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Butyrate de Clobétasone pour les affections inflammatoires de la peau

Clobavate, Eumovate

You only need to use a small amount of this preparation. Apply it thinly just to the areas affected, and then massage it gently into the skin until it disappears.

It must not be applied more than twice a day, and once a day is often sufficient.

Topical corticosteroids should not be used for long periods of time or on large areas of the body, especially in children. As a general guide, corticosteroids should not be used continuously for more than 5 days in children and 7 days in adults, unless your doctor gives specific instructions to do so.

En un coup d'œil

  • Clobetasone butyrate is a moderately potent topical steroid.

  • It treats inflammatory skin conditions like eczema and dermatitis by reducing inflammation, itching, and redness.

  • Apply a thin layer to affected areas usually once or twice a day.

  • Do not use on large skin areas or for long periods, especially in children.

  • If symptoms do not improve after 7-14 days, speak to your doctor.

Sélections vidéo pour Traitements des affections cutanées

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About clobetasone butyrate

Type de médicament

Un corticostéroïde topique d'intensité modérée

Utilisé pour

Conditions inflammatoires de la peau telles que l'eczéma et la dermatite

Aussi appelé

Clobavate®; Eumovate®;
Combination brands: Trimovate® (clobetasone with oxytetracycline and nystatin)

Disponible sous forme de

Crème et pommade

Clobetasone butyrate is classed as a moderately potent topical corticosteroid. Topical corticosteroids are also referred to as topical steroids. Topical steroids are used in addition to moisturisers (emollients) for treating inflammatory skin conditions such as eczéma et dermatite. A topical steroid is used when patches of eczema or dermatitis flare up. Clobetasone butyrate relieves the symptoms of a flare-up by reducing inflammation, itching and redness. It is not a cure for the condition, but it will help to relieve the symptoms. Although less potent topical steriods are often preferred for use in children, a short course of clobetasone butyrate may be prescribed for a child with severe eczema on the arms or legs.

Short courses of clobetasone butyrate may also be prescribed for the treatment of psoriasis for areas such as the face, or the inside of elbows and behind the knees.

It is likely you will be prescribed a cream if the affected areas of your skin are moist or weeping, or an ointment if your skin is dry. Clobetasone butyrate is available on prescription. Small packs of clobetasone butyrate can also be bought at a pharmacy, without a prescription, under certain conditions.

There is a brand of clobetasone butyrate called Trimovate®. This cream contains two antibacterial agents in addition to the topical steroid. These are oxytetracycline and nystatin. You may be prescribed this for a short period if some areas of your skin have become infected. It is typically used twice a day for one week only.

To make sure this is the right treatment for you, before you start using clobetasone butyrate it is important that your doctor or pharmacist knows:

  • Si vous avez des zones de peau infectée.

  • Si vous avez de la rosacée ou de l'acné.

  • Si vous êtes enceinte ou si vous allaitez.

  • Si vous avez déjà eu une réaction allergique à une préparation cutanée.

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  • Avant de commencer à utiliser la préparation, lisez la notice d'information imprimée fournie par le fabricant à l'intérieur du paquet. Elle vous donnera plus d'informations sur les stéroïdes topiques et vous fournira une liste complète des effets secondaires que vous pourriez ressentir lors de leur utilisation.

  • Apply a small amount to the areas of skin which are inflamed. Then gently rub it into the skin until it has disappeared. Unless you have been prescribed the brand called Trimovate®, do not use it on any areas of infected skin.

  • Your doctor will tell you how often to apply the cream or ointment. It should not be applied more than twice a day, and once a day is often sufficient.

  • La quantité de corticostéroïde topique que vous devez appliquer est généralement mesurée en unités fingertip (UF). Une UF correspond à la quantité de crème ou de pommade qui est pressée le long du bout du doigt d'un adulte (c'est-à-dire du bout du doigt jusqu'à la première pliure). En guise de guide, une UF suffit à couvrir une zone deux fois plus grande que la paume d'un adulte. Votre médecin vous indiquera combien d'UF vous devrez utiliser pour couvrir la zone de votre peau affectée.

  • Si vous utilisez plus d'un corticostéroïde topique, assurez-vous de connaître le moment et l'endroit où utiliser chacun d'eux. Si vous avez des doutes, consultez votre médecin ou demandez conseil à votre pharmacien.

  • After you have applied clobetasone butyrate, remember to wash your hands (unless your hands are the treated area).

