
If you experience intense pain or tightness in your throat or chest after taking eletriptan, you should not take any further tablets and speak with your doctor about it. You should always speak with your doctor or pharmacist if any side-effects become troublesome or if you experience any other symptoms you think might be due to the tablets.
Lectures complémentaires et références
- Manufacturer's PIL, Relpax® 20 mg and 40 mg Film-Coated Tablets; Upjohn UK Limited, The electronic Medicines Compendium. Dated June 2022.
- Médicaments Complets BNF 89e Édition; Association Médicale Britannique et Société Royale Pharmaceutique de Grande-Bretagne, Londres.
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About the authorView full bio

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Historique de l'article
Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.
Prochaine révision prévue : 18 juin 2026
19 juin 2023 | Dernière version

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