Méthyldopa pour l'hypertension artérielle
Aldomet
Revu par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSDernière mise à jour 15 janv. 2025
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Take methyldopa at the same times each day. It is usual to be prescribed two or three doses to take a day.
Methyldopa can make you feel sleepy, particularly during the first two or three days. Do not drive and do not use tools or machines while affected.
Continue to take methyldopa tablets until you are advised otherwise by your doctor.
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About methyldopa
Type de médicament | A centrally acting antihypertensive medicine |
Utilisé pour | Hypertension artérielle (hypertension) |
Aussi appelé | Aldomet® |
Disponible sous forme de | Comprimés |
Most people with hypertension artérielle (hypertension) do not feel unwell, but it is important that your high blood pressure is treated even if you feel fine. This is because high blood pressure can be damaging to your blood vessels and can put a strain on your heart. By lowering your blood pressure, methyldopa reduces your cardiovascular risk.
Methyldopa is one of the medicines of choice for treating high blood pressure in pregnancy. When taken during pregnancy, treatment with methyldopa is reviewed soon after the birth of the baby, as other treatment options are then likely to be more suitable.
Before taking methyldopa
Retour au sommaireSome medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking methyldopa it is important that your doctor knows:
Si vous avez des problèmes avec le fonctionnement de votre foie, ou des problèmes avec le fonctionnement de vos reins.
Si vous avez déjà eu une maladie dépressive.
If you have been told you have any of the following rare conditions: an adrenaline-producing growth called a phaeochromocytoma or a paraganglioma, or an inherited blood disorder called porphyria.
Si vous prenez ou utilisez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et complémentaires.
Si vous avez déjà eu une réaction allergique à un médicament.
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How to take methyldopa
Retour au sommaireBefore you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about methyldopa and will provide you with a full list of the side-effects which you may experience from taking it.
Take methyldopa exactly as your doctor tells you to. It is usual to start by taking 250 mg two or three times daily. Your doctor may increase your dose after a few days if it is necessary. Each time you see your doctor you will be told how many tablets to take for each dose, and this information will also be printed on the label of the pack of tablets to remind you about what the doctor said to you.
Try to take your doses at the same times of day each day, as this will help you to remember to take them regularly. You can take your doses either before or after food. Swallow the tablet with a drink of water.
If you forget to take a dose, take it as soon as you remember. Try to take the correct number of doses each day but do not take two doses at the same time to make up for a missed dose.
Tirer le meilleur parti de votre traitement
Retour au sommaireTry to keep your regular appointments with your doctor so your progress can be monitored. Your doctor will want you to have blood tests from time to time to make sure your liver is working properly.
There are three strengths of methyldopa tablet available - 125 mg, 250 mg and 500 mg. Each time you collect a fresh supply of tablets it is a good idea to check to make sure you receive the strength you are expecting. If you have any questions, please ask your pharmacist to advise you.
Your doctor may give you dietary and lifestyle advice about eating a healthy diet, not smoking, and taking regular exercise. If so, it is important that you follow the advice you are given.
Drinking alcohol while you are on methyldopa is not recommended. It can increase the chance that you will experience side-effects, such as feeling sleepy or dizzy.
If you buy any medicines 'over the counter', please check with a pharmacist that they are suitable for you to take with methyldopa. Some medicines, such as some anti-inflammatory painkillers, can interfere with the way methyldopa works.
If you are due to have an operation or dental treatment, tell the person carrying out the treatment that you are taking methyldopa. This is because some anaesthetics can affect your blood pressure. Also, before having any medical tests, tell the person carrying out the test that you are taking methyldopa, as the results of some tests can be affected by it.
Continue to take methyldopa tablets until you are advised otherwise by your doctor.
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Can methyldopa cause problems?
Retour au sommaireAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the common ones associated with methyldopa. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common methyldopa side-effects | Que puis-je faire si je ressens cela ? |
Feeling sleepy, weak, or tired | This can happen during the first few days of treatment and if your dose is increased. Increase your evening dose first. Do not drive and do not use tools or machines while affected. Do not drink alcohol |
Maux de tête | Buvez beaucoup d'eau et demandez à votre pharmacien de vous recommander un antidouleur approprié. Si les maux de tête persistent, informez votre médecin |
Important: if you develop a high temperature which you can't explain, or if you notice any yellowing of your skin or of the whites of your eyes (jaundice), speak with your doctor as soon as possible. Occasionally, some people taking methyldopa have had blood or liver problems and your doctor will want you to have a blood test to check for these.
Si vous ressentez d'autres symptômes que vous pensez être dus aux comprimés, parlez-en à votre médecin ou à votre pharmacien pour obtenir des conseils supplémentaires.
How to store methyldopa
Retour au sommaireGardez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.
Informations importantes sur tous les médicaments
Retour au sommaireInformations importantes sur tous les médicaments
Ne prenez jamais plus que la dose prescrite. Si vous soupçonnez que vous ou quelqu'un d'autre avez pris une surdose de ce médicament, rendez-vous au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.
Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le site web Yellow Card.

Vous n'êtes pas sûr de mélanger des médicaments ?
Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.
Lectures complémentaires et références
- Manufacturer's PIL, Aldomet® Tablets 250 mg and 500 mg; Aspen Pharma Trading Ltd, The electronic Medicines Compendium. Dated April 2022.
- Médicaments Complets BNF 89e Édition; Association Médicale Britannique et Société Royale Pharmaceutique de Grande-Bretagne, Londres.
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Historique de l'article
Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.
Next review due: 15 Jan 2028
15 janv. 2025 | Dernière version

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