Clopidogrel pour prévenir les caillots sanguins
Plavix
Revu par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSDernière mise à jour 25 Apr 2024
Respecte les directives éditoriales
- TéléchargerTélécharger
- Partager
- Language
- Discussion
- Version audio
- Ajouter aux sources préférées sur Google
For people who have heart or blood vessel disease, taking clopidogrel each day can reduce the risk of heart attack and stroke.
Take one 75 mg tablet each day.
The most common side-effect is bleeding. If you cut yourself, it might take slightly longer than normal to stop the bleeding.
En un coup d'œil
Clopidogrel is an antiplatelet medicine that helps prevent blood clots.
It reduces the stickiness of platelets to lower the risk of heart attack or stroke.
Take one tablet daily at a time you can easily remember, with or without food.
Avoid medicines containing aspirin or anti-inflammatory painkillers unless advised by your doctor.
If you have an operation or dental treatment, tell the person treating you that you take clopidogrel.
Contact your doctor if you experience unusual or unexplained bleeding.
About clopidogrel
Type de médicament | An antiplatelet medicine |
Utilisé pour | To prevent clots from forming in blood vessels |
Aussi appelé | Plavix® |
Disponible sous forme de | Comprimés |
In your blood there are 'sticky' cells called platelets. When you cut yourself, the platelets stick to each other (clot) to seal the wound. Sometimes platelets stick to each other inside an artery - this is called a thrombus. A thrombus can block a blood vessel, and this is often the cause of a AVC ou crise cardiaque. This is more likely to happen if the walls of your arteries have areas which have become thickened with fat deposits, or if you have a fast irregular heartbeat.
If a thrombus forms in a blood vessel around your heart, this reduces the flow of blood to your heart. The term syndrome coronarien aigu (SCA) covers a range of disorders that are caused by this underlying problem. If you have been prescribed clopidogrel because you have ACS, it may mean that you have had a heart attack, or that you have angina pain that is not well controlled.
Clopidogrel reduces the stickiness of platelets, and this helps prevent the platelets from sticking to the inside of an artery and forming a thrombus. This reduces the risk of you having a heart attack or stroke.
Before taking clopidogrel
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking clopidogrel it is important that your doctor knows:
Si vous êtes enceinte ou si vous allaitez.
If you have a condition which causes bleeding (such as a stomach ulcer), or if you have recently had surgery or an injury.
Si vous avez des problèmes avec le fonctionnement de votre foie ou de vos reins.
Si vous avez déjà eu une réaction allergique à un médicament.
Si vous prenez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et les médecines complémentaires.
How to take clopidogrel
Before you start taking the tablets, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about clopidogrel and will provide you with a full list of the side-effects which you may experience from taking it.
Take the tablets exactly as your doctor tells you to. It is likely you will be prescribed one tablet of 75 mg clopidogrel to take each day. Although there are two strengths of clopidogrel tablets available (75 mg and 300 mg), the higher-strength tablet is only given as a first dose in some conditions.
You can take clopidogrel at whatever time of day you find easiest to remember, but take your doses at the same time of day each day. Most people prefer to take it in the morning, as they find this helps them to remember to take it regularly. You can take the tablet either before or after a meal.
If you forget to take a dose, take it as soon as you remember. If you do not remember until more than 12 hours after the time the dose should have been taken then skip the forgotten dose. Do not take two doses at the same time to make up for a missed dose.
Tirer le meilleur parti de votre traitement
Try to keep all your regular appointments with your doctor. This is so your doctor can check on your progress.
Before buying or taking any 'over-the-counter' medicines, check with your pharmacist whether the medicine is safe for you to take. You should not take any medicines which contain aspirin or any anti-inflammatory painkiller such as ibuprofen, unless your doctor has told you otherwise. This is because these medicines can increase the risk of bleeding when they are taken with clopidogrel. Many cold and flu remedies contain aspirin or ibuprofen.
If you are due to have an operation or dental treatment, tell the person carrying out the treatment that you are taking clopidogrel. This is because it is possible that any bleeding may take longer than normal to stop.
While you are on clopidogrel, it might take longer than normal to stop bleeding if you cut yourself. If this happens and you find it difficult to stop the bleeding, contact your doctor. Also, if you notice any unusual or unexplained bleeding, speak with your doctor about this too.
Can clopidogrel cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with clopidogrel. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common clopidogrel side-effects (these affect less than 1 in 10 people) | Que puis-je faire si je ressens cela ? |
Bleeding, nosebleeds, bruising, bleeding under the skin (blood blisters) | Because of the way clopidogrel works, any bleeding may take longer than normal to stop. If this becomes troublesome, let your doctor know |
Indigestion, tummy (abdominal) pain, diarrhoea | Optez pour des repas simples - évitez les aliments riches ou épicés |
Important : clopidogrel can occasionally cause unwanted effects which are more serious than the ones listed above. Although these occur only rarely, you should contact your doctor for advice if you feel generally unwell or if you experience any other symptoms which you think may be due to the tablets.
How to store clopidogrel
Gardez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.
Informations importantes sur tous les médicaments
Informations importantes sur tous les médicaments
Ne prenez jamais plus que la dose prescrite. Si vous soupçonnez que vous ou quelqu'un d'autre avez pris une surdose de ce médicament, rendez-vous au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.
Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Site web de Yellow Card.

