Médicaments contre la toux
Revu par Dr Colin Tidy, MRCGPDernière mise à jour par Dr Doug McKechnie, MRCGPLast updated 24 juin 2024
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Dans cette série :TouxRhume communToux viraleToux et rhumes chez les enfantsToux chronique persistante chez les adultesToux avec du sang
Cough medicines are commonly bought to treat various types of coughs that occur when you have an upper respiratory tract infection (URTI). Cough medicines that you can buy are often divided into those for a dry or tickly cough, and those for a chesty cough. It is thought that cough medicines do not really work.
However, some people feel that they work for them and they are thought to be reasonably safe to use, though it is important to check with a pharmacist if you are taking other medications. Children who are aged 12 years and younger should only be given cough syrups which state they are suitable for the child's age.

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Video picks for Médicaments respiratoires
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What are cough medicines?
Cough medicines or cough syrups aim either to suppress a dry cough, or to help you to cough up the phlegm (mucus) of a chesty cough when you have a URTI. There is no good evidence that they do help. This is partly because many coughs get better quickly on their own anyway, so it is hard to tell if the cough medicine has helped or if the cold has simply got better.
Lots of cough medicines are available to buy from pharmacies or supermarkets. They usually contain one or more active ingredient (see the section below).
A glycerin, honey and lemon cough medicine is also available to buy. This preparation does not have an active ingredient as such. It is thought to have a soothing action.
Cough medicines can also contain other medicines such as paracetamol or ibuprofen. Some contain alcohol.
How do cough medicines work?
Retour au sommaireIf cough medicines do work, they are thought to work in different ways, depending on what the active ingredient is:
Antitussives are said to work by reducing the cough reflex. For example, dextromethorphan.
Expectorants try to help loosen secretions, so you cough up the mucus. For example, guaifenesin or ipecacuanha.
Antihistaminiques reduce histamine release. This reduces congestion and decreases the amount of phlegm made by the lungs. Examples are brompheniramine, chlorphenamine, diphenhydramine, doxylamine, promethazine or triprolidine.
Décongestionnants cause the blood vessels in the lungs and nose to narrow (constrict), which reduces congestion in the nose. Examples are phenylephrine, pseudoephedrine, ephedrine, oxymetazoline or xylometazoline.
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Do cough medicines really work?
Retour au sommaireThere is no good evidence from research studies that cough medicines work. It is thought that they have little benefit on the cough (or cold) symptoms. However, some people feel that they work for them, and most cough medicines are considered to be safe for the vast majority of adults and for children over 6 years old.
Which cough medicine should I buy?
Retour au sommaireIf you have a dry cough, a preparation containing an antitussive such as dextromethorphan is the most suitable to try. If you have a chesty cough, a preparation containing an expectorant such as guaifenesin or ipecacuanha is the most suitable to try.
Your pharmacist can advise you which one may be suitable for you. If you are buying these cough medicines from the supermarket, the box should clearly state which type of cough it aims to help and what the ingredients are.
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Cough medicine for children
Retour au sommaireChildren under 6 years old
Children under 6 years of age should only be given simple cough syrups such as glycerin, honey, and lemon. Cough syrup boxes will show what age of child it is appropriate for. Do not give children who are younger than 6 years old cough syrups with any of the active ingredients listed above (antitussives, expectorants, antihistamines, or decongestants). This is because the risk of a young child having a side-effect to one these preparations is greater than any possible benefit of the cough medicine.
Children aged 6 to 12
Children older than 6 years old can usually take cough medicines safely. In the UK, they are only sold for the use of children aged 6 to 12 with the advice of a pharmacist. Consider other soothing measures first as any cough medicines can have side-effects.
Prendre d'autres médicaments
Retour au sommaireAlways check with your pharmacist before buying any cough medicines from the chemist or supermarket to see if they are safe to take with any other medicines you may be taking.
Some cough medicines contain other medicines as well. For example, some may contain paracetamol or ibuprofen, and some contain alcohol. This is important if you are already taking paracétamol ou ibuprofène to help the symptoms of your infection (for example, a high temperature). This is because you may take too much paracetamol or ibuprofen (an overdose) but not be aware of it. Taking too much paracetamol can seriously damage your liver.
Monoamine-oxidase inhibitors
If you are taking a particular type of antidepressant - a monoamine-oxidase inhibitors (MAOI) - this can react with certain ingredients in cough medicines. Taking these together can cause a very large sudden increase in blood pressure, or make you very excitable or depressed.
In particular, people taking MAOIs should avoid dextromethorphan, ephedrine, pseudoephedrine or phenylpropanolamine while they are taking an MAOI antidepressant and for two weeks after it is stopped:
Dextromethorphan when taken with an MAOI antidepressant may make you very excitable or depressed.
Ephedrine, pseudoephedrine and phenylpropanolamine, when taken at the same time as an MAOI antidepressant, may cause very large increases in blood pressure.
Cough medicine side-effects
Retour au sommaireMost people who take cough medicines do not have side-effects. Some cough medicines (for example, diphenhydramine) can cause drowsiness. If you are drowsy after taking a cough medicine, you should not drive and you should not operate machinery. The leaflet that comes with your cough medicine will state if the medicine can cause drowsiness.
Remarque: the above is not the full list of side-effects for these cough medicines. Please see the leaflet that comes with your particular brand for a full list of possible side-effects and cautions.
Quelle est la durée habituelle du traitement ?
Retour au sommaireAs with all medicines, cough medicines should only be taken for the shortest period of time necessary, most people only use a cough medicine for a few days. In general, most coughs do not last more than 2-3 weeks. If your cough does last longer than three weeks then you should go to see your doctor.
Who cannot take cough medicines?
Retour au sommaireMost people can take a cough medicine. The exception is children under the age of 6 years. These children should only be given cough syrups with no active ingredients (see above).
Cough medicines for children aged 6 to 12 are only sold with the advice of a pharmacist. If you are taking any other medicines or you are not sure if you should take a cough medicine, check with your pharmacist.
Patient picks for Médicaments respiratoires