  • If you are using clobetasone butyrate for psoriasis, make sure you follow your doctor's instructions carefully. It should not be used for large areas of psoriasis or for long periods of time, as these can cause your symptoms to flare up again afterwards.

  • Children are susceptible to side-effects from topical steroids. The main concern is for children who need frequent courses, as it can have an effect on their growth and this may need to be monitored. If your child has been prescribed clobetasone butyrate, follow the directions you have been given very carefully, and do not use it for longer than you have been told to. As a general rule, it should not be used for more than 1-2 weeks in children. It is not suitable for children under 12 years of age unless it has been prescribed by a doctor.

  • If you are using a moisturiser along with this preparation, apply the moisturiser first. Then wait 10-15 minutes before applying clobetasone butyrate. This allows time for the moisturiser to be absorbed before the topical corticosteroid is applied. Your skin should be moist but not slippery when you apply clobetasone butyrate.

  • If you have been told to use the cream/ointment on your face, be careful not to get any near your eyes and do not use it for longer periods of time than you have been advised.

  • Sauf avis contraire de votre médecin, n'appliquez pas de bandage ou de pansement sur la zone traitée, car cela augmenterait l'absorption du stéroïde à travers votre peau et le risque d'effets secondaires.

  • Your doctor will tell you how long to use the preparation for. The general rule is to continue to use the cream/ointment until the flare-up has gone and then to stop it. A course of treatment for 7-14 days is often sufficient. If your symptoms have not improved after this time (or if they get worse), speak again with your doctor for further advice. Some people with severe skin conditions may be advised to use it for up to four weeks between courses of more potent topical steroids. Clobetasone butyrate should not be used for long periods of time or on large areas of the body, especially in children.

  • If you are using Trimovate® cream, be careful not to let the preparation come into contact with your clothing, as it may stain.

  • After you finish using clobetasone butyrate, continue to use your moisturiser every day. This will help to prevent a further flare-up. Your doctor may also prescribe a less potent steroid cream for you to use when needed.

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Along with their useful effects, most medicines can cause unwanted side-effects but not everyone will experience them. Although side-effects from moderately potent corticosteroids like clobetasone butyrate are rare, you can reduce the risk further by applying the preparation thinly, no more than twice a day, and to the affected areas only.

Side-effects of clobetasone butyrate

Que puis-je faire si je ressens cela ?

Une sensation de brûlure ou de picotement

Ils peuvent apparaître dans les premiers jours, mais s'améliorent généralement par la suite

Thinning of the skin, permanent stretch marks, allergic contact dermatitis, acne, rosacea, and hair growth at the site of application

These would normally only affect you if you use clobetasone butyrate for long periods of time

Le stéroïde peut pénétrer votre peau et entrer dans votre circulation sanguine

This usually causes no problem unless you use clobetasone butyrate regularly for long periods of time on large areas of your skin

Important : there is a risk of fire when creams and ointments are absorbed by fabrics (such as clothing or bedsheets), making them flammable. A spark or flame can easily ignite the fabric. The risk is highest when large amounts of paraffin-based products are applied and absorb into fabrics. However, there is also a risk when non-paraffin products are used. Be aware of this fire hazard when repeatedly using large amounts of any skin product. Do not smoke or go near naked flames.

Lorsqu'il est utilisé conformément aux instructions de votre médecin ou de votre pharmacien, ce produit sera appliqué en petites quantités sur de petites zones de la peau. Il y aura une absorption minimale dans les tissus et un risque moindre d'incendie.

Important : continuous or prolonged use of corticosteroid skin preparations is not recommended. As a general guide, corticosteroids should not be used continuously for more than 5 days in children and 7 days in adults, unless your doctor gives specific instructions to do so. This is to prevent the risk of more serious side-effects with prolonged use. In addition, prolonged use can lead to more severe flare-ups of your skin condition when you do stop treatment. Always continue to moisturise your skin after stopping treatment with any corticosteroid preparation. If you experience severe redness, burning or stinging of your skin within a few days or weeks of stopping treatment you should consider over-use of the corticosteroid as a possible cause. Speak to your doctor or a pharmacist for advice in this case.

Si vous ressentez d'autres symptômes que vous pensez être liés à la crème ou à la pommade, consultez votre médecin ou votre pharmacien pour obtenir des conseils supplémentaires.

