Prednisolone
Dilacort
Revu par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSLast updated 29 mai 2023
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Prednisolone belongs to a class of medicines known as corticosteroids (more commonly called steroids).
Your pharmacist will give you a blue steroid treatment card if you need to take prednisolone for more than a few weeks. Carry this with you at all times.
If you need any medical treatment, make sure the person treating you knows you are taking prednisolone. This is because your dose may need to be increased for a short while.
At a glance
Prednisolone is a steroid medicine used to treat inflammatory and allergic conditions.
It is available as tablets, oral solution, and injections.
Take prednisolone once daily in the morning after breakfast, usually with food.
Always carry your steroid treatment card if you use prednisolone for more than three weeks.
If you have diabetes, prednisolone may affect your blood sugar levels.
Do not stop taking prednisolone suddenly if you have been on it for more than three weeks.
See your doctor immediately if you get ill or come into contact with measles, shingles, or chickenpox.
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About prednisolone
Type de médicament | Corticostéroïde |
Utilisé pour | To help control inflammatory and allergic conditions such as asthma, rheumatoid arthritis and colitis |
Aussi appelé | Dilacort® |
Disponible sous forme de | Tablets, enteric-coated tablets (these are also known as gastro-resistant tablets), soluble tablets, oral solution and injection |
Prednisolone belongs to a group of medicines called corticosteroids. It is sometimes referred to as an oral steroid, or simply, a steroid. Oral steroids are used to treat a large number of conditions. Some examples include: asthme, inflammatory bowel diseases (for example, maladie de Crohn, la colite ulcéreuse), autoimmune diseases (for example, lupus érythémateux systémique (LES), sarcïdose), joint and muscle diseases (for example, polyarthrite rhumatoïde), and allergies. They are also used in the treatment of some cancers. Steroids work in part by suppressing your body's immune system, and this reduces swelling and inflammation.
There are also a number of separate medicine leaflets available which provide information about other formulations of prednisolone. These are called Mousse rectale, lavement et suppositoires de prednisolone, Gouttes ophtalmiques de prednisolone pour l'inflammation, and Gouttes auriculaires de prednisolone.
Before taking prednisolone
Retour au sommaireSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking prednisolone it is important that your doctor knows:
Si vous êtes enceinte, essayez d'avoir un bébé ou allaitez.
Si vous avez de l'hypertension.
If you have had a heart attack or have any other heart problems.
Si vous avez des problèmes de foie ou de reins.
If you (or anyone in your family) have diabetes mellitus or increased eye pressure (glaucoma).
If you have weakened bones (osteoporosis).
Si vous avez une glande thyroïde sous-active.
If you have ever had a mental health problem, such as depression or psychosis.
Si vous avez de l'épilepsie.
If you have had a stomach ulcer or an inflammatory bowel disorder.
Si vous avez récemment reçu, ou êtes sur le point de recevoir, des vaccinations.
If you have any kind of infection, or if you have ever had tuberculosis (TB).
If you (or anyone you are in close contact with) have recently had chickenpox, measles or shingles.
If you have ever had a blood clot in an artery or vein.
If you have myasthenia gravis (this is a condition causing muscle weakness).
Si vous prenez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et les médecines complémentaires.
If you have had an allergic reaction to a medicine, or if you have developed muscle pain after taking a steroid medicine.
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How to take prednisolone
Retour au sommaireBefore starting this treatment, read the manufacturer's printed information leaflet from inside the pack, and also any other printed information you have been given by your doctor or pharmacist. The manufacturer's leaflet will give you more information about prednisolone and a full list of side-effects which you may experience from taking it.
Your doctor or pharmacist will tell you how many tablets to take for each dose. It is usual to take prednisolone once daily, in the morning after breakfast.
Most prednisolone tablets should be taken with food. The food helps to protect the lining of your stomach from any irritation. If you have been given enteric-coated tablets (these are red or brown), these tablets are specially coated to help protect your stomach and can be taken either before or after food.
Enteric-coated (red or brown) tablets should be swallowed whole - do not chew or crush them. Also, it is important that you do not take any indigestion remedies (such as an antacid) during the two hours before you take a dose or during the two hours after you have taken a dose. This is because they interfere with the special coating on your tablets.
Some prednisolone tablets can be taken dissolved in water. If you have any difficulties swallowing, ask your doctor if this type of tablet would be more suitable for you.
Depending upon the reason why you are prescribed prednisolone, you may be asked to take a short course (for five days or so), or on a regular basis for a longer period of time. Continue to take prednisolone regularly until your doctor tells you to stop. If you take prednisolone for more than about three weeks, stopping treatment suddenly can cause problems, so your doctor will reduce your dose gradually when necessary.
Si vous oubliez de prendre une dose, prenez-la dès que vous vous en souvenez. Si vous ne vous en souvenez que le lendemain, sautez la dose oubliée. Ne prenez pas deux doses ensemble pour compenser une dose oubliée.
Tirer le meilleur parti de votre traitement
Retour au sommaireIf you are prescribed prednisolone for more than three weeks, you will be given a 'steroid treatment card' which says that you are on steroids and contains some important advice for you. It is important that you read this card and carry it with you at all times. It also contains details about your dose, how long you have been taking prednisolone, and who prescribed it for you. Please make sure that this information is kept up-to-date. If you are having an operation or dental treatment or any treatment for an injury, tell the person carrying out the treatment that you are taking prednisolone and show them your treatment card. This is because your dose may need adjusting.
Essayez de respecter vos rendez-vous réguliers avec votre médecin. Cela permet à votre médecin de suivre vos progrès. Votre médecin souhaitera que vous passiez des tests de temps en temps pour s'assurer que vous restez à l'abri de certains effets secondaires indésirables du traitement.
Prednisolone can suppress your immune system, so it is important if you become ill that you make an appointment to see your doctor straightaway. Also, if you come into contact with anyone who has measles, shingles or chickenpox (or anyone who suspects they might have them), you doivent see your doctor as soon as possible.
If you have diabetes you may need to check your blood sugar (glucose) more frequently, as prednisolone tablets may affect the levels of sugar in your blood. Your doctor will be able to advise you about this.
Some vaccines are not suitable for you while you are being treated with prednisolone. If you need any immunisations, make sure you mention that you are taking an oral steroid.
If you buy any medicines, check with your pharmacist that they are suitable for you to take with prednisolone. Some anti-inflammatory painkillers (such as ibuprofen) can increase the risk of side-effects and may not be suitable.
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Can prednisolone cause problems?
Retour au sommaireAlong with its useful effects, prednisolone can cause unwanted side-effects which your doctor will discuss with you. The benefits of taking prednisolone usually outweigh the side-effects, although unwanted effects can sometimes be troublesome. The table below contains some of the most common ones. You will find a full list in the manufacturer's information leaflet supplied with your medicine. Although not everyone experiences side-effects, and some will improve as your body adjusts to the new medicine, you should speak with your doctor or pharmacist if you become concerned about any of the following:
Common prednisolone side-effects | Que puis-je faire si je ressens cela ? |
Douleur abdominale, indigestion, sensation de malaise (nausée) | Stick to simple meals - avoid rich or spicy food. If you are sick (vomit) and there is blood present, you should speak with your doctor straightaway |
Mood or behaviour changes, especially at the beginning of treatment | If you become confused, irritable or start having worrying thoughts about harming yourself, speak with your doctor as soon as possible |
Difficulties sleeping, feeling confused, increased weight, thrush, muscle weakness, feeling tired, irregular periods | Si l'un de ces éléments devient problématique, parlez-en à votre médecin |
Long-term treatment with prednisolone may cause other unwanted effects | Si vous présentez des symptômes qui vous préoccupent, vous devriez prendre rendez-vous avec votre médecin pour obtenir des conseils |
For more information about side-effects which are possible when prednisolone is taken long-term, see the separate leaflet called Oral Steroids.
How to store prednisolone
Retour au sommaireGardez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.
Informations importantes sur tous les médicaments
Retour au sommaireInformations importantes sur tous les médicaments
Ne prenez jamais plus que la dose prescrite. Si vous soupçonnez que vous ou quelqu'un d'autre avez pris une surdose de ce médicament, rendez-vous au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.
Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Yellow Card website.

