Codéine pour le soulagement de la douleur
Revu par Dr Colin Tidy, MRCGPDernière mise à jour par Michael Stewart, MRPharmSDernière mise à jour 18 déc. 2023
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This medicine is an opioid painkiller. There is a serious risk of addiction when taking this medicine, especially if used long-term. The Medicines and Healthcare products Regulatory Agency (MHRA) has issued new guidance for people prescribed an opioid painkiller. If you have any questions or concerns about taking opioids safely please speak with your doctor or a pharmacist.
Codeine is used to treat mild-to-moderate types of pain.
The most common side effects of codeine are feeling sick (nausea), constipation, feeling sleepy, and dry mouth.
Codeine may affect your reactions. When you first start treatment, do not drive until you know how you react.
Dans cet article:
Sélections de vidéos pour Analgésiques et médicaments contre la douleur
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About codeine
Type de médicament | An opioid painkiller (analgesic) |
Utilisé pour | Soulagement de la douleur |
Aussi appelé | Codeine phosphate |
Disponible sous forme de | Comprimés, médicament liquide oral et injection |
What is codeine used for?
Retour au sommaireCodeine is a type of opioid (a strong painkiller) that is used to treat mild-to-moderate types of pain. It can be particularly useful when painkillers such as paracétamol et ibuprofène have not been effective.
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How does codeine work?
Retour au sommaireCodeine works by binding to certain tiny areas, called opioid receptors, in your central nervous system (brain and spinal cord). This leads to a decrease in the way you feel pain and your reaction to pain.
Where can you get codeine from?
Retour au sommaireCodeine is available with a prescription from a doctor. It is also included in some pain relief medicines you can buy directly from a pharmacy without a prescription. One example is co-codamol, which contains codeine combined with paracetamol.
Codeine is also combined with the anti-inflammatory medicine ibuprofène in some over-the-counter products.
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Side effects of codeine
Retour au sommaireCommon side effects of codeine include:
Se sentir mal.
Être malade (vomissements).
Constipation.
Sensation de vertige.
Feeling sleepy.
Stomach (tummy) pain.
Bouche sèche.
Sueurs.
Vous trouverez une liste complète dans la notice d'information du fabricant fournie avec votre médicament.
The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any side effects continue or become troublesome.
How to manage codeine side effects
Retour au sommaireCommon codeine side effects | Que puis-je faire si je ressens cela ? |
Se sentir malade ou être malade | Stick to simple meals - avoid rich or spicy foods. Also, try taking your doses of codeine after food, as this may help protect your stomach |
Constipation | Eat a well-balanced diet and drink plenty of water each day. If this continues to be a problem, speak with your doctor |
Se sentir étourdi ou somnolent | Si cela se produit, ne conduisez pas et n'utilisez pas d'outils ou de machines. Ne buvez pas d'alcool |
Dry mouth, sweating, tummy pain (may be caused by spasm of the bile ducts) | Parlez avec votre médecin si cela pose problème |
Important: people taking opioid medicines, and their family and friends, should be aware of the risk of accidental overdose and know when to seek medical help. The risk is higher if you also take other medicines that make you feel drowsy. Signs you have taken too much medicine include:
Feeling very sleepy or dizzy.
Feeling sick (nausea) or being sick (vomiting).
Difficultés respiratoires.
Loss of consciousness.
If you have taken more codeine than you should or someone else accidentally swallows your medication, call for an ambulance and tell them the name of your medicine.
If you experience other symptoms which you think may be due to codeine, speak with your doctor or pharmacist for further advice.
Who should not take codeine?
Retour au sommaireSome medicines are not suitable for people with certain conditions. Before starting codeine it is important that your doctor knows:
Si vous êtes enceinte ou si vous allaitez.
If you have a problem with the way your liver works, or a problem with the way your kidneys work.
If you have prostate problems or any difficulties passing urine.
If you have any breathing problems, such as asthme ou maladie pulmonaire obstructive chronique (MPOC).
If you have been told you have pression artérielle basse or an abnormal heart rhythm.
If you have any problems with your thyroid or adrenal glands.
Si vous avez épilepsie.
If you have gallstones or a problem with your bile duct.
If you have been constipated for more than a week or have an inflammatory bowel problem.
Si vous avez une affection provoquant une faiblesse musculaire, appelée myasthénie grave.
If you have recently had a severe head injury.
If you have ever been dependent on drugs or alcohol.
Si vous avez déjà eu une réaction allergique à un médicament.
Si vous prenez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et les médecines complémentaires.
How to take codeine
Retour au sommaireRead the leaflet inside the pack before you start. It explains how codeine works and lists possible side effects.
Take codeine exactly as prescribed by your doctor or pharmacist.
The usual dose for pain is 30-60 mg every 4 hours if needed.
Do not take it more often than every 4 hours and do not exceed 240 mg in one day.
Codeine tablets come in different strengths, always check the label to see how many tablets to take.
Swallow the tablets with water. You can take them with or without food, but taking them after food may help prevent feeling sick.
If you forget a dose, take it when you remember, then continue as normal. Ne prenez pas deux doses en même temps to make up for a missed dose.
Tirer le meilleur parti de votre traitement
Retour au sommaireDo not drink alcohol while taking codeine. Alcohol can increase side effects such as dizziness and sleepiness.
Codeine can affect your reactions and driving ability. Do not drive until you know how codeine affects you, especially when you first start taking it. The effects of codeine may last into the next day, even if you feel alert.
If you are driving while taking codeine, carry proof that it has been prescribed for you (such as the patient leaflet or a prescription slip).
Codeine is prescribed for the shortest time needed to reduce the risk of dependence and building a tolerance.
Stopping codeine suddenly after taking it for a while can cause withdrawal symptoms, such as feeling restless or irritable.
If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking codeine.
If you buy any medicines, check with a pharmacist that they are safe to take with codeine.
How to store codeine
Retour au sommaireGardez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.
Informations importantes sur tous les médicaments
Retour au sommaireInformations importantes sur tous les médicaments
Ne prenez jamais plus que la dose prescrite. Si vous soupçonnez que vous ou quelqu'un d'autre avez pris une surdose de ce médicament, rendez-vous au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.
Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.
MHRA - Signaler des réactions indésirables
Signalez les effets secondaires suspectés des médicaments, vaccins, cigarettes électroniques, incidents liés aux dispositifs médicaux, produits défectueux ou falsifiés (contrefaits) à l'Agence de Régulation des Médicaments et Produits de Santé pour garantir une utilisation sûre et efficace.
Questions fréquemment posées
Retour au sommaireHow long does it take for codeine to work?
Codeine usually starts to work within 30 to 60 minutes after taking it, with pain relief typically lasting for around 4 hours. How quickly it works however can vary from person to person.
Is it safe to take codeine during pregnancy?
Codeine can be taken during pregnancy but only for short-term use. It is not recommended during the third trimester as there is a risk that your baby will get used to having codeine and could have withdrawal symptoms.
Can you drink alcohol with codeine?
No, you should not drink alcohol while taking codeine. Alcohol increases the risk of side effects such as drowsiness, dizziness, slowed breathing, and impaired judgement.
Can you take codeine with paracetamol?
Yes, you can take codeine and paracetamol together. They are commonly combined in a medicine called co-codamol. Taking them together can provide better pain relief than either medicine alone.
Is codeine addictive?
Yes, codeine can be addictive if taken regularly or for long periods. Your body can become dependent on it, and stopping suddenly may cause withdrawal symptoms such as restlessness or irritability. For this reason, codeine is usually prescribed for short-term use only.

Vous n'êtes pas sûr de mélanger des médicaments ?
Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.
Lectures complémentaires et références
- Manufacturer's PIL, Codeine Phosphate Tablets 15 mg, 30 mg, 60 mg; Aurobindo Pharma - Milpharm Ltd, The electronic Medicines Compendium. Dated March 2022.
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Historique de l'article
Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.
Next review due: 17 Dec 2026
18 déc. 2023 | Dernière version

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