  • Gardez tous les médicaments hors de la portée et de la vue des enfants.

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Informations importantes sur tous les médicaments

Assurez-vous que la personne qui vous fournit ce médicament connaît tous les autres médicaments que vous prenez ou utilisez. Cela inclut les médicaments achetés, ainsi que les remèdes à base de plantes et homéopathiques.

Avant d'utiliser ce médicament, informez votre médecin si vous avez déjà eu une réaction allergique après avoir pris ou utilisé un médicament.

Ne jamais utiliser plus que la dose prescrite. Si vous pensez que quelqu'un a avalé accidentellement une partie du médicament, contactez le service des urgences de l'hôpital le plus proche pour obtenir des conseils.

Si vous subissez une opération ou un traitement dentaire, informez la personne qui réalise le traitement des médicaments que vous prenez ou utilisez.

Si vous achetez des médicaments, vérifiez avec un pharmacien qu'ils sont sans danger à prendre avec vos autres médicaments.

Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.

Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.

Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.

Signaler les effets secondaires d'un médicament ou d'un vaccin

Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Site web de Yellow Card.

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Questions fréquemment posées

Can I use clobetasone butyrate for all types of skin inflammation?

Clobetasone butyrate is used for inflammatory skin conditions like eczema and dermatitis, and for certain areas of psoriasis. However, it should not be used on infected skin unless specifically prescribed as the Trimovate® brand, which contains additional antibacterial agents. Always ensure your doctor or pharmacist knows if you have any infected skin, rosacea, or acne before you start treatment.

How do I know whether to use the cream or ointment form of clobetasone butyrate?

Your doctor will likely prescribe the cream if the affected areas of your skin are moist or weeping. If your skin is dry, an ointment formulation is usually preferred. The type prescribed is tailored to the specific condition of your skin.

I'm pregnant and have eczema. Can I use clobetasone butyrate?

If you are pregnant or breastfeeding, it is important to inform your doctor or pharmacist. They will advise you on whether clobetasone butyrate is suitable for you during this time.

What is a 'fingertip unit' and how do I measure it?

A fingertip unit (FTU) is a way to measure the amount of cream or ointment to apply. One FTU is the amount of preparation squeezed out along an adult's fingertip, from the very end of the finger to the first crease. This amount is typically enough to cover an area twice the size of an adult hand. Your doctor will provide guidance on how many FTUs you need for your specific affected area.

I have been using clobetasone butyrate for a while, and my skin seems to be getting worse after I stop. What should I do?

Continuous or prolonged use of corticosteroid skin preparations is not recommended, as it can lead to more severe flare-ups of your skin condition when treatment stops. This is known as rebound flare-up. If you experience severe redness, burning, or stinging of your skin within a few days or weeks of stopping treatment, you should speak to your doctor or pharmacist for advice.

How long can I typically use clobetasone butyrate?

The general rule is to use the cream or ointment until the flare-up has cleared, and then stop. A course often lasts 7-14 days. For children, it should generally not be used for more than 1-2 weeks. Some specific severe skin conditions might allow for use up to four weeks between courses of more potent steroids, but this will be under strict doctor's guidance. It should not be used for long periods of time or on large areas, especially in children.

Lectures complémentaires et références

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À propos de l'auteurVoir la biographie complète

Image de l'auteur

Michael Stewart, MRPharmS

Responsable de l'examen des notices de médicaments – Contractuel, Pharmacien

BPharm (Hons), MRPharmS

Michael est un pharmacien communautaire exerçant dans les Midlands et le South Yorkshire avec plus de 20 ans d'expérience dans le conseil sur les médicaments et les conditions médicales. Il possède une solide expérience en formation dans le domaine de la santé, ayant produit et dispensé des cours de formation pour les équipes de pharmacie et le personnel des établissements de soins résidentiels, y compris les infirmières. Il a également contribué aux comités consultatifs de pharmacie pour la gestion des affections de faible gravité dans la communauté.

À propos du critique

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Sid Dajani

Sultan Dajani a obtenu son diplôme à la London School of Pharmacy en 1994 et est devenu le plus jeune membre élu du conseil de la Royal Pharmaceutical Society depuis sa fondation en 1842.

Historique de l'article

Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.

  • Prochaine révision prévue : 9 mars 2027
  • 5 mai 2024 | Dernière version

    Dernière mise à jour par

    Michael Stewart, MRPharmS

    Revu par

    Sid Dajani
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