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Acide folique

folate - FolicA, FoliSol, Lexpec

As well as taking folic acid, try to eat a healthy diet containing lightly cooked green leafy vegetables.

Folic acid rarely causes side-effects.

At a glance

  • Folic acid is a vitamin (B9) important for growth and general health, also called folate.

  • It is used to treat folic acid deficiency and a type of anaemia.

  • Pregnant women should take folic acid to reduce the risk of birth defects like spina bifida.

  • Begin taking folic acid before pregnancy and continue for at least the first 12 weeks.

  • Folic acid is also used with methotrexate in some conditions to reduce side-effects.

  • You can buy 400 microgram tablets, but your doctor will prescribe 5 mg tablets.

  • Folic acid supplements are unlikely to cause side-effects.

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About folic acid

Type de médicament

Vitamin B9

Utilisé pour

Folic acid deficiency in adults and children; folic acid supplementation before/during pregnancy

Aussi appelé

Folate; FolicA®; FoliSol®; Lexpec®
Combination brand: Ferrograd Folic® (folic acid with ferrous fumarate)

Disponible sous forme de

Tablets and oral liquid

Folic acid in anaemia

Vitamins are substances required by our bodies in small amounts for growth and general health. Our bodies do not store very much folic acid so we need to have a regular fresh supply. We can usually get the amounts we need from the food that we eat. Many foods contain folic acid, including spinach, sprouts, broccoli, green beans, peas, chickpeas, brown rice, kidney, liver and potatoes. Some people, for various reasons, may not receive enough from their diet alone. Folic acid is important for the production of red blood cells. A lack of it can lead to anaemia, which can cause tiredness and sometimes other symptoms. Folic acid deficiency is treated easily by taking a course of folic acid tablets for a few months.

Folic acid in pregnancy

Pregnant women in particular need a good supply of folic acid because it is used by the developing baby. It has been shown that taking folic acid supplements decreases the chance of spina bifida and other neural tube defects in the baby. The very early stages of pregnancy are crucial in the need for folic acid and this is why folic acid supplements are recommended for women planning a pregnancy.

Extra folic acid is advised for at least the first 12 weeks of la grossesse for all women - even if you are healthy and have a good diet. For most women, a supplement of 400 micrograms of folic acid a day from before conception until the twelfth week of pregnancy is recommended. It is best to start taking the extra folic acid before becoming pregnant. If the pregnancy is unplanned then start taking folic acid as soon as you know you are pregnant. You can buy tablets of folic acid at most health food shops or pharmacies.

If you have had a previous pregnancy affected by a neural tube defect or if there is a family history of such, a supplement of 5 mg (milligrams) of folic acid each day until the twelfth week is recommended. A supplement of 5 mg daily in pregnancy is also recommended with some medical conditions such as coeliac disease, diabetes, and sickle cell anaemia, and if you are taking medicines to treat epilepsy. This strength of folic acid tablet is not available to buy. Your doctor will prescribe the tablets for you.

Folic acid in other conditions

Folic acid is also used alongside méthotrexate treatment in people with severe maladie de Crohn, psoriasis, and l'arthrite. When it is used in these medical conditions, folic acid is taken on a different day of the week to methotrexate. It is taken to reduce the side-effects which can be caused by methotrexate.

  • If you have bought folic acid tablets because you are planning to have a baby, read the manufacturer's printed information on the pack (or from inside it) before you start taking the tablets. Make sure you are clear about what dose to take - the recommended dose is 400 micrograms once daily. The 5 mg tablet has more than ten times as much folic acid as this. If you have any questions, ask a pharmacist to advise you.

  • If you have been prescribed 5 mg folic acid tablets by a doctor, take them exactly as you are told to. Depending upon the reason for which you are taking folic acid, you may be asked to take one tablet every day, or one tablet only on certain days of the week. Try to take your doses at the same time of day each day that you take them, as this will help you to remember to take the tablets regularly. There will be more information about folic acid on the manufacturer's printed information leaflet from inside your pack.

  • It is not important whether you take folic acid before or after meals.

  • If you forget to take a tablet, take it as soon as you remember. If you do not remember until the following day, skip the forgotten dose. Do not take two doses at the same time to make up for a missed dose.

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  • In addition to taking folic acid, try also to eat a healthy diet including foods rich in folic acid, such as spinach, sprouts, broccoli, green beans and potatoes. Lightly cook the vegetables, as the cooking process reduces the amount of folic acid they contain. Some bread and breakfast cereals are fortified with folic acid also.

Folic acid supplements are unlikely to cause any side-effects. The 5 mg tablets may, on rare occasions, cause mild upset stomach (loss of appetite, nausea, and a bloated feeling). If you experience any symptoms which you think may be due to the tablets, speak with your doctor or pharmacist for advice.

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Informations importantes sur tous les médicaments

Ne prenez jamais plus que la dose prescrite. Si vous soupçonnez que vous ou quelqu'un d'autre avez pris une surdose de ce médicament, rendez-vous au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.

Si vous subissez une opération ou un traitement dentaire, informez la personne qui effectue le traitement des médicaments que vous prenez.

Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.

Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.

Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.

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Questions fréquemment posées

What foods can help me get enough folic acid naturally?

Many foods contain folic acid, including spinach, sprouts, broccoli, green beans, peas, chickpeas, brown rice, kidney, liver and potatoes. Some bread and breakfast cereals are also fortified with folic acid. It's best to lightly cook vegetables such as spinach and broccoli, as extensive cooking can reduce their folic acid content.

If I am pregnant, when should I start taking folic acid?

It is best to start taking extra folic acid before becoming pregnant. If your pregnancy is unplanned, you should start taking folic acid as soon as you find out you are pregnant. Supplementation is recommended from before conception until the twelfth week of pregnancy.

What is the recommended dose of folic acid for most pregnant women?

For most women, a daily supplement of 400 micrograms of folic acid is recommended from before conception until the twelfth week of pregnancy. You can buy this strength of folic acid at most health food shops or pharmacies.

Are there any specific medical conditions or circumstances where a higher dose of folic acid is recommended during pregnancy?

Yes, a higher dose of 5 mg of folic acid each day until the twelfth week of pregnancy is recommended if you have had a previous pregnancy affected by a neural tube defect, or if there is a family history of such. This higher dose is also advised for some medical conditions like coeliac disease, diabetes, and sickle cell anaemia, or if you are taking medicines for epilepsy. This 5 mg strength requires a prescription from your doctor.

If I miss a dose of my folic acid tablets, what should I do?

If you forget to take a tablet, take it as soon as you remember. However, if you don't remember until the following day, you should skip the forgotten dose. Do not take two doses at the same time to make up for a missed dose.

Can folic acid be taken at any time of day, with or without food?

Yes, it is not important whether you take folic acid before or after meals. It's suggested to try and take your doses at the same time each day you take them to help you remember to take them regularly.

Are there any common side effects from taking folic acid supplements?

Folic acid supplements are generally unlikely to cause any side-effects. On rare occasions, the higher strength 5 mg tablets may cause mild upset stomach, which can include loss of appetite, nausea, and a bloated feeling.

Lectures complémentaires et références

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About the authorView full bio

Author image

Michael Stewart, MRPharmS

Medicine Leaflet Review Manager – Contractor, Pharmacist

BPharm (Hons), MRPharmS

Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.

About the reviewer

Author image

Sid Dajani

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

Historique de l'article

Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.

  • Prochaine révision prévue : 15 oct. 2027
  • 17 avr. 2023 | Dernière version

    Dernière mise à jour par

    Michael Stewart, MRPharmS

    Revu par

    Sid Dajani
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