Comprimés de Tétrabénazine

Xenazine

Revu par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSDernière mise à jour 14 avr. 2025

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The dose of tetrabenazine varies from person to person. Your doctor will tell you how you should take the tablets.

Swallow your doses with a drink of water. You can take tetrabenazine either before or after food.

Tetrabenazine can cause unwanted effects such as depression, feeling drowsy, slow muscle movements, and stiffness. Let your doctor know if this happens to you.

About tetrabenazine tablets

Utilisé pour	Troubles du mouvement
Aussi appelé	Xenazine®
Disponible sous forme de	Comprimés

Tetrabenazine acts on your brain and nervous system. It is used to treat uncontrolled jerky muscle movements associated with a conditions such as Huntington's chorea and tardive dyskinesia.

We do not know exactly how tetrabenazine works, but it is known to reduce the levels of a chemical in brain cells, called dopamine. Dopamine is involved in controlling our muscles so lower levels in the brain mean reduced muscle movements.

Before taking tetrabenazine tablets

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking tetrabenazine it is important that your doctor knows:

Si vous êtes enceinte ou si vous allaitez.
Si vous avez des problèmes avec le fonctionnement de votre foie, ou si vous avez des problèmes avec le fonctionnement de vos reins.
If you know you have problems with your heart rhythm.
If you have depression or thoughts of harming yourself.
If you have Parkinson-like symptoms.
If you have been told you have a tumour on your adrenal gland, called phaeochromocytoma, or if you have any other cancer.
Si vous prenez ou utilisez d'autres médicaments. Cela inclut tous les médicaments disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et les médecines complémentaires.
Si vous avez déjà eu une réaction allergique à un médicament.

How to take tetrabenazine tablets

Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about tetrabenazine, and will also provide you with a full list of the side-effects which you could experience from taking it.
Take tetrabenazine tablets exactly as your doctor tells you to. Your dose will be adjusted to suit your condition, so your doctor will tell you how many tablets to take each day. This information will also be printed on the label of the pack to remind you about what the doctor said to you. As a guide, you could be asked to take either one, two or three doses each day.
Swallow the tablet with a drink of water. You can take it either with or without food.
Try to take the tablets at the same time(s) each day, as this will help you to remember to take your doses regularly.
If you forget to take a dose, take it as soon as you remember (unless it is nearly time for your next dose, in which case leave out the missed dose and take the next dose as normal). Do not take two doses together to make up for a forgotten dose.

Tirer le meilleur parti de votre traitement

Essayez de respecter vos rendez-vous réguliers avec votre médecin. Cela permet à votre médecin de suivre vos progrès.
Treatment with tetrabenazine is usually long-term. Continue to take the tablets unless you are advised otherwise. Stopping suddenly can cause problems and your doctor may want you to reduce your dose gradually if this becomes necessary.
Tetrabenazine can cause you to feel drowsy. You should not drink alcohol as this can make the sleepiness worse.

Can tetrabenazine cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with tetrabenazine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common tetrabenazine side-effects (these affect more than 1 in 10 people)	Que puis-je faire si je ressens cela ?
Feeling depressed, unusual muscle movements	Speak with your doctor about either of these straightaway
Common tetrabenazine side-effects (these affect fewer than 1 in 10 people)	Que puis-je faire si je ressens cela ?
Se sentir somnolent ou endormi	Ne conduisez pas et n'utilisez pas d'outils ou de machines lorsque vous êtes affecté. Ne buvez pas d'alcool
Feeling dizzy or light-headed particularly when you get up (due to low blood pressure)	Getting up and moving more slowly may help. If you begin to feel dizzy, sit down and rest for a few minutes
Sensation de malaise (nausée), maux d'estomac	Optez pour des repas simples - évitez les aliments gras ou épicés
Feeling anxious or confused, difficulty sleeping, difficulty swallowing	Si l'un de ces éléments devient problématique, parlez-en à votre médecin

Important: si vous ressentez des symptômes tels que raideur musculaire, température très élevée (fièvre), confusion, rythme cardiaque rapide et transpiration, vous devez contacter votre médecin immédiatement. Ceux-ci peuvent être des signes d'une affection rare mais grave connue sous le nom de syndrome malin des neuroleptiques.

Si vous ressentez d'autres symptômes que vous pensez être dus aux comprimés, consultez votre médecin ou votre pharmacien pour obtenir des conseils supplémentaires.

How to store tetrabenazine

Gardez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur directe et de la lumière.

Informations importantes sur tous les médicaments

Ne prenez jamais plus que la dose prescrite. Si vous soupçonnez que vous ou quelqu'un d'autre avez pris une surdose de ce médicament, rendez-vous immédiatement au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.

Si vous subissez une opération ou un traitement dentaire, informez la personne qui effectue le traitement des médicaments que vous prenez.

Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.

If you buy any medicines 'over the counter', always check with a pharmacist that they are suitable to take with your prescribed medicines.

Do not keep-out-of date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.

Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.

Signaler les effets secondaires d'un médicament ou d'un vaccin

Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Site web de Yellow Card.

Questions fréquemment posées

Can tetrabenazine affect my emotions or mood?

Yes, feeling depressed is a very common side-effect of tetrabenazine, affecting more than 1 in 10 people. You should speak with your doctor straightaway if you experience this. It can also cause anxiety or confusion in some people, though less commonly.

What should I do if tetrabenazine makes me feel dizzy when I stand up?

Dizziness or feeling light-headed, particularly when getting up, can occur due to low blood pressure. Getting up and moving more slowly may help. If you start to feel dizzy, it's best to sit down and rest for a few minutes.

Are there any specific foods I should avoid while taking tetrabenazine if I experience stomach upset?

If you experience feeling sick (nausea) or stomach upset, it is recommended to stick to simple meals and avoid fatty or spicy foods.

What is neuroleptic malignant syndrome and what are its symptoms?

Neuroleptic malignant syndrome is a rare but serious condition. Symptoms include muscle stiffness, a very high temperature (fever), feeling confused, a fast heartbeat, and sweating. If you experience these, you should contact your doctor immediately.

Ces questions et réponses ont été générées à partir des informations de cet article.

Lectures complémentaires et références

Manufacturer's PIL, Tetrabenazine 25 mg Tablets; Ranbaxy (UK) Ltd (a Sun Pharmaceutical Company), The electronic Medicines Compendium. Dated March 2022.
Médicaments Complets BNF 89e Édition; Association Médicale Britannique et Société Royale Pharmaceutique de Grande-Bretagne, Londres.