Comprimés de fludrocortisone
Revu par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSDernière mise à jour 15 Sept 2022
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Fludrocortisone belongs to a class of medicines known as corticosteroids (more commonly called steroids).
You must take fludrocortisone each day.
If you need any medical treatment, make sure the person treating you knows you are taking fludrocortisone tablets.
Your pharmacist will give you a blue 'Steroid Treatment Card' - carry this with you at all times.
En un coup d'œil
Fludrocortisone is a corticosteroid medicine, also known as an oral steroid.
It replaces natural corticosteroids in people with Addison's disease or after adrenal gland removal.
It helps regulate blood pressure and blood salt level.
You will be given a 'Steroid Treatment Card' which you should carry at all times.
If you become ill, see your doctor straightaway.
Common side-effects include fluid retention and tummy pain.
About fludrocortisone
Type de médicament | Corticostéroïde |
Utilisé pour | Replacement treatment in people with Addison's disease or following surgical removal of the adrenal glands |
Aussi appelé | Fludrocortisone acetate |
Disponible sous forme de | Comprimés |
Fludrocortisone belongs to a group of medicines called corticosteroids. It is sometimes referred to simply as an stéroïde oral. It is used as a replacement treatment for people whose adrenal glands do not produce sufficient natural corticosteroids - a condition known as Maladie d'Addison. It is also used for people who have had surgery to remove their adrenal glands and who therefore no longer produce natural corticosteroids.
The two natural corticosteroids which need replacing are called hydrocortisone (cortisol) and aldosterone. The body's natural hydrocortisone can be replaced by taking hydrocortisone as a tablet or injection, but a substitute medicine has to be used to replace the body's natural aldosterone. Fludrocortisone is the substitute medicine used. It is used because its action in the body is similar to that of aldosterone. It will help to regulate your blood pressure and blood salt level.
Before taking fludrocortisone
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking fludrocortisone it is important that your doctor or pharmacist knows:
Si vous êtes enceinte ou si vous allaitez.
Si vous avez une hypertension artérielle (hypertension).
Si vous avez eu une crise cardiaque ou si vous avez d'autres problèmes cardiaques.
Si vous avez des problèmes de foie ou de reins.
If you (or anyone in your family) have diabetes or increased eye pressure (glaucoma).
Si vous avez des os fragilisés (ostéoporose).
Si vous avez une glande thyroïde sous-active.
Si vous avez déjà eu un problème de santé mentale - par exemple, la dépression.
Si vous avez de l'épilepsie.
Si vous avez eu un ulcère à l'estomac ou un trouble inflammatoire de l'intestin.
Si vous avez une quelconque infection, ou si vous avez déjà eu la tuberculose (TB).
Si vous (ou toute personne avec qui vous êtes en contact étroit) avez récemment eu la varicelle, la rougeole ou le zona.
Si vous avez déjà eu un caillot sanguin dans une artère ou une veine.
If you have a condition known as myasthenia gravis, which causes muscle weakness, or if you have ever developed muscle pain after taking a steroid medicine.
Si vous prenez d'autres médicaments, y compris ceux disponibles à l'achat sans ordonnance, ainsi que des médicaments à base de plantes et complémentaires.
Si vous avez déjà eu une réaction allergique à un médicament.
How to take fludrocortisone
Before starting this treatment, read the manufacturer's printed information leaflet from inside the pack and be careful to follow any printed instructions you have also been given. The leaflet will give you more information about fludrocortisone and a full list of side-effects which you may experience from taking it.
Your doctor or pharmacist will tell you how many tablets to take. This information will also be on the label of the packet of tablets to remind you. It is important that you take fludrocortisone exactly as your doctor has told you. It is usual to take fludrocortisone once daily, just after breakfast.
Try to take your dose at the same time each day, as this will help you to remember to take it. If you do forget to take a dose, take it as soon as you remember. If you do not remember until the following day, skip the missed dose. Do not take two doses together to make up for a forgotten dose.
Continue to take fludrocortisone tablets regularly each day - it is vital for your well-being. Fludrocortisone replacement treatment is almost always lifelong.
Tirer le meilleur parti de votre traitement
You will be given a 'Steroid Treatment Card' which says that you are on steroids and contains some important advice for you. It is important that you read this card and carry it with you at all times. It also contains details about your dose, the length of time you have been taking fludrocortisone, and who prescribed it for you. Please make sure that this information is kept up to date.
If you are having an operation or dental treatment or any treatment for an injury, tell the person carrying out the treatment that you are taking fludrocortisone and show them your treatment card.
Essayez de respecter vos rendez-vous réguliers avec votre médecin. Cela permet à votre médecin de suivre vos progrès. Votre médecin souhaitera que vous passiez des tests de temps en temps pour s'assurer que vous restez à l'abri de certains effets secondaires indésirables du traitement.
If you become ill it is important that you make an appointment to see your doctor straightaway. Also, if you come into contact with anyone who has measles, shingles or chickenpox (or anyone who suspects they might have them), you should see your doctor as soon as possible.
Make sure you get your next supply of tablets well in advance so that you never run out. People with Addison's disease are entitled to free NHS prescriptions.
Some vaccines may not be suitable for you. If you need any immunisations, make sure you mention that you are taking fludrocortisone.
Si vous avez besoin d'acheter des médicaments, vérifiez avec un pharmacien qu'ils sont compatibles avec vos autres médicaments.
'Thinning' of the bones (osteoporosis) is more common in people with Addison's disease compared to the general population. Regular exercise, a good diet and not smoking will all help to prevent the development of osteoporosis, or reduce its severity.
Can fludrocortisone cause problems?
Along with their useful effects, all medicines can cause unwanted side-effects although not everyone experiences them. The table below lists some of the more common side-effects associated with fludrocortisone treatment.You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects usually improve as your body adjusts to the new medicine, but other unwanted effects may develop with long-term fludrocortisone treatment. Speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.
Common fludrocortisone side-effects | Que puis-je faire si je ressens cela ? |
Rétention de liquide provoquant des pieds et chevilles enflés | Dans la mesure du possible, asseyez-vous les pieds en l'air |
Tummy (abdominal) pain, feeling sick (nausea) or bloated, indigestion | Stick to simple meals and avoid rich or spicy foods |
Faiblesse musculaire ou sensation de fatigue | If this happens, do not drive and do not use tools or machines until you feel better |
Changements d'humeur ou de comportement, surtout au début du traitement | If you become confused, anxious, irritable, have trouble sleeping or start having worrying thoughts about harming yourself, speak with your doctor as soon as possible |
Increased appetite or weight gain, irregular periods in women | Si l'un de ces éléments devient problématique, parlez-en à votre médecin |
Long-term treatment may cause other unwanted effects | Si vous avez des symptômes qui vous préoccupent, vous devriez prendre rendez-vous avec votre médecin pour obtenir des conseils |
Important: you should let your doctor know if you start to experience blurred vision or other vision problems whilst taking fludrocortisone.
Si vous ressentez d'autres symptômes que vous pensez être dus à ce médicament, discutez-en avec votre médecin ou votre pharmacien.
How to store fludrocortisone
Gardez tous les médicaments hors de la portée et de la vue des enfants.
Some brands of fludrocortisone tablet may need to be stored in a refrigerator (between 2°C and 8°C). Check the manufacturer's information that comes with your medicine.
Keep the container tightly closed.
Informations importantes sur tous les médicaments
Informations importantes sur tous les médicaments
Never take more than the prescribed dose. If you suspect that someone has taken an overdose of this medicine, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.
Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Site web de Yellow Card.

