Diamorphine pour le soulagement de la douleur
Revu par Dr Colin Tidy, MRCGPDernière mise à jour par Michael Stewart, MRPharmSLast updated 19 janv. 2023
Respecte les directives éditoriales
- TéléchargerTélécharger
- Partager
- Language
- Discussion
- Version audio
Diamorphine is prescribed to treat severe pain.
It will usually be given to you by a doctor or nurse as an injection. A nasal spray may sometimes be used for children in hospital.
The most common side effects of diamorphine are constipation, drowsiness, and feeling sick (nausea).
Dans cet article:
Video picks for Analgésiques et médicaments contre la douleur
Continuez à lire ci-dessous
About diamorphine
Type de médicament | Strong opioid painkiller |
Utilisé pour | Severe pain |
Aussi appelé | Diacetylmorphine (in US) |
Disponible sous forme de | Injection, tablets and nasal spray |
What is diamorphine used for?
Retour au sommaireDiamorphine is a analgésique opioïde puissant used in particular to treat pain after a surgical operation and pain caused by le cancer.
It may also be used following a crise cardiaque, or for breathlessness caused by fluid in the lungs. It works on your nervous system and brain to reduce the amount of pain you feel.
Continuez à lire ci-dessous
What is diamorphine available as?
Retour au sommaireDiamorphine is available as:
An injection.
Spray nasal.
Tablettes.
Diamorphine is usually given by injection. Tablets are rarely prescribed because other strong opioids, such as morphine, are absorbed better when taken by mouth.
For children with severe pain, diamorphine may be given as a nasal spray in hospital emergencies. This is quicker and less distressing than an injection.
Side effects of diamorphine
Retour au sommaireCommon side effects of diamorphine are:
Feeling drowsy or sleepy.
Sensation de vertige.
Se sentir mal.
Être malade (vomissements).
Constipation.
Bouche sèche.
You will find a full list in the manufacturer's information leaflet supplied with your medicine.
Les effets indésirables s'améliorent souvent à mesure que votre corps s'adapte au nouveau médicament, mais consultez votre médecin ou votre pharmacien si des effets secondaires persistent ou deviennent gênants.
Continuez à lire ci-dessous
How to manage diamorphine side effects
Retour au sommaireCommon diamorphine side effects | Que puis-je faire si je ressens cela ? |
Feeling dizzy, sleepy or drowsy, blurred vision | Ne conduisez pas et n'utilisez pas d'outils ou de machines. Ne buvez pas d'alcool |
Se sentir malade ou être malade | Stick to simple meals - avoid rich or spicy foods. Your doctor may prescribe a medicine to ease the sickness |
Constipation | Eat a well-balanced diet and drink plenty of water each day. If this continues to be a problem, speak with your doctor |
Bouche sèche | Take frequent sips of water. Try chewing sugar-free gum or sucking sugar-free sweets |
Other side effects of diamorphine include: sweating, feeling confused, difficulties passing urine, flushing, the sensation of having a 'thumping heart' (palpitations), mood changes, reduced appetite, rash, and itching | Si l'un de ces éléments devient problématique, parlez-en à votre médecin |
Si vous ressentez d'autres symptômes que vous pensez être dus à ce médicament, parlez-en à votre médecin ou à votre pharmacien.
Important : if you are caring for someone who has recently been given a dose of diamorphine and you notice the following side effects, alert a doctor or nurse as soon as possible:
Very small, 'pinpoint' pupils (the black circle of the eye).
Shallow breathing or difficulty breathing.
Losing consciousness (falling asleep).
Having a fit (seizures or convulsions).
Who should not have diamorphine?
Retour au sommaireSome medicines are not suitable for people with certain conditions. Before taking diamorphine it is important that your doctor knows:
Si vous êtes enceinte, essayez d'avoir un bébé, ou allaitez.
If you have heart, liver, or kidney problems.
Si vous avez des problèmes de prostate ou des difficultés à uriner.
If you have any breathing problems, such as asthma or maladie pulmonaire obstructive chronique (MPOC).
If you have been told you have low blood pressure (hypotension).
Si vous avez des problèmes avec votre thyroïde ou vos glandes surrénales.
If you have épilepsie.
Si vous avez un problème avec votre canal biliaire.
