Omeprazole pour réduire l'acidité de l'estomac
Losec, Mezzopram, Prilosec
Révision par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSDernière mise à jour le 7 août 2023
Répond aux besoins du patient lignes directrices éditoriales
- TéléchargerTélécharger
- Partager
- Langue
- Discussion
Omeprazole reduces the amount of acid produced in the stomach.
Common side effects include stomach upset and headache. These effects are generally mild and do not last long.
Some omeprazole capsules and tablets should be swallowed whole; others can be mixed with water or fruit juice to make swallowing easier - check the manufacturer's printed information leaflet from inside the pack for directions.
Dans cet article :
Poursuivre la lecture ci-dessous
About omeprazole
Type de médicament | Proton pump inhibitor |
Utilisé pour | Healing or prevention of gastric or duodenal ulcers; gastro-oesophageal reflux disease; Helicobacter pylori infection; Zollinger-Ellison syndrome; acid-related dyspepsia; reduction of gastric acid during surgery |
Également appelé (UK) | Losec®; Mezzopram®; Pyrocalm Control® |
Appelé aussi (USA) | Prilosec® |
Disponible en | Capsules, tablets, dispersible tablets and injection |
What is omeprazole used for?
Omeprazole is a proton pump inhibitor (PPI) used to reduce the amount of acid in your stomach. It is usually prescribed for the treatment of digestive conditions such as acid reflux and stomach ulcers.
Omeprazole is also given as one part of a treatment to get rid of Helicobacter pylori, a bacterium found in the stomach, which can cause ulcers.
Omeprazole is available on prescription. You can also buy short courses of omeprazole at a pharmacy for the treatment of reflux symptoms (such as heartburn) in adults.
Poursuivre la lecture ci-dessous
How does omeprazole work?
Omeprazole works by stopping cells in the lining of the stomach from producing too much acid. This can help to prevent ulcers from forming, or assist the healing process where damage has already occurred.
By decreasing the amount of acid, they can also help to reduce the symptoms of acid reflux disease, such as heartburn.
Side effects of omeprazole
The most common side effects of omeprazole are:
Sensation de malaise (nausée).
Être malade (vomissements).
Maux d'estomac.
Farting.
Diarrhée.
Constipation.
Maux de tête.
Vous trouverez une liste complète dans la notice d'information du fabricant fournie avec votre médicament.
Les effets indésirables s'atténuent souvent au fur et à mesure que votre corps s'adapte au nouveau médicament, mais parlez-en à votre médecin ou à votre pharmacien si l'un des effets suivants persiste ou devient gênant.
Poursuivre la lecture ci-dessous
How to manage omeprazole side effects
Common omeprazole side effects (these affect fewer than 1 in 10 people) | Que puis-je faire si je suis confronté à cette situation ? |
Stomach upset, such as feeling sick, stomach ache, or wind (flatulence); tummy (abdominal) pain, being sick | Stick to simple meals - avoid rich or spicy foods. If symptoms are severe or do not go away, let your doctor know |
Diarrhée | Drink plenty of water. If it continues or becomes severe, let your doctor know |
Constipation | Essayez d'avoir une alimentation équilibrée et buvez plusieurs verres d'eau par jour. |
Maux de tête | Drink plenty of water and ask your pharmacist to recommend a suitable painkiller. If the headaches continue let your doctor know |
Si vous ressentez d'autres symptômes qui pourraient être dus au médicament, demandez conseil à votre médecin ou à votre pharmacien.
Who should not take omeprazole?
Some medicines are not suitable for people with certain conditions. Before taking omeprazole let your doctor know about any of the following:
Si vous êtes enceinte, si vous essayez d'avoir un enfant ou si vous allaitez.
Si vous présentez l'un des symptômes suivants : difficultés à avaler, perte de sang, perte de poids, ou si vous êtes malade (vomissements).
Si vous avez des problèmes de fonctionnement du foie.
Si vous avez déjà eu une réaction allergique à un médicament.
Si vous prenez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles sans ordonnance, ainsi que les médicaments à base de plantes et les médicaments complémentaires.
How to take omeprazole
Read the manufacturer's printed information leaflet from inside the pack. It will give you more information about omeprazole and will provide you with a full list of the side effects which you may experience from taking it.
Omeprazole tablets and capsules contain small pellets which are specially coated to make sure that the medicine is absorbed correctly by your body. Do not chew the pellets. If you find capsules or tablets difficult to swallow, let your doctor know.
Some omeprazole capsules and tablets can be mixed with water or fruit juice to make swallowing easier and your doctor can prescribe these for you.
Omeprazole can be taken before or after food, although taking it before food can be preferable.
Dosage
If you have bought omeprazole for reflux symptoms such as heartburn, take one or two (10 mg) tablets daily, preferably in a morning. You may need to take omeprazole for a day or so to control your symptoms. If your symptoms do not improve within this time, you should talk to your doctor about this.
