Prométhazine
Avomine, Phenergan, Sominex
Revu par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSDernière mise à jour 18 Mar 2023
Respecte les directives éditoriales
- TéléchargerTélécharger
- Partager
- Language
- Discussion
- Version audio
Promethazine is an antihistamine.
You may need to take one or more doses during a day, depending upon the reason you are taking it. Make sure you carefully follow the directions on the label.
Promethazine may affect your ability to drive and to use tools or machines.
The most common side-effects are feeling sleepy, headache, dry mouth and blurred vision.
Dans cet article:
Sélections de vidéos pour Médicaments contre les allergies
Continuez à lire ci-dessous
About promethazine
Type de médicament | An antihistamine |
Utilisé pour | Allergic conditions such as hay fever; to prevent sickness (nausea); and as a sedative |
Aussi appelé | Avomine®, Vertigon® (promethazine teoclate); Phenergan®, Sominex® (promethazine hydrochloride) |
Disponible sous forme de | Comprimés, médicament liquide oral et injection |
Promethazine belongs to a group of medicines known as sedating antihistaminiques. It has several uses.
It is used to prevent (or treat) feelings of sickness (nausea). It is commonly recommended for sickness associated with travel and for vertige.
It is also used to relieve allergies such as rhume des foins et allergic skin rashes.
Promethazine also makes you feel sleepy (has a sedative effect). It may be taken (for a few days only) to help promote sleep in adults with sleeping problems. It has been popular in the past as a means of 'settling' children, but promethazine should not be used in this way.
Promethazine is available on prescription, or you can buy it without a prescription at pharmacies. It is not suitable for children under 2 years of age.
Before taking promethazine
Retour au sommaireTo make sure this is the right treatment for you, before you start taking promethazine it is important that you discuss the treatment with a doctor or pharmacist if:
You are pregnant, trying for a baby or breastfeeding.
You have a problem with the way your liver works, or if you have a problem with your kidneys.
You have a slow or irregular heartbeat.
You have a condition which causes increased pressure in your eyes, such as glaucoma.
You have prostate problems or if you have been experiencing any difficulty passing urine.
You know you have a blockage in your small intestines.
You have epilepsy.
You have any long-term breathing problems, such as asthma or chronic obstructive pulmonary disease (COPD).
You have a low level of potassium in your blood (hypokalaemia).
You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines.
You have ever had an allergic reaction to a medicine.
Continuez à lire ci-dessous
How to take promethazine
Retour au sommaireBefore you start this treatment, read the manufacturer's printed information leaflet from inside your pack. There are a number of different brands and strengths of promethazine tablet. The manufacturer's leaflet will give you more information about the brand you have been given. It will also contain a full list of the side-effects which you may experience from taking promethazine.
Take promethazine exactly as your doctor or pharmacist has told you to. You may be asked to take one or more doses during a day, depending upon the reason why you are taking it.
If you are taking promethazine to prevent travel sickness, it is usually recommended that you take the first dose at bedtime on the evening before you are due to travel. You can then take a further dose on the morning of your travel if needed.
You can take promethazine before or after meals. Some people find it helps to swallow the tablets with a drink of water.
If you are giving promethazine liquid medicine to a child, make sure you follow the dosing instructions on the bottle carefully so that you measure out the correct dose for the age of your child.
Most people only need to take an antihistamine for a short while when they have symptoms. You should stop taking promethazine once your symptoms have eased. Do not take promethazine for more than a few days for sleeping problems.
Tirer le meilleur parti de votre traitement
Retour au sommairePromethazine may cause drowsiness and blurred vision. If this happens to you, do not drive and do not use tools or machines. Alcohol will make the drowsiness worse, so it is best not to drink alcohol while you are on promethazine.
If you are pregnant, only take promethazine on the advice of your doctor. Do not take promethazine in the last two weeks before your baby is born as it could cause side-effects for your baby.
If you are having an operation or any treatment (particularly if it is to test for an allergy), tell the person carrying out the treatment that you are taking promethazine.
Promethazine may cause your skin to become more sensitive to sunlight than normal. Use a sunscreen that protects against UVA light and has a sun protection factor (SPF) of at least 15, especially in strong sunlight or until you know how your skin reacts. Do not use sunbeds.
If you buy any medicines, check with a pharmacist that they are safe to take with an antihistamine. This is because a number of other medicines can interfere with the way promethazine works and can increase the risk of side-effects.
Continuez à lire ci-dessous
Can promethazine cause problems?
Retour au sommaireAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains the most common ones associated with promethazine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any continue or become troublesome.
Effets secondaires courants promethazine side-effects | Que puis-je faire si je ressens cela ? |
Feeling dizzy or sleepy, and blurred vision | Ne conduisez pas et n'utilisez pas d'outils ou de machines. Ne buvez pas d'alcool |
Maux de tête | Drink plenty of water and ask your pharmacist to recommend a suitable painkiller. If the headaches continue, stop taking promethazine or speak with your doctor |
Bouche sèche | Try sucking sugar-free sweets or chewing sugar-free gum |
Difficulty passing urine | Speak with your doctor if this becomes troublesome |
Stomach upset, constipation | Try to eat a well-balanced diet and drink plenty of water |
Si vous ressentez d'autres symptômes que vous pensez être dus à ce médicament, parlez-en à votre médecin ou à votre pharmacien.
How to store promethazine
Retour au sommaireGardez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur directe et de la lumière.
Informations importantes sur tous les médicaments
Retour au sommaireInformations importantes sur tous les médicaments
Ne prenez jamais plus que la dose prescrite. Si vous soupçonnez que vous ou quelqu'un d'autre avez pris une surdose de ce médicament, rendez-vous au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.
Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le site web Yellow Card.

Vous n'êtes pas sûr de mélanger des médicaments ?
Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.
Lectures complémentaires et références
- Manufacturer's PIL, Phenergan® 10 mg Tablets; Sanofi, The electronic Medicines Compendium. Dated October 2021.
- Manufacturer's PIL, Sominex® 20 mg Tablets; Teva UK Ltd, The electronic Medicines Compendium. Dated May 2022.
- Médicaments Complets BNF 89e Édition; Association Médicale Britannique et Société Royale Pharmaceutique de Grande-Bretagne, Londres.
Continuez à lire ci-dessous
Historique de l'article
Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.
Next review due: 17 Mar 2026
18 Mar 2023 | Dernière version

Demandez, partagez, connectez-vous.
Parcourez les discussions, posez des questions et partagez vos expériences sur des centaines de sujets de santé.
Inscrivez-vous à la newsletter Patient
Votre dose hebdomadaire de conseils de santé clairs et fiables - rédigés pour vous aider à vous sentir informé, confiant et maître de la situation.
En vous abonnant, vous acceptez notre Politique de confidentialité. Vous pouvez vous désabonner à tout moment. Nous ne vendons jamais vos données.