If you have severe diarrhoea, or have been constipated for more than a week, or have an inflammatory bowel problem.
If you have a condition causing muscle weakness, called myasthénie grave.
Si vous avez récemment subi une blessure grave à la tête.
If you have ever had a mental health problem called psychose.
Si vous avez déjà été dépendant aux drogues ou à l'alcool.
Si vous avez déjà eu une réaction allergique à un médicament.
Si vous prenez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et les médecines complémentaires.
How diamorphine is given
Retour au sommaireDiamorphine is usually given as an injection into a muscle or directly into a vein. A doctor or nurse will give the injection, and it may be repeated every four hours to control pain.
Diamorphine can also be given as an injection just under the skin, often using a syringe driver.
A syringe driver is a small device that delivers controlled doses through a needle that stays in place. This allows pain relief to be given when needed, without repeated injections. The device limits how much diamorphine can be given over 24 hours.
In hospital, children with severe pain may be given diamorphine as a nasal spray. This provides fast pain relief and is often used in emergencies. The dose depends on the child’s weight.
Tirer le meilleur parti de votre traitement
Retour au sommaireRead the patient information leaflet that comes with the medicine. It explains how diamorphine works and lists possible side effects.
Ask your doctor about alcohol. You may be advised not to drink alcohol while taking diamorphine, as it can increase side effects such as dizziness and drowsiness.
Driving may be affected. Diamorphine can slow your reactions and make driving unsafe. It is illegal to drive if your ability is impaired. If you do drive, carry proof that the medicine has been prescribed for you.
If you are travelling abroad and need to take diamorphine with you, carry a letter from your doctor. Diamorphine is a controlled drug and is subject to legal restrictions in many countries.
Check other medicines first. Some over-the-counter medicines can increase side effects when taken with diamorphine. Ask a pharmacist before taking any new medicine.
Tell healthcare professionals that you are taking diamorphine before having any other treatment.
Diamorphine is used for short periods only. Long-term use can lead to dependence and withdrawal symptoms such as restlessness or irritability. Speak to your doctor or pharmacist if you are concerned.
How to store diamorphine
Retour au sommaireGardez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.
Informations importantes sur tous les médicaments
Retour au sommaireInformations importantes sur tous les médicaments
Ne prenez jamais plus que la dose prescrite. Si vous soupçonnez que vous ou quelqu'un d'autre avez pris une surdose de ce médicament, rendez-vous au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.
Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Yellow Card website.
Questions fréquemment posées
Retour au sommaireHow long does it take for diamorphine to work?
Diamorphine usually starts to work in 15-20 minutes when injected into a muscle, such as your thigh or bottom, and lasts for 2-4 hours.
Is it safe to have diamorphine during pregnancy?
Diamorphine is usually only used early in pregnancy. Using it for a long time can cause the baby to become dependent and have withdrawal symptoms after birth. If taken close to delivery, it can also affect the baby’s breathing
What's the difference between diamorphine and morphine?
Diamorphine is a stronger and faster-acting form of morphine. Once in the body, diamorphine is converted into morphine, but it reaches the brain more quickly, providing faster pain relief.
Is diamorphine addictive?
Yes, diamorphine can be addictive, especially with regular or long-term use. It can cause dependence, meaning you may experience withdrawal symptoms if it is stopped suddenly.

Vous n'êtes pas sûr de mélanger des médicaments ?
Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.
Lectures complémentaires et références
- Manufacturer's PIL, Diamorphine Hydrochloride BP for Injection 5 mg, 10 mg, 30 mg, 100 mg, 250 mg and 500 mg; Wockhardt UK Ltd, The electronic Medicines Compendium. Dated April 2020.
Continuez à lire ci-dessous
Historique de l'article
Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.
Next review due: 18 Jul 2027
19 janv. 2023 | Dernière version

Demandez, partagez, connectez-vous.
Parcourez les discussions, posez des questions et partagez vos expériences sur des centaines de sujets de santé.
Inscrivez-vous à la newsletter Patient
Votre dose hebdomadaire de conseils de santé clairs et fiables - rédigés pour vous aider à vous sentir informé, confiant et maître de la situation.
By subscribing you accept our Politique de confidentialité. Vous pouvez vous désabonner à tout moment. Nous ne vendons jamais vos données.