Swallow the tablet with a drink of water - do not chew or crush the tablet before you swallow. Do not take omeprazole for more than four weeks without speaking with a doctor.
If you have been prescribed omeprazole, take it exactly as your doctor tells you to. There are different strengths of tablets and capsules available so your doctor will tell you which is right for you. It is usually taken once a day.
If you are taking it for either Helicobacter pylori eradication or for Zollinger-Ellison syndrome, it is likely you will be asked to take two doses a day. Your doctor will tell you which dose is right for you and the directions will also be on the label of the pack to remind you.
Missed dose
If you forget to take a dose at your usual time, you can take it when you remember (unless it is nearly time for your next dose, in which case leave out the missed dose).
Do not take two doses together to make up for a forgotten dose.
Tirer le meilleur parti de votre traitement
Try to keep your regular appointments with your doctor. This is so your progress can be checked. If you are taking omeprazole on a long-term basis your doctor will want to review your treatment at least once a year to make sure it is still right for you.
A typical course of treatment lasts for one or two weeks if you are taking omeprazole for Helicobacter pylori eradication. It will last for one or two months if it is to allow an ulcer to heal. For all other reasons for taking omeprazole, your treatment will last for as long as is necessary to control your symptoms.
Some foods may make your symptoms worse. Foods and drinks that have been suspected of this include peppermint, tomatoes, chocolate, spicy foods, hot drinks, coffee, and alcoholic drinks.
If it seems that a food is aggravating your symptoms, try avoiding it for a while to see if your symptoms improve.
Also, try avoiding eating large meals, as these can make your symptoms worse too.
Si vous êtes en surpoids, vous exercez une pression supplémentaire sur votre estomac et vous favorisez les symptômes du reflux acide. Perdre du poids et adopter un régime alimentaire sain et équilibré peut vous aider.
Le tabagisme augmente la quantité d'acide produite par l'estomac et peut aggraver vos symptômes. Si vous êtes fumeur, demandez à votre médecin ou à votre pharmacien comment arrêter de fumer.
Recent studies suggest that there may be a slight increase in the risk of bone fractures when proton pump inhibitors like omeprazole are taken for longer than a year. If this affects you, your doctor will check that you are taking enough vitamin D and calcium to reduce this risk.
Si vous achetez des médicaments en vente libre, vérifiez toujours auprès d'un pharmacien qu'ils peuvent être pris en même temps que vos autres médicaments.
How to store omeprazole
Conservez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.
Informations importantes sur tous les médicaments
Informations importantes sur tous les médicaments
Ne dépassez jamais la dose prescrite. Si vous pensez que vous ou quelqu'un d'autre avez pris une dose excessive de ce médicament, rendez-vous au service des accidents et des urgences de votre hôpital local. Emportez la boîte avec vous, même si elle est vide.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Si vous devez subir une opération ou un traitement dentaire, indiquez à la personne chargée du traitement les médicaments que vous prenez.
Ne gardez pas les médicaments périmés ou dont vous ne voulez plus. Apportez-les à votre pharmacie locale qui les éliminera pour vous.
Si vous avez des questions sur ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne sur le site web de la carte jaune.
Questions fréquemment posées
How long does omeprazole take to work?
Omeprazole usually starts to work within a few hours, but it can take 1 to 4 days to notice relief from heartburn, acid reflux, stomach ulcers, or GERD. How long it takes to fully work depends on what the condition is.
Is it safe to take omeprazole during pregnancy?
Omeprazole is generally considered safe to take during pregnancy for the treatment of heartburn or acid reflux. However, it’s best to speak with your doctor or midwife before taking it to make sure it’s the right option for you and to get the correct dose.
What should be avoided when taking omeprazole?
When taking omeprazole, avoid alcohol, smoking, and spicy, fatty, or acidic foods. You should also avoid taking omeprazole with certain medicines, such as antifungals, antivirals, or blood thinners, unless your doctor advises otherwise.
What happens if I suddenly stop taking omeprazole?
If you suddenly stop taking omeprazole, your stomach may produce more acid than before, causing your symptoms to return or worsen. This is known as acid rebound and can lead to heartburn, indigestion, or acid reflux. You should reduce your dose gradually to prevent symptoms from coming back.
Autres lectures et références
- Manufacturer's PIL, Losec® Capsules 10 mg, 20 mg and 40 mg; Neon Healthcare Ltd, The electronic Medicines Compendium. Dated March 2023.
- Manufacturer's PIL, Losec® MUPS Tablets 10 mg, 20 mg and 40 mg; Neon Healthcare Limited, The electronic Medicines Compendium. Dated March 2023.
Poursuivre la lecture ci-dessous
Historique de l'article
Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.
Prochaine révision prévue : 6 août 2026
7 Aug 2023 | Dernière version

Demandez, partagez, connectez-vous.
Parcourez les discussions, posez des questions et partagez vos expériences sur des centaines de sujets liés à la santé.

Vous ne vous sentez pas bien ?
Évaluez gratuitement vos symptômes en ligne
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.