Vous n'êtes pas sûr de mélanger des médicaments ?
Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.
Questions fréquemment posées
Why do some people need to take fludrocortisone for their entire lives?
Fludrocortisone is a replacement treatment for people whose adrenal glands do not produce enough natural corticosteroids, either due to a condition like Addison's disease or because their adrenal glands have been surgically removed. Since the body needs these corticosteroids to regulate blood pressure and blood salt levels, and it cannot produce them itself in these cases, the treatment is almost always lifelong to maintain essential body functions.
What is a 'Steroid Treatment Card' and why is it important?
A 'Steroid Treatment Card' is given to you when you are on steroids like fludrocortisone. This card contains important advice and details about your dose, how long you've been taking the medicine, and who prescribed it. It is crucial to carry this card with you at all times, especially when undergoing any medical or dental treatment, or in an emergency, so healthcare professionals are aware of your steroid treatment.
What should I do if I think I've had an overdose of fludrocortisone?
If you suspect an overdose of fludrocortisone has occurred, you should go to the accident and emergency department of your local hospital immediately. Remember to take the medicine container with you, even if it is empty, as it will provide healthcare professionals with important information about the medication.
Since fludrocortisone is a steroid, does it increase my risk of osteoporosis?
While 'thinning' of the bones (osteoporosis) is more common in individuals with Addison's disease, the article does not directly state that fludrocortisone treatment itself causes or increases the risk of osteoporosis. Instead, it mentions that regular exercise, a good diet, and not smoking can help prevent or reduce the severity of osteoporosis, suggesting these are general preventative measures for those with Addison's disease.
What should I do if I notice blurred vision or other vision problems while taking fludrocortisone?
It is important that you let your doctor know if you start to experience blurred vision or any other vision problems while you are taking fludrocortisone. This specific symptom is highlighted as a concern that warrants immediate medical attention.
Lectures complémentaires et références
- Manufacturer's PIL, Fludrocortisone acetate 0.1 mg Tablets; Mylan, The electronic Medicines Compendium. Dated October 2021.
- Médicaments Complets BNF 89e Édition; Association Médicale Britannique et Société Royale Pharmaceutique de Grande-Bretagne, Londres.
À propos de l'auteurVoir la biographie complète

Michael Stewart, MRPharmS
Responsable de l'examen des notices de médicaments – Contractuel, Pharmacien
BPharm (Hons), MRPharmS
Michael est un pharmacien communautaire exerçant dans les Midlands et le South Yorkshire avec plus de 20 ans d'expérience dans le conseil sur les médicaments et les conditions médicales. Il possède une solide expérience en formation dans le domaine de la santé, ayant produit et dispensé des cours de formation pour les équipes de pharmacie et le personnel des établissements de soins résidentiels, y compris les infirmières. Il a également contribué aux comités consultatifs de pharmacie pour la gestion des affections de faible gravité dans la communauté.
À propos du critique

Sid Dajani
Sultan Dajani a obtenu son diplôme à la London School of Pharmacy en 1994 et est devenu le plus jeune membre élu du conseil de la Royal Pharmaceutical Society depuis sa fondation en 1842.
Historique de l'article
Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.
Article également disponible en Anglais, Allemand, Espagnol, Français, Italien, Portugais, Hindi, Hébreu, Arabe, and Suédois.
Prochaine révision prévue : 13 mars 2027
15 Sept 2022 | Dernière version

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