Vous n'êtes pas sûr de mélanger des médicaments ?
Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.
Questions fréquemment posées
What is prednisolone used for?
Prednisolone is a type of corticosteroid, sometimes called an oral steroid. It is used to treat a variety of inflammatory and allergic conditions such as asthma, inflammatory bowel diseases, autoimmune diseases like SLE, rheumatoid arthritis, and certain allergies. It also has uses in treating some cancers. Its primary function is to suppress the immune system, thereby reducing swelling and inflammation.
Are there different forms of prednisolone?
Yes, prednisolone is available in different forms including tablets, enteric-coated tablets (also known as gastro-resistant tablets), soluble tablets, oral solutions, and injections. There are also specific formulations for rectal use, eye drops, and ear drops.
Can I take indigestion remedies with prednisolone?
If you are taking enteric-coated (red or brown) prednisolone tablets, you should not take any indigestion remedies, such as an antacid, during the two hours before or the two hours after taking your prednisolone dose. This is because indigestion remedies can interfere with the special coating on these tablets.
What should I do if I typically have trouble swallowing pills?
If you have difficulty swallowing tablets, you can ask your doctor if a soluble form of prednisolone would be more suitable for you, as some types can be dissolved in water.
What if I forget to take a dose of prednisolone?
If you forget to take your prednisolone dose, take it as soon as you remember. However, if you don't remember until the following day, you should skip the missed dose. Do not take two doses together to try and compensate for the forgotten dose.
Why is it important to carry a 'steroid treatment card'?
If you are prescribed prednisolone for more than three weeks, you will receive a 'steroid treatment card'. This card states that you are on steroids and provides important advice. It helps healthcare professionals know about your medication if you need an operation, dental treatment, or treatment for an injury, as your dose may need adjustment.
Can prednisolone affect my blood sugar levels?
Yes, if you have diabetes, prednisolone tablets may affect your blood sugar (glucose) levels. You might need to check your blood sugar more frequently, and your doctor can provide guidance on this.
Are there any over-the-counter medicines I should avoid while taking prednisolone?
Yes, you should check with your pharmacist if any over-the-counter medicines are suitable to take with prednisolone. Some anti-inflammatory painkillers, such as ibuprofen, can increase the risk of side-effects and may not be suitable.
Lectures complémentaires et références
- Manufacturer's PIL, Prednisolone 2.5 mg and 5 mg gastro-resistant tablets; Phoenix Labs Ltd, The electronic Medicines Compendium. Dated June 2020.
- Manufacturer's PIL, Prednisolone Tablets 1 mg, 5 mg; Wockhardt UK Ltd, The electronic Medicines Compendium. Dated January 2023.
- Médicaments Complets BNF 89e Édition; Association Médicale Britannique et Société Royale Pharmaceutique de Grande-Bretagne, Londres.
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About the authorView full bio

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Historique de l'article
Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.
Prochaine révision prévue : 28 nov. 2027
29 mai 2023 | Dernière version

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