Gélules de célécoxib pour la douleur et l'inflammation

About celecoxib

Anti-inflammatory painkillers like celecoxib are sometimes called non-steroidal anti-inflammatory drugs (NSAIDs), or just 'anti-inflammatories'. Celecoxib is used to treat painful rheumatic conditions such as osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. It eases pain and reduces inflammation.

Celecoxib is also known as a cyclo-oxygenase-2 inhibitor. This is because it works to relieve pain and inflammation by blocking an enzyme in the body called cyclo-oxygenase-2 (COX-2). COX-2 is involved in the production of irritant substances in the body in response to disease. By blocking the action of COX-2, celecoxib reduces the symptoms of pain and inflammation in arthritis.

Before taking celecoxib

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking celecoxib, it is important that your doctor knows:

• Si vous souffrez d'asthme ou de tout autre trouble allergique.

• If you have had a stomach or duodenal ulcer, or if you have an inflammatory bowel disorder such as Crohn's disease or ulcerative colitis.

• Si vous êtes enceinte, si vous essayez d'avoir un enfant ou si vous allaitez.

• Si vous avez moins de 18 ans ou plus de 65 ans.

• Si vous avez des problèmes hépatiques ou rénaux.

• Si vous souffrez d'une maladie cardiaque ou d'un problème de vaisseaux sanguins ou de circulation.

• Si vous souffrez d'hypertension artérielle.

• Si vous avez déjà eu des problèmes de coagulation sanguine.

• Si vous souffrez d'une maladie du tissu conjonctif, telle que le lupus érythémateux disséminé (une maladie inflammatoire également appelée lupus ou LED).

• Si vous prenez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles sans ordonnance, ainsi que les médicaments à base de plantes et les médicaments complémentaires.

• If you have ever had an allergic reaction to a medicine. It is particularly important that you tell your doctor if you have ever had a bad reaction to any other NSAID (such as aspirin, naproxen, diclofenac, and indometacin), or if you are allergic to a sulfonamide medicine (used to treat infection).

How to take celecoxib

• Before you start taking celecoxib, read the manufacturer's printed information leaflet from inside the pack. The manufacturer's leaflet will give you more information about celecoxib and provide a full list of side-effects which you may experience from taking it.

• Take celecoxib exactly as your doctor tells you to. The usual dose is one capsule, taken once or twice daily. There are two strengths of capsule available, 100 mg and 200 mg - your doctor will tell you which is right for you. Try to take your doses at the same times of day each day, as this will help you to remember to take the capsules regularly.

• Swallow the capsules whole with a drink of water. If you have difficulty swallowing the capsules they can be opened and the entire contents sprinkled on to a spoonful of soft food such as apple sauce, yoghurt or mashed banana. Swallow the mixture straightaway, followed by drinking a large glass of water.

• It is not important whether you take your doses before or after meals.

• Si vous oubliez de prendre une dose, prenez-la dès que vous vous en rendez compte, sauf s'il est presque temps de prendre la dose suivante, auquel cas ne prenez pas la dose oubliée. Ne prenez pas deux doses en même temps pour compenser une dose oubliée.

Tirer le meilleur parti de votre traitement

• Your doctor will try to prescribe you the lowest dose for the shortest time to reduce the risk of side-effects. If you need to take celecoxib for a long time, your doctor may want to prescribe another medicine along with it to protect your stomach from irritation.

• Try to keep any regular appointments with your doctor. This is so your doctor can check on your progress. Your doctor will want to check your blood pressure from time to time while you are taking celecoxib.

• You should find that your pain is eased within a few days of starting to take the capsules. If after two weeks you find your pain is no better despite taking celecoxib, you should discuss this with your doctor, as an alternative painkiller may be more suitable for you.

• If you have asthma, symptoms such as wheeze or breathlessness can be made worse by anti-inflammatories such as celecoxib. If this happens to you, you should stop taking celecoxib and see your doctor as soon as possible.

• If you buy any medicines, check with a pharmacist that they are safe to take with an anti-inflammatory like celecoxib. This is because you should not take celecoxib with any other anti-inflammatory painkiller, some of which are available in cold and flu remedies which can be bought over the counter.

• Si vous devez subir une opération ou un traitement dentaire, indiquez à la personne chargée du traitement les médicaments que vous prenez.

Can celecoxib cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with celecoxib. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Important: if you experience any of the following less common but more serious symptoms, stop taking celecoxib and contact your doctor for advice straightaway:

• Si vous avez des difficultés respiratoires telles qu'une respiration sifflante ou un essoufflement.

• Si vous présentez des signes de réaction allergique, tels qu'un gonflement autour de la bouche ou du visage, ou une éruption cutanée accompagnée de fortes démangeaisons.

• If you pass blood or black stools, bring up (vomit) blood, or have abdominal pains.

Si vous ressentez d'autres symptômes qui pourraient être dus à ce médicament, parlez-en à votre médecin ou à votre pharmacien.

How to store celecoxib

• Conservez tous les médicaments hors de la portée et de la vue des enfants.

• Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.
  

Informations importantes sur tous les médicaments