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Éthinylestradiol pour les symptômes de la ménopause ou les troubles menstruels

Clinical author's note Michael Stewart 18/8/2020: Ethinlyestradiol tablets were discontinued in the UK in July 2020. At the time of review there are no branded or generic products in the UK solely containing ethinylestradiol. It is still available in combination products for oral contraception. Ethinylestradiol may still be available in other countries. This medicine leaflet is based on medical information available in the UK at the time of writing and is left here for reference purposes. Please also refer to the manufacturer's information supplied with your medicine.

For information about ethinylestradiol in contraception please see our separate leaflet called Combined hormonal contraceptives.

Ethinylestradiol is taken in cycles. Make sure you know which days of the month to take a tablet, and which are tablet-free days. If you are uncertain, check with your doctor or pharmacist.

Do not rely on the tablets to prevent pregnancy - they are not intended to be used as a contraceptive.

Your doctor will discuss the benefits and risks of the treatment with you before you begin.

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About ethinylestradiol

Type de médicament

Un œstrogène (peut aussi être orthographié estrogène)

Utilisé pour

Hormone replacement therapy (HRT); menstrual problems

Disponible sous forme de

Tablets (discontinued)

Ethinylestradiol is a man-made form of the naturally occurring female hormone called oestrogen. It is prescribed to treat period (menstrual) problems, and also to help ease les symptômes de la ménopause. It is usually prescribed alongside another female hormone called a progestogen.

Ethinylestradiol is used to supplement or replace the body's natural oestrogen. It helps to relieve many of the problems associated with the menopause, such as hot flushes, night sweats and vaginal dryness. It can also help to protect against 'thinning' of the bones (osteoporosis) although other treatments are usually preferred for this.

This leaflet is appropriate if you have been prescribed ethinylestradiol for a menstrual disorder or for hormone replacement therapy (HRT). If you have been prescribed it for any other reason, please ask your doctor for further advice or refer to the manufacturer's printed information leaflet. Ethinylestradiol is also one of the hormones that are used in the contraceptive pill (the pill) - there is more information about this in a separate leaflet called Combined hormonal contraceptives.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking ethinylestradiol it is important that your doctor knows:

  • If you have any unexplained vaginal bleeding, or if you have ever had a problem with your womb such as fibroids, endometriosis, or endometrial hyperplasia (thickening of the lining of your womb).

  • If you have a heart condition or have had a stroke.

  • If you or a close family member have ever had a problem with a blood clot in a vein or artery.

  • Si vous avez eu un cancer du sein ou des nodules dans votre sein, ou si un membre proche de votre famille a eu un cancer du sein.

  • If you have any of the following: diabète (diabète sucré), gallstones, migraine, inflammatory bowel disease, systemic lupus erythematosis (SLE), or porphyria.

  • Si vous avez un problème avec le fonctionnement de votre foie.

  • If you have ever had depression.

  • If you have been told you have high levels of prolactin in your blood (hyperprolactinaemia).

  • If you or a close relative have ever had high levels of lipids in blood (hypertriglyceridaemia).

  • If you had any problems with jaundice, severe itchy blistering, or any involuntary muscle movements during a pregnancy.

  • If you could be pregnant or if you are breastfeeding.

  • Si vous prenez ou utilisez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et complémentaires.

  • Si vous avez déjà eu une réaction allergique à un médicament.

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  • Before you start this treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about ethinylestradiol and will provide you with a full list of the side-effects which you may experience from taking the tablets.

  • It is usual to take one dose of ethinylestradiol a day, although your doctor will ask you to take the tablets on certain days of the month only. It is usual to have 7-10 tablet-free days a month. It is important that you take ethinylestradiol exactly as your doctor tells you to. The directions will be printed on the label of the pack of tablets to remind you, but if there is anything you are still unsure about, ask your pharmacist if you need further advice.

  • Try to take the tablets at the same time of day as this will help you to remember to take your doses regularly. The tablets are easily swallowed with a drink of water.

  • Si vous oubliez de prendre une dose, prenez-la dès que vous vous en souvenez. Si vous ne vous en souvenez que le lendemain, sautez la dose oubliée. Ne prenez pas deux doses en même temps pour compenser une dose manquée.

  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. Also, regularly check your breasts for any lumps and remember to attend for any regular breast screening and cervical smear tests.

  • There are some risks which are associated with taking an oestrogen - your doctor will discuss the benefits and risks of the treatment with you before you start. The risks are reduced when small doses are used for short periods of time. If used for a long time the incidence of breast cancer and other adverse effects may increase. Because of this, the decision to continue the treatment needs to be made individually and your progress should be reviewed regularly. If you have any concerns at any time, make an appointment to discuss them with your doctor.

  • Travelling that involves long periods of immobility (more than three hours) can increase the risk of serious side-effects and in rare cases may lead to blood clots. Taking appropriate exercise during the journey and possibly wearing elastic hosiery can reduce this risk. If you would like more advice about this, speak with your doctor or pharmacist.

  • If you are due to have an operation, tell the person carrying out the surgery that you are taking an oestrogen, as you may be advised to stop the treatment for a while if you are likely to be on bed rest.

  • Do not rely on these tablets to prevent pregnancy - they are not intended to be used as a contraceptive. Your doctor will advise you about whether or not you need to use contraception. If at any time you suspect that you may be pregnant, stop taking ethinylestradiol and consult your doctor as soon as possible.

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Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with ethinylestradiol. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Ethinylestradiol side-effects

Que puis-je faire si je ressens cela ?

Sensation de malaise (nausée)

Eat simple meals (avoid rich or spicy foods).

Maux de tête

Ask your pharmacist to recommend a suitable painkiller. If the headache continues or is unusually severe, speak to your doctor as soon as possible.

Yeux secs

If you wear contact lenses, ask your optician for advice if this becomes troublesome.

Stomach cramps, bloating, weight changes, breast tenderness, fluid retention, rash, changes in sexual desire, mood changes, leg cramps, high blood pressure, kidney stones, menstrual bleeding or spotting

Speak with your doctor if any of these become troublesome.

Stop taking the tablets and contact your doctor for advice immédiatement if you develop any of the following symptoms:

  • Douleur thoracique soudaine.

  • Sudden breathlessness (or if you cough up blood).

  • Gonflement ou douleur dans une jambe.

  • Un mal de tête inhabituellement sévère.

  • Jaundice.

If you experience any other symptoms which you think may be due to this medicine, discuss them with your doctor or pharmacist.

  • Gardez tous les médicaments hors de la portée et de la vue des enfants.

  • Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.

Informations importantes sur tous les médicaments

Ne prenez jamais plus que la dose prescrite. Si vous soupçonnez que vous ou quelqu'un d'autre avez pris une surdose de ce médicament, rendez-vous au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.

Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.

Si vous achetez des médicaments, vérifiez avec un pharmacien qu'ils sont compatibles avec vos autres médicaments.

Si vous subissez une opération ou un traitement dentaire, informez la personne qui effectue le traitement des médicaments que vous prenez.

Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.

Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.

Signaler les effets secondaires d'un médicament ou d'un vaccin

Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Yellow Card website.

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Lectures complémentaires et références

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Historique de l'article

Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.

  • Next review due: 13 Aug 2026
  • 14 août 2023 | Dernière version

    Dernière mise à jour par

    Michael Stewart, MRPharmS

    Revu par

    Sid Dajani
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