Vous n'êtes pas sûr de mélanger des médicaments ?
Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.
Questions fréquemment posées
Can I take other medicines, including over-the-counter ones, with clopidogrel?
You should check with your pharmacist before taking any 'over-the-counter' medicines. It's particularly important to avoid medicines containing aspirin or anti-inflammatory painkillers like ibuprofen, as these can increase the risk of bleeding when taken with clopidogrel, unless specifically advised by your doctor. Many cold and flu remedies may contain these ingredients.
What should I do if I need surgery or dental treatment while taking clopidogrel?
If you are scheduled for any operation or dental treatment, you must inform the healthcare professional carrying out the procedure that you are taking clopidogrel. This is important because clopidogrel can cause any bleeding to take longer than usual to stop.
What are the common side effects of clopidogrel?
Common side effects, affecting less than 1 in 10 people, include bleeding, nosebleeds, bruising, and bleeding under the skin (blood blisters). Due to how clopidogrel works, any bleeding might take longer to stop. Other common side effects are indigestion, tummy pain, and diarrhoea. These often improve as your body adjusts to the medicine.
Should I be concerned about any rare but serious side effects?
Yes, clopidogrel can, on rare occasions, cause more serious unwanted effects. If you feel generally unwell or experience any other symptoms you think might be due to the tablets, you should contact your doctor for advice.
What should I do if I cut myself or notice unusual bleeding while on clopidogrel?
While taking clopidogrel, it might take longer than normal for bleeding to stop if you cut yourself. If you find it difficult to stop the bleeding, you should contact your doctor. Similarly, if you notice any unusual or unexplained bleeding, speak with your doctor about it.
Lectures complémentaires et références
- Manufacturer's PIL, Plavix® 75 mg tablets; Sanofi, The electronic Medicines Compendium. Dated December 2022.
- Médicaments Complets BNF 89e Édition; Association Médicale Britannique et Société Royale Pharmaceutique de Grande-Bretagne, Londres.
À propos de l'auteurVoir la biographie complète

Michael Stewart, MRPharmS
Responsable de l'examen des notices de médicaments – Contractuel, Pharmacien
BPharm (Hons), MRPharmS
Michael est un pharmacien communautaire exerçant dans les Midlands et le South Yorkshire avec plus de 20 ans d'expérience dans le conseil sur les médicaments et les conditions médicales. Il possède une solide expérience en formation dans le domaine de la santé, ayant produit et dispensé des cours de formation pour les équipes de pharmacie et le personnel des établissements de soins résidentiels, y compris les infirmières. Il a également contribué aux comités consultatifs de pharmacie pour la gestion des affections de faible gravité dans la communauté.
À propos du critique

Sid Dajani
Sultan Dajani a obtenu son diplôme à la London School of Pharmacy en 1994 et est devenu le plus jeune membre élu du conseil de la Royal Pharmaceutical Society depuis sa fondation en 1842.
Historique de l'article
Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.
Article également disponible en Anglais, Allemand, Espagnol, Français, Italien, Portugais, Hindi, Hébreu, Arabe, and Suédois.
Prochaine révision prévue : 21 févr. 2027
25 Apr 2024 | Dernière version

Demandez, partagez, connectez-vous.
Parcourez les discussions, posez des questions et partagez vos expériences sur des centaines de sujets de santé.
Inscrivez-vous à la newsletter Patient
Votre dose hebdomadaire de conseils de santé clairs et fiables - rédigés pour vous aider à vous sentir informé, confiant et maître de la situation.
En vous abonnant, vous acceptez notre Politique de confidentialité. Vous pouvez vous désabonner à tout moment. Nous ne vendons jamais vos données.
Plus sur le traitement et la prévention des maladies cardiaques
- Ambrisentan pour l'hypertension pulmonaire
- Aspirine pour prévenir les caillots sanguins
- Bisoprolol - un bêta-bloquant
- Comprimés de Bosentan
- Comprimés de Céliprolol
- Comprimés de Chlortalidone
- Comprimés d'éplérénone
- Comprimés de félodipine
- Dinitrate d'isosorbide
- Comprimés d'ivabradine
- Lisinopril - un inhibiteur de l'ECA
- Moxonidine pour l'hypertension artérielle
- Comprimés de nimodipine
- Comprimés de potassium
- Propafénone pour les battements de cœur irréguliers
- Ramipril - un inhibiteur de l'ECA
- Sildénafil pour l'hypertension artérielle pulmonaire
- Simvastatine
- Telmisartan - un bloqueur des récepteurs de l'angiotensine
- Warfarine - un anticoagulant