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Oxcarbazépine pour l'épilepsie

Trileptal

Oxcarbazepine prevents fits (seizures).

Take it regularly, twice a day. Do not stop taking it unless your doctor tells you to.

It may cause you to feel sleepy, especially when you first start taking it.

At a glance

  • Oxcarbazepine is an antiepileptic medicine used to prevent seizures in epilepsy.

  • It stabilises the electrical activity in the brain to prevent seizures.

  • Take oxcarbazepine exactly as prescribed, usually twice a day.

  • Do not stop taking oxcarbazepine suddenly without consulting your doctor.

  • Inform your doctor if you experience mood changes or thoughts of self-harm.

  • Common side-effects include feeling sick, dizziness, and headache.

  • Seek medical help immediately for serious side-effects like high fever or severe skin rash.

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About oxcarbazepine

Type de médicament

Un médicament antiépileptique

Utilisé pour

Épilepsie

Aussi appelé

Trileptal®

Disponible sous forme de

Comprimés et médicaments liquides oraux

Having épilepsie means that you have had more than one otherwise unexplained fit, or seizure. A seizure is a short episode of symptoms caused by a burst of abnormal electrical activity in your brain. Different parts of the brain control different functions of your body, so the symptoms that occur during a seizure will depend on where the abnormal burst of electrical activity occurs. Symptoms that may occur during a seizure can affect your muscles, sensations, behaviour, emotions, consciousness, or a combination of these. The seizures can be prevented in most people by suitable antiepileptic medication. Oxcarbazepine works by stabilising the electrical activity of your brain, which prevents the seizures from occurring.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking oxcarbazepine it is important that your doctor knows:

  • Si vous êtes enceinte, essayez d'avoir un bébé ou allaitez.

  • If you have any problems with the way your kidneys work, or with the way your liver works.

  • Si vous avez une maladie cardiaque.

  • If you have been told you have low levels of sodium in your blood.

  • If you have a problem with your thyroid gland.

  • Si vous avez un trouble sanguin héréditaire rare appelé porphyrie.

  • Si vous prenez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et les médecines complémentaires.

  • Si vous avez déjà eu une réaction allergique à un médicament.

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  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about oxcarbazepine and will provide you with a full list of the side-effects which you may experience from taking it.

  • Take oxcarbazepine exactly as your doctor tells you to. It is usual to start treatment on a low dose, and then for the dose to be increased gradually to a regular maintenance dose. You will be asked to take two doses every day. Doses for children are tailored to their age and weight.

  • Try to take your doses at the same times of day, each day. Having a routine will help you to remember to take your doses regularly. If you have difficulties swallowing tablets whole, you can break them into halves to make them easier to swallow. Taking them with a drink of water also helps. You can take oxcarbazepine either before or after meals.

  • If you (or your child) have been given oxcarbazepine oral liquid medicine, make sure you understand how to measure the correct dose using the oral syringe provided. If you are unsure, ask your doctor, nurse or pharmacist to show you.

  • Si vous oubliez de prendre une dose, prenez-la dès que vous vous en souvenez, sauf si l'heure de votre prochaine dose approche, auquel cas ignorez la dose oubliée. Ne prenez pas deux doses en même temps pour compenser une dose oubliée.

  • Lorsque vous commencez un nouveau traitement pour l'épilepsie, il peut y avoir un changement dans le nombre ou le type de crises que vous ressentez. Votre médecin vous conseillera à ce sujet.

  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. You may need to have blood tests from time to time.

  • Different formulations and makes of oxcarbazepine can act in a slightly different way in your body. Because of this, your doctor may recommend that you continue to take oxcarbazepine from the same manufacturer each time you obtain a new supply. If so, each time you collect a prescription, check to make sure your supply looks the same and that the name is the same. If you are unsure, or if you have any questions about your prescription, please ask your pharmacist to advise you.

  • If you buy any medicines, check with a pharmacist that they are suitable for you to take. This is because some medicines interfere with oxcarbazepine, and oxcarbazepine can also alter the way other medicines work.

  • People with epilepsy must stop driving at first. Your doctor will advise you about when it may be possible for you to start driving again. This will usually be after a year free of seizures.

  • You should avoid getting pregnant, as antiepileptic medicines can harm an unborn child. Make sure you have discussed with your doctor which types of contraception are suitable for you and your partner. Oxcarbazepine may affect how well the hormonal contraceptive pill works and additional barrier methods (condoms) are recommended. If you want to have a family, discuss this with your doctor so that you can be given advice from a specialist avant you become pregnant.

  • Pendant que vous êtes traité pour l'épilepsie, il existe un petit risque que vous développiez des changements d'humeur, des pensées perturbantes et des sentiments suicidaires. Si cela se produit, vous devez en informer votre médecin immédiatement.

  • You need to take oxcarbazepine regularly every day. Do not stop taking it unless your doctor tells you to stop. Stopping treatment suddenly can cause problems and your doctor will want you to reduce your dose gradually if this becomes necessary.

  • If you drink alcohol, ask your doctor for advice. Your doctor may advise you not to drink alcohol while you are on this medicine.

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Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with oxcarbazepine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common oxcarbazepine side-effects

Que puis-je faire si je ressens cela ?

Feeling sick (nausea) or being sick (vomiting), tummy (abdominal) pain, diarrhoea or constipation

Try to stick to simple meals. Avoid rich and spicy food

Feeling dizzy, tired or sleepy; blurred or double vision

Ne conduisez pas et n'utilisez pas d'outils ou de machines

Maux de tête

Buvez beaucoup d'eau et demandez à votre pharmacien de vous recommander un antidouleur approprié. Si les maux de tête persistent, informez votre médecin

Mood changes such as feeling confused or depressed, weight gain, feeling unsteady, difficulty concentrating, forgetfulness, a spinning sensation (vertigo), skin rash, hair thinning, low sodium (your doctor will check for this) and acne

Si l'un de ces éléments devient problématique, consultez votre médecin pour obtenir des conseils

Important: your doctor will discuss with you the possibility that oxcarbazepine can cause liver, blood and skin disorders. Although these occur less commonly than the side-effects listed above, it is important that you contact your doctor straightaway if you experience any of the following symptoms:

  • Une température élevée (fièvre).

  • Extreme tiredness with confusion or muscle twitches.

  • Une éruption cutanée sévère.

  • Mouth ulcers.

  • Unexplained bruising or bleeding.

Si vous ressentez d'autres symptômes que vous pensez être dus au médicament, parlez-en à votre médecin ou à votre pharmacien pour obtenir des conseils supplémentaires.

  • Gardez tous les médicaments hors de la portée et de la vue des enfants.

  • Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.

  • Once a bottle of Trileptal® oral suspension has been opened, it should not be used or stored for more than seven weeks. After this time, get a new supply.

Informations importantes sur tous les médicaments

Ne prenez jamais plus que la dose prescrite. Si vous soupçonnez que vous ou quelqu'un d'autre avez pris une surdose de ce médicament, rendez-vous au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.

Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.

Si vous subissez une opération ou un traitement dentaire, informez la personne qui effectue le traitement des médicaments que vous prenez.

Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.

Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.

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Signalez les effets secondaires suspectés des médicaments, vaccins, cigarettes électroniques, incidents liés aux dispositifs médicaux, produits défectueux ou falsifiés (contrefaits) à l'Agence de Régulation des Médicaments et Produits de Santé pour garantir une utilisation sûre et efficace.

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Questions fréquemment posées

What is epilepsy and how does oxcarbazepine help?

Epilepsy is when you have had more than one unexplained fit or seizure. Seizures are caused by abnormal electrical activity in your brain, leading to symptoms that can affect muscles, sensations, behaviour, emotions, or consciousness. Oxcarbazepine works by stabilising this electrical activity in your brain, which helps to prevent these seizures from happening.

Can I take oxcarbazepine if I'm already taking other medications?

It's very important to tell your doctor about all medicines you are currently taking, including those bought without a prescription, as well as herbal and complementary medicines. Some medicines can interfere with oxcarbazepine, and oxcarbazepine can also change how other medicines work. Your doctor needs this information to decide if oxcarbazepine is suitable for you.

What should I do if I forget to take my oxcarbazepine dose?

If you miss a dose, take it as soon as you remember. However, if it's almost time for your next scheduled dose, you should skip the missed dose entirely. Do not take two doses at once to make up for the one you forgot, as this can cause problems.

Are there any specific instructions for taking oxcarbazepine oral liquid medicine?

If you or your child are using the oral liquid medicine, it's crucial to understand how to measure the correct dose using the provided oral syringe. If you are unsure at all, you should ask your doctor, nurse, or pharmacist to show you how to do it correctly.

How often will I need to see my doctor while taking oxcarbazepine?

You should keep your regular appointments with your doctor. These appointments are important so your doctor can monitor your progress and make sure the medication is working well for you. You may also need to have blood tests periodically.

Can oxcarbazepine affect my mood or thoughts?

While being treated for epilepsy with oxcarbazepine, there is a small risk that you might experience mood changes, distressing thoughts, or feelings about suicide. If you notice any of these changes, you must tell your doctor about them immediately.

What are some less common but serious side effects I should be aware of?

Though rarer than other side effects, oxcarbazepine can potentially cause liver, blood, and skin disorders. You must contact your doctor straight away if you experience a high temperature (fever), extreme tiredness with confusion or muscle twitches, a severe skin rash, mouth ulcers, or unexplained bruising or bleeding.

How should I dispose of old or unwanted oxcarbazepine medicine?

You should never keep out-of-date or unwanted medicines. The best way to dispose of them is to take them to your local pharmacy, which will handle their disposal properly for you.

Lectures complémentaires et références

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About the authorView full bio

Author image

Michael Stewart, MRPharmS

Medicine Leaflet Review Manager – Contractor, Pharmacist

BPharm (Hons), MRPharmS

Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.

About the reviewer

Author image

Sid Dajani

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

Historique de l'article

Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.

  • Prochaine révision prévue : 17 déc. 2026
  • 18 déc. 2023 | Dernière version

    Dernière mise à jour par

    Michael Stewart, MRPharmS

    Revu par

    Sid Dajani
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