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Bronchodilatateurs oraux
Les bronchodilatateurs oraux sont des médicaments parfois utilisés pour traiter les problèmes respiratoires chez les personnes souffrant d'asthme et d'autres problèmes pulmonaires tels que la maladie pulmonaire obstructive chronique (MPOC). Ils ne sont pas utilisés très souvent, car les bronchodilatateurs inhalés fonctionnent généralement mieux. Il existe deux types de bronchodilatateurs oraux disponibles sur ordonnance au Royaume-Uni. Ce sont les agonistes bêta2 (salbutamol, bambutérol et terbutaline) et les méthylxanthines (théophylline et aminophylline). Les bronchodilatateurs oraux aident à soulager les symptômes tels que la toux, la respiration sifflante et l'essoufflement, en ouvrant les voies respiratoires dans les poumons pour que l'air puisse y circuler plus librement.
par Dr Doug McKechnie, MRCGP

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Sprays nasaux stéroïdiens
Les sprays nasaux stéroïdiens sont des médicaments couramment utilisés pour traiter les symptômes de congestion ou d'obstruction nasale. Ils sont le plus souvent utilisés pour les allergies nasales, telles que le rhume des foins. Ils sont également utilisés pour d'autres causes d'inflammation persistante du nez (rhinite). Les sprays stéroïdiens réduisent le gonflement et le mucus dans le nez, et fonctionnent généralement bien. Les personnes souffrant de rhume des foins n'ont besoin de les utiliser que quelques mois par an. D'autres peuvent avoir besoin de les utiliser à long terme. Vous pouvez acheter certains sprays nasaux stéroïdiens dans votre supermarché ou pharmacie locale, sans ordonnance.
par Dr Rachel Hudson, MRCGP

Vous n'êtes pas sûr de mélanger des médicaments ?
Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.
Lectures complémentaires et références
- Médicaments contre la toux et le rhume en vente libre pour enfants; Agence de Régulation des Médicaments et Produits de Santé (MHRA), 2014
- Formulaire National Britannique (BNF); Services de Preuves NICE (accès réservé au Royaume-Uni)
- Smith SM, Schroeder K, Fahey T; Over-the-counter (OTC) medications for acute cough in children and adults in community settings. Cochrane Database Syst Rev. 2014 Nov 24;11:CD001831. doi: 10.1002/14651858.CD001831.pub5.
- Morice A, Kardos P; Comprehensive evidence-based review on European antitussives. BMJ Open Respir Res. 2016 Aug 5;3(1):e000137. doi: 10.1136/bmjresp-2016-000137. eCollection 2016.
- Toux; NICE CKS, août 2023 (accès réservé au Royaume-Uni)
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Historique de l'article
Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.
Prochaine révision prévue : 24 juin 2027
24 juin 2024 | Dernière version
15 Mar 2012 | Publié à l'origine
Écrit par :
Jenny